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Isomorphic Labs

AI-powered drug discovery and development

Technical Program Manager

Full-TimeUpdated on 10/23/2026
No salary listed
Mid
Bachelor's
Cambridge, MA, USA
HybridHybrid; required in-office attendance 3 days per week.
Project & Program ManagementProgram Management

About the job

Requirements
  • A BSc in Biology, Chemistry, or a related discipline is required.
  • Proven industry experience contributing to, managing, or leading early-stage or discovery small-molecule, glue, or peptide drug-design programs.
  • Understanding of small-molecule, glue, or peptide drug discovery and development processes in the context of project and program planning and governance.
  • Experience managing budgets, including planning, forecasting, monitoring, troubleshooting, and identifying efficiencies.
  • Experience with operational program management processes.
  • Experience with program risk management.
  • Experience supporting teams in fast-paced and constantly changing environments.
  • Ability to interact adaptively and communicate confidently with diverse key stakeholders.
Responsibilities
  • Support DDMR with program planning, dynamic timeline monitoring, action tracking, risk reporting, effective meetings, and stakeholder management.
  • Manage and monitor program budgets, including forecasting and actual spend, to support program teams, DDMR, and the Technical Program Management team, and report to senior stakeholders.
  • Help program teams liaise effectively with contract research organizations and other external providers or partners, including assisting with contract reviews and processing.
  • Help build and embed processes and operating systems, ensuring integration and alignment across Isomorphic Labs.
Desired Qualifications
  • An advanced degree in Biology, Chemistry, or a related discipline.
  • A program management qualification.
  • Experience working in a machine-learning drug-discovery environment.
  • Experience working with Jira, Confluence, or other program management software.

About the company

Isomorphic Labs uses artificial intelligence to speed up drug discovery and development. It applies machine learning and computational methods—building predictive and generative models—to accelerate how drugs are designed and how medical research is conducted. The company differentiates itself by combining the AI breakthroughs from Google DeepMind with Alphabet backing, enabling fast experimentation and scaling across biology while maintaining startup-style agility. Its goal is to bring safer, more effective therapies to market more quickly by advancing AI-driven medicine using deep learning, reinforcement learning, and other advanced techniques.

Company Size

201-500

Company Stage

Series B

Total Funding

$2.7B

Headquarters

London, United Kingdom

Founded

2021

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Simplify's Take

What believers are saying

  • May 12, 2026 Series B raised $2.1 billion, funding clinical execution.
  • The company expanded with Johnson & Johnson on January 20, 2026.
  • Novo-validated partnerships and capital support hiring across AI, chemistry, and clinical teams.

What critics are saying

  • No Isomorphic-designed drug reached human dosing by September 13, 2026.
  • Reuters reported first trials slipped from 2025 to end-2026.
  • Proprietary IsoDDE keeps methods opaque; one failed clinical readout would crush credibility.

What makes Isomorphic Labs unique

  • Google DeepMind spinout, launched 2021, built on AlphaFold and IsoDDE.
  • IsoDDE, released February 10, 2026, claims better generalization than AlphaFold 3.
  • Johnson & Johnson joined Lilly and Novartis, validating multi-modality discovery across targets.

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Benefits

  • Hybrid Work Options

Growth & Insights and Company News

6 month growth

0%

1 year growth

0%

2 year growth

1%
Dubai Eye 103.8
Oct 21st, 2026
Abu Dhabi to advance AI-driven drug discovery under new agreement.

Abu Dhabi to advance AI-driven drug discovery under new agreement. Wednesday, 21 October 2026 at 13:54 By ARN News Staff Abu Dhabi's health authority has signed an agreement with Isomorphic Labs to collaborate on AI-enabled drug discovery research and explore innovation frameworks for pre-clinical research. The agreement aims to develop a pre-clinical research roadmap for selected AI-enabled discovery projects over a 24-month period, with research conducted within Abu Dhabi's Trusted Research Environment. "Artificial intelligence is changing not only how quickly we discover new medicines, but how precisely we can target disease. Realising that potential requires more than technology. It requires rich clinical and genomic data, a research environment that can translate insight into discovery, and regulation that advances at the pace of science," explained Mansoor Ibrahim Al Mansoori, Chairman of DoH. The agreement was signed at the Abu Dhabi Future Health Summit by Dr. Noura Khamis Al Ghaithi, Undersecretary of Department of Health - Abu Dhabi (DoH), and Max Jaderberg, President of Isomorphic Labs. The collaboration reflects the health authority's efforts in enabling responsible use of predictive and generative AI in health research to accelerate the development of new medicines in the emirate.

