Head of AI/ML Portfolio Strategy and Operations
Posted on 3/20/2024
Flagship Pioneering

501-1,000 employees

Originates biotech ventures for health and sustainability
Company Overview
Flagship Pioneering stands out as a leader in the biotechnology industry, having originated and nurtured over 100 scientific ventures, including high-profile companies like Moderna and Indigo Agriculture. The company's culture is rooted in developing transformative products for human health and sustainability, as evidenced by their creation of platform companies like Generate Biomedicines and Tessera Therapeutics. Their competitive edge lies in their ability to explore new frontiers in genetics, as demonstrated by their recent unveiling of Quotient Therapeutics, a venture aimed at creating transformative medicines.
Venture Capital

Company Stage


Total Funding





Cambridge, Massachusetts

Growth & Insights

6 month growth


1 year growth


2 year growth

Cambridge, MA, USA
Experience Level
Desired Skills
Data Science
AI & Machine Learning
Project Management
Strategy Development
Business Development
Operations & Logistics
Business & Strategy
  • 4+ years' experience in strategy, operations, and/or product management in a top-tier management consulting firm or technology company or startup.
  • At least 2+ years' managerial experience with a track record of building an outstanding team environment and driving substantial business impact.
  • BA/BS and a MS/MA, PhD, MBA, or equivalent time spent deep in technical/scientific topics (e.g., Engineering or Data Science) from a top-tier academic institution.
  • Highly knowledgeable and passionate about latest AI/ML trends and technologies.
  • Must have strategic mindset for applying and rapidly experimenting with new AI tools.
  • Strong personal drive and enthusiasm for creating and leading operations for a world-class team of computational scientists, engineers, and entrepreneurs.
  • Must have desire for speed and agility and ability to thrive in a fast-changing entrepreneurial, technical environment.
  • Energy to build a positive and success-oriented team culture; lead by example to ensure collaboration, teamwork, open communication, constructive conflict resolution and organizational flexibility.
  • Excellent communicator in writing and speech.
  • Highly skilled in developing compelling visual slide presentations to inspire confidence in different audiences - including senior executives, investors, academic partners, and technical teams.
  • Excellent analytical, organizational and time management skills and are comfortable working independently.
  • Collaborates with the Head of Pioneering Intelligence (PI) to set organizational priorities related to AI/ML – including Flagship’s enterprise AI strategy and investments in ML capabilities to amplify Flagship’s process of creating breakthrough innovations as well as new platform companies that build on the latest AI advances.
  • Provides strategic guidance to Head of PI and origination team on developing investable thesis for each new AI/ML-focused venture.
  • Pressure tests PI’s strategic priorities and resource allocation within each venture to identify opportunities for faster and greater value creation.
  • Establishes and oversees (evolving) processes that enable most impactful contributions from PI team members (e.g., sharing best practices, creating PI-wide ability to tap into AI/ML knowledge, resources, etc.).
  • Provides guidance and coaching to PI team members to improve their productivity, deepen professional relationships, and shape/reinforce a culture of ownership, respect, and innovation.
  • Ensures that objectives and associated activities are clearly communicated to and understood by PI team members.
  • Tracks performance on goals and KPIs for PI team. Identifies issues that impact the successful execution of plans. Escalates risks and offers ideas to mitigate.
  • Adds structure and process for Pioneering Intelligence – without being overly bureaucratic – to ensure that activities run efficiently within and across teams.
  • Sets agendas and cadence for PI-wide meetings (i.e., Origination updates, team offsites), and ensures successful preparation and execution for these meetings.
  • Documents and communicate decisions and action items from meetings and ensures follow-up and closure of action items.
  • Prepares or contributes to the preparation of high-quality presentations, reports, briefings, etc. for meetings and/or communications involving the Head of PI.
  • Collaborates with the Head of PI and Finance Business Partner on annual business reviews and regular budget updates.
  • Works closely with Head of PI and HR Business Partner on recruitment and talent development initiatives.
  • Works closely with Head of PI and Director of Flagship Fellowship on end-to-end strategy and management of AI Summer Fellowship program.
  • Works closely with Head of PI and Communications Business Partner on PI’s strategy to deepen reach and relevance with external stakeholders and across Flagship ecosystem.
  • Develops and maintains strong relationships with portfolio company executives, Flagship senior leaders, and colleagues at all levels.
  • Keeps a pulse on Pioneering Intelligence team and integrates culture building into the operating model and meeting execution.
  • Oversees onboarding of all new PI employees.
  • Executes special projects or initiatives on behalf of the Head of PI.