Research Associate / Senior Research Associate
BreezeBio
Research Associate / Senior Research Associate
BreezeBio
CRISPR gene therapies delivered by nanoparticles
Salary Range: 80000 to 130000 (Currency: USD) (Pay period: per-year-salary)
BreezeBio is a rapidly growing, early-stage company developing a proprietary and novel delivery platform with the potential to transform genetic medicine. Our interdisciplinary team works across chemistry, payload design, formulation, screening, and preclinical research to advance our NanoGalaxy® hydrophilic nanoparticle (HNP) platform toward a pipeline of therapeutic candidates.
BreezeBio is seeking a highly motivated and technically skilled Research Associate or Senior Research Associate with substantial hands-on rodent in vivo experience to join our In Vivo team. This is a highly practical, laboratory-based position focused on the execution of in vivo studies evaluating nanoparticle-encapsulated therapeutic candidates.
The successful candidate must have direct experience independently performing routine procedures in mice and/or rats, including intravenous and intramuscular dosing, blood collection, and tissue harvests. This role is best suited for someone who is comfortable working hands-on with animals, can perform established procedures with accuracy and consistency, and can contribute to the successful execution of multiple studies in a fast-paced research environment.
The position will report to the Group Lead – In Vivo and will involve close collaboration with scientists and other functional teams across the organization.
BreezeBio fosters an exciting and dynamic environment where we value impactful data, scientific rigor, and creative solutions. We are seeking talented and motivated individuals to join our team as we expand across all functions within the organization.
Perform hands-on in vivo studies in mice and rats, including routine animal handling, dosing, blood collection, and tissue collection.
Independently perform various routes of administration, particularly intravenous (IV), intramuscular (IM), intraperitoneal (IP), and subcutaneous (SC) injections.
Perform blood collection procedures, including retro-orbital (RO) and submandibular bleeding.
Perform terminal procedures, including tissue and organ harvests, with appropriate sample processing and handling.
Assist with study planning, preparation, execution, and monitoring in collaboration with team members.
Conduct routine animal health monitoring, body weight measurements, clinical observations, and study-related assessments.
Maintain accurate and detailed experimental records and ensure proper documentation of study procedures and results.
Execute established protocols and standard operating procedures (SOPs) with accuracy, consistency, and attention to detail.
Work collaboratively with multidisciplinary teams and communicate study progress and results effectively.
Bachelor’s degree in Biology, Animal Science, Biomedical Sciences, or a related field.
At least 1 year (RA) or 3 years (Senior RA) of direct, hands-on in vivo experience working with laboratory rodents.
Demonstrated practical experience performing rodent dosing procedures, particularly IV, IM and PO administration.
Direct experience performing blood collection in rodents, particularly retro-orbital and submandibular bleeding.
Experience performing terminal procedures and tissue/organ harvests.
Strong animal handling skills and familiarity with routine animal care and monitoring.
Ability to independently perform established procedures with minimal supervision and consistently generate high-quality, reproducible data.
Strong organizational skills, attention to detail, and ability to maintain accurate laboratory records.
Ability to work effectively in a collaborative, fast-paced, multidisciplinary environment.
Excellent written and verbal communication skills.
Experience with both mouse and rat models.
Experience with pharmacokinetic (PK), pharmacodynamic (PD), and/or efficacy studies.
Experience with fibrosis models, such as pulmonary/lung fibrosis models.
Familiarity with rodent models of immunological disorders, autoimmune diseases, and/or genetic diseases.
Experience with anesthesia, perfusion, and tissue processing.
Experience working in a biotechnology or pharmaceutical research environment.
Research Associate: Bachelor’s degree with at least 1 year of direct, hands-on rodent in vivo experience.
Senior Research Associate: Bachelor’s degree with at least 3 years of direct, hands-on rodent in vivo experience, with demonstrated ability to independently execute complex in vivo procedures and studies.
This is a hands-on, animal-facing position. Candidates must have direct, practical experience performing procedures on live rodents. Experience limited to observing animal procedures, assisting with study coordination, or analyzing data from in vivo studies will not meet the technical requirements for this position.
BreezeBio develops and commercializes gene therapies and gene-editing solutions by building a CRISPR delivery system from engineered CRISPR components and a proprietary polymer nanoparticle library. Its product works by packaging Cas9 and guide RNAs into polymer nanoparticles that deliver edits to specific tissues, aiming for safer and more efficient gene knockout therapies. The company differentiates itself with an in-house, proprietary nanoparticle library combined with component-level CRISPR engineering to tailor delivery, supported by proof-of-concept data and ongoing partnerships and licenses. Its goal is to bring gene therapies to the market through licensing, partnering, and direct sales of the delivery technology and resulting therapeutics to medical and healthcare customers.
Explore more opportunities at BreezeBio