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Recursion

Data-driven drug discovery platform leveraging datasets

Executive Director - Clinical Pharmacology/Pharmacometrics

Quantitative Biology & BiostatisticsUpdated on Nov 10
Full-timeRemote in UK

About the Job

Requirements

  • A Ph.D. in Pharmaceutical Sciences, Pharmacokinetics, or a related discipline; an M.D. with clinical pharmacology expertise; or a Pharm.D. with a clinical pharmacology fellowship, and 10 or more years of experience in biotech or pharmaceutical drug development.
  • Demonstrated success leading all clinical pharmacology-related aspects of drug development.
  • Ability to work with internal and external stakeholders to manage pharmacokinetic, pharmacokinetic-pharmacodynamic, and pharmacokinetic-safety analyses, including non-compartmental analysis, population pharmacokinetic modeling, and pharmacokinetic-pharmacodynamic modeling and simulations to support dose selection, exposure-response, and exposure-safety analyses through various phases of drug development.
  • Proficiency with WinNonlin, Monolix, NONMEM, R, or other modeling software.
  • Skills in driving collaboration, achieving results, influencing, and resolving conflicts across internal and external stakeholders.
  • Demonstrated experience responding to regulatory agency questions, preparing clinical pharmacology aspects of regulatory submissions, and attending regulatory meetings.
  • Ability to contribute effectively to a rapidly growing drug discovery