Gene Therapy Account Manager

Job Description

General Summary:

At Vertex, we’re relentless in our pursuit of scientific innovation to create transformative medicines for people with serious diseases.  We are currently seeking a Gene Therapy Account Manager (GTAM) to support our Sickle Cell Disease (SCD) and Transfusion-dependent β-thalassemia (TDT) Heme Business Unit. 

This role is responsible for the Southeast territory which includes FL, GA and AL

As part of a national team, the Gene Therapy Account Manager, Associate Director (GTAM) will approach each day with a passion for improving the lives of people living with Sickle Cell Disease and Transfusion-dependent β-thalassemia. This role is focused on Key Account Management (65%) and Access/Reimbursement (35%) as a customer centric, results-driven individual contributor that supports operational readiness and access for the safe and effective use of Casgevy to medical providers per assigned coverage plans.

The GTAM serves as a single point of contact for covering Activated Treatment Centers (ATC) and manages those accounts.  This role serves as a team player and problem solver. The GTAM proactively identifies opportunities for improvement, takes ownership of driving toward solutions, progress and positive change. This role must effectively collaborate with internal and external stakeholders and possess mental resilience.  

Key Responsibilities:

• Serve as primary point of contact (POC) between authorized treatment centers (ATC) and internal cross-functional partners to support patient access, reimbursement and operational readiness. Act as the primary interface for customer needs throughout the patient journey, ensuring timely triaging (as needed) to the appropriate subject matter experts and internal stakeholders to remove barriers and facilitate seamless care delivery.
• Support ATCs and affiliated referral networks; including ongoing training and education throughout and after the onboarding and activation process, ensuring order readiness across patient services, reimbursement pathways, and site operations both during and after activation.
• Coordinate Vertex tasks related to ATC goals/demands with cross-functional partners to ensure seamless coordination within the site.
• Compliantly educate on the Casgevy profile and patient journey, in accordance with the product label and company training and policies.
• Build and maintain strong relationships with key stakeholders (e.g., HCPs, C-Suite level personnel, administrators, pharmacists, and care coordinators involved in Gene Therapy delivery key decision makers) at sites of care and referring sites, with the goal of building awareness for Casgevy.
• Develop and execute comprehensive account and HCP engagement strategy for ATCs; track and report progress towards KPIs and patient journey milestones.
• Collaborate with cross-functional stakeholders to ensure HCPs and other account-based decision-makers have timely access to critical solutions and necessary support to facilitate a wide breath of conversations from manufacturing to patient support.
• Own account planning and lead field team coordination to internally drive future account success; facilitates and provides appropriate and timely feedback to Vertex cross functional partners, management and key stakeholders regarding account level business trends, changes in the therapeutic landscape, business issues and opportunities.
• Maintains strong and deep clinical expertise in Hematology, including Sickle Cell Disease (SCD), Transfusion-dependent B-thalassemia (TDT) and Hematopoietic Stem Cell Transplantation (HSCT).
• Acts as a bridge between the company and Key Thought Leaders with consistent conference attendance to foster strong relationships, share insights, and inform strategic initiatives.
• Communicate access and reimbursement principles, payer coverage (including CMMI), hospital coding, SP/SD differences, and pharmacy operations for a complex new technology and escalates complex access and reimbursement topics to Access and Reimbursement (ARL) team.
• Conversant in billing & coding guide and understands the claims submission and appeals process and appropriately initiates the escalation process.
• Ability to think broadly, strategically, analytically, and thrive in a fast-changing environment. Can operate independently as a self-starter and successfully in a fast paced, ambiguous environment
• Deep understanding of health systems and hospitals, and the ability to develop and drive system level matrix planning and execution
• Ability to operate and appropriately access and handle business information in compliance with all applicable laws, regulations and / or Vertex policies

Required Education/Experience:

• Bachelor’s Degree is required
• Minimum of 8 years of experience in key account management, sales management, account management
• Experience in specialized Biotech, Device, Laboratory, or specialty field sales environments, such as Cell and Gene therapy, Hematology, Transplant, Oncology/Immunology, rare disease experience or clinical experience within the Sickle Cell Disease (SCD), Bone Marrow Transplant (BMT) or Cell & Gene settings
• Basic knowledge and understanding of compliance with HIPPA
• Hospital finance, claims processing, and/or billing/coding experience preferred (e.g., inpatient and outpatient along the journey) and CMMI basics
• Primary understanding of the prior auth process, denial management, product acquisition via the specialty pharmacy, buy-and-bill, IV infusion coding and reimbursement within multiple sites of care
• Understands both the buy-and-bill process and specialty pharmacy networks, managed care, benefit design, government payers and their impact on product access with excellent working knowledge of evolving market access and reimbursement landscape
• Valid driver’s license and in good standing
• Ability to travel up to all assigned coverage location

At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.

Pay Range:

$160,000 - $240,000

Disclosure Statement:

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [email protected]