Forbes Middle East
Oct 21st, 2026
Mubadala Bio, Eli Lilly to establish pharmaceutical packaging operations in Abu Dhabi.

Mubadala Bio, Eli Lilly to establish pharmaceutical packaging operations in Abu Dhabi. Oct 21, 2026, 4:33 AM Representatives of Mubadala Bio and Eli Lilly announce their pharmaceutical collaboration during the Abu Dhabi Future Health Summit 2026. image by: ADMediaOffice Abu Dhabi-based Mubadala Bio and US pharmaceutical company Eli Lilly have signed an agreement to establish local packaging and logistics operations for the drugmaker's weight-management medicines, Mounjaro and Foundayo, at a 125,000-square-meter site in Abu Dhabi, according to the Abu Dhabi Media Office on Tuesday. Mubadala Bio and Eli Lilly. The companies plan to introduce pharmaceutical packaging and logistics operations at a site in Khalifa Economic Zones Abu Dhabi (KEZAD), supporting Mubadala Bio's contract manufacturing and distribution activities. Implementation will take place in phases, subject to technical, quality, and regulatory approvals. The partnership was among several healthcare agreements announced at the Abu Dhabi Future Health Summit 2026, held from October 20 to 22, covering pharmaceutical supply chains, clinical research, AI-enabled drug discovery, and preventive healthcare. The agreement covers Lilly's GLP-1 medicines, including Mounjaro, which contains tirzepatide, and Foundayo, an oral weight-management medicine containing orforglipron. Hamad Almarzooqi, Mubadala Bio's group deputy CEO, and Nabil Daoud, Lilly's president and general manager for the Intercontinental Hub, announced the partnership at the summit. Neither company disclosed the agreement's financial value, expected production capacity, employment targets, or operational launch date. According to the Abu Dhabi Media Office, the UAE approved Foundayo for chronic weight management in April 2026, becoming the second country to register the treatment. Mounjaro entered the UAE market in August 2022. AstraZeneca partnership. The Department of Health-Abu Dhabi (DoH), Cleveland Clinic Abu Dhabi, and AstraZeneca will assess the feasibility of conducting up to 30 clinical trials in the emirate by 2030. The proposed research will focus on cardiovascular, renal, and metabolic diseases. The collaboration could generate an estimated $50 million (AED 180 million) in life sciences research investment by 2030, according to the Abu Dhabi Media Office. The first six trials are expected to begin at Cleveland Clinic Abu Dhabi before the end of 2026. The announcement did not confirm that all proposed trials had received regulatory approval or that the full investment amount had been committed. AI drug discovery and preventive healthcare. DoH and Isomorphic Labs agreed to a 24-month collaboration to develop a preclinical research roadmap for AI-enabled drug discovery. The initiative will explore the use of Abu Dhabi's clinical and genomic data within the company's Trusted Research Environment. Separately, DoH and WHOOP established a two-year research program using wearable health data to study cardiovascular and metabolic health. WHOOP's initial six-month study will examine whether continuous monitoring and personalized coaching influence weight, blood pressure, cholesterol, blood sugar, and sleep among adults with obesity and hypertension. The collaborations aim to develop locally relevant clinical evidence and strengthen the emirate's preventive healthcare capabilities. M42 healthcare agreements. M42, Oracle, and AstraZeneca announced a nonbinding initiative to explore the use of AI and electronic health records to identify patients with uncontrolled hypertension and potential clinical trial participants. Separately, M42 and Bahrain's Future Generations Reserve Fund signed an agreement to secure a location for a new healthcare facility in Bahrain Bay. The facility is expected to offer multidisciplinary healthcare services, expanding M42's presence in the kingdom. Neither initiative has a disclosed investment value or announced implementation date. Forbes ranking. Mubadala Bio Group CEO Essam Mohamed ranked 18th on Forbes Middle East's Top Healthcare Leaders 2026 - Executives list. The company operates a portfolio of eight manufacturing businesses across Asia, Africa, and Europe, including four in the UAE, serving more than 50 countries, according to Forbes Middle East. In 2026, Mubadala Bio also acquired Al Ittihad Drug Store and Global Medical Supply Chain.

Abu Dhabi Media Office
Oct 21st, 2026
In the presence of Theyab bin Mohamed bin Zayed, Department of Health - Abu Dhabi signs agreements to advance research in life sciences, personalised preventive health, and AI drug discovery.

In the presence of Theyab bin Mohamed bin Zayed, Department of Health - Abu Dhabi signs agreements to advance research in life sciences, personalised preventive health, and AI drug discovery. In the presence of His Highness Sheikh Theyab bin Mohamed bin Zayed Al Nahyan, Deputy Chairman of the Presidential Court for Development and Fallen Heroes' Affairs, the Department of Health - Abu Dhabi (DoH) has signed agreements with Isomorphic Labs, WHOOP, and Cleveland Clinic Abu Dhabi, and AstraZeneca. DoH and Isomorphic Labs announced the signing of an agreement to collaborate on AI-enabled drug discovery research and explore innovation frameworks for pre-clinical research. The agreement was signed at the Abu Dhabi Future Health Summit by Her Excellency Dr Noura Khamis Al Ghaithi, Undersecretary of the Department of Health - Abu Dhabi, and Max Jaderberg, President of Isomorphic Labs. Under the agreement, the collaboration aims to develop a pre-clinical research roadmap for selected AI-enabled discovery projects over a 24-month period, with research conducted within Abu Dhabi's Trusted Research Environment. Isomorphic Labs has built a world-leading drug design engine (IsoDDE) comprised of foundational AI models to provide the predictive fidelity required to navigate novel biological systems with unprecedented accuracy. His Excellency Mansoor Ibrahim Al Mansoori, said: "Artificial intelligence is changing not only how quickly we discover new medicines, but how precisely we can target disease. Realising that potential requires more than technology. It requires rich clinical and genomic data, a research environment that can translate insight into discovery, and regulation that advances at the pace of science. "Abu Dhabi has built that foundation. Through the Emirati Genome Programme and our connected health system, we are opening new possibilities for more precise, personalised treatments. Our collaboration with Isomorphic Labs brings together expertise in AI drug discovery and Abu Dhabi's unique strengths to accelerate the development of treatments that can benefit patients here and globally." Mr Jaderberg said: "At Isomorphic Labs, we are reimagining the entire drug discovery process from first principles with AI. The collaboration marks a critical step forward in advancing AI-driven drug discovery. We have a shared commitment to scientific innovation, with the ultimate aim of accelerating delivery of medicines to patients globally." The collaboration reflects DoH's role in enabling the responsible use of predictive and generative AI in health research. It forms part of Abu Dhabi's intelligent life sciences strategy which connects population-scale genomic and health data, research infrastructure, and regulatory pathways to accelerate the development of new medicines in the emirate. Together, the parties aim to help accelerate AI-driven discovery research, as well as broaden the evidence base for future medicines, as Middle Eastern populations have been historically underrepresented in the genomic data behind drug discovery. Meanwhile, DoH and WHOOP announced a strategic research collaboration to explore the role of continuous health insights and coaching in preventive health. The research supports Abu Dhabi's shift from reacting to illness towards personalised prevention at scale. The agreement was also signed at the Abu Dhabi Future Health Summit 2026 by His Excellency Mansoor Ibrahim Al Mansoori, and Will Ahmed, Founder and CEO of WHOOP. The collaboration will consist of a phased research programme on heart and metabolic health, exploring how wearable technology can help people better understand their bodies and take a more informed, proactive approach to their health. WHOOP continuously senses an individual's key health indicators such as sleep, recovery, strain, stress, and cardiovascular health, providing context beyond a single measurement. The first, foundational study of the24-month programme aims to assess how this continuous data, alongside coaching from WHOOP, can affect key health markers like weight, waist circumference, heart rate, blood pressure, cholesterol, blood sugar, and sleep over a six-month period for adults with obesity and high blood pressure. The study's design and oversight will be supported by physicians in Abu Dhabi. Subsequent studies will explore how WHOOP can help reduce risk factors for heart and metabolic disease by supporting the behavioural changes required alongside treatment. The programme will generate novel, real-world evidence on the role wearable technology can play in preventive and cardiometabolic health. In line with Abu Dhabi's prevention-led health agenda, the collaboration brings the continuous health data of WHOOP into the emirate's intelligent health system to accelerate population health research and safely scale new models of care. His Excellency Mansoor Ibrahim Al Mansoori said: "Our bodies can signal changes long before we feel unwell. The earlier we recognise those signals, the more we can do to protect our health. Abu Dhabi has built an intelligent health system that uses AI to turn complex health data into meaningful, personalised insights. Our partnership with WHOOP will explore how data from wearables can be translated into practical, personalised guidance, helping people better understand their health and make lasting changes." Mr Ahmed said: "This is a landmark partnership for WHOOP and Abu Dhabi. We first began working in the UAE in 2016. Since then, hundreds of thousands of citizens and residents have come to trust WHOOP to support their health and performance goals. At WHOOP, we believe deeply in what continuous data insights and coaching can offer when applied to real health challenges. Abu Dhabi puts data at the heart of how it cares for people, and I'm incredibly proud to work alongside them to explore what's possible, and even more excited about what we can accomplish together." Research will follow data governance guidelines over data minimisation, transparent data processing and secure storage, in line with applicable regulations and international best practices. Meanwhile, DoH, Cleveland Clinic Abu Dhabi, and AstraZeneca have announced a new collaboration positioning Abu Dhabi as a priority location in AstraZeneca's global clinical trial network. The collaboration leverages the emirate's intelligent health system, advanced research infrastructure and enabling regulatory environment. The collaboration will explore the feasibility of up to 30 clinical trials in Abu Dhabi by 2030 across AstraZeneca's biopharmaceutical portfolio with a focus on cardiovascular, renal and metabolic (CVRM) diseases, which are leading causes of mortality in UAE. The collaboration could deliver an estimated AED180 million (US$50 million) investment into life sciences research in Abu Dhabi by 2030. The collaboration builds on Abu Dhabi's long-term partnership with AstraZeneca in research, genomics, and digital health. It brings together DoH's role in enabling clinical research and developing Abu Dhabi's intelligent life sciences ecosystem, Cleveland Clinic Abu Dhabi's clinical and research expertise, and AstraZeneca's global R&D capabilities. Drawing on Cleveland Clinic Abu Dhabi's research infrastructure, it aims to strengthen local research capacity and generate high-quality evidence relevant to the region's health needs. The first six trials are expected to begin at Cleveland Clinic Abu Dhabi by the end of 2026. His Excellency Mansoor Ibrahim Al Mansoori, said: "Abu Dhabi has built an intelligent health system where population scale data, research infrastructure, and clinical excellence translate into better health outcomes. This collaboration brings global clinical trials into this system, supporting our ambition to create a globally recognised environment for clinical research, and strengthens the evidence base to help ensure that new medicines are developed for the diversity of the world's patients." Dr Georges-Pascal Haber, Chief Executive Officer of Cleveland Clinic Abu Dhabi, said: "By combining Cleveland Clinic clinical expertise, the Department of Health - Abu Dhabi's infrastructure, and AstraZeneca's global research capabilities, we can accelerate clinical research, expand access to innovative treatments, and generate evidence that improves patient outcomes. Together, we are strengthening Abu Dhabi's position as a leader in clinical research, with benefits for patients across the globe." Mikhail Kosiborod, Senior Vice President, Late CVRM BioPharmaceutical R&D, AstraZeneca, said: "Clinical trials play a vital role in generating high-quality evidence that advances healthcare, providing patients with early access to promising new therapies and ensuring our data is generated in diverse, representative populations. This collaboration with the Department of Health - Abu Dhabi and Cleveland Clinic will enable further investment in clinical research infrastructure, and deliver evidence that informs clinical practice, ultimately shaping the future of patient care across conditions that are the biggest public health threats, both locally and globally." The collaboration also aims to generate locally relevant evidence, drawing on Abu Dhabi's population-scale health and genomics data to help address the historical underrepresentation of regional populations in pharmaceutical research. The proposed studies will support the development of local investigators and research professionals, while creating opportunities for eligible patients to participate in international clinical research, subject to study approvals and enrolment criteria.

Tech Funding News
Oct 9th, 2026
DeepMind spinout Isomorphic Labs eyes $40B valuation less than five months after $2.1B round: Report — TFN

Isomorphic Labs is reportedly in early talks to raise at a valuation of $40B or up to $50B. The round has not closed.

N24
Sep 8th, 2026
Top VCs select 12 European biotech startups to watch as Isomorphic Labs raises $2.1B

European biotech is attracting significant venture capital as Isomorphic Labs raised $2.1 billion in its Series B round in 2026, the largest investment in AI-driven drug discovery history. This single round exceeded total VC investment in European biotech over previous multi-month periods. Top venture investors cite a maturing ecosystem across the UK, France, and Germany. Key drivers include advanced AI models accelerating clinical trials, strong academic spin-offs from European universities, and increasing participation from large American and global funds in Series A and B rounds. The funding surge reflects broader capital deployment across European deeptech sectors. Venture partners highlight that startups combining biological expertise with scalable software solutions are best positioned for sustained growth through 2026 and beyond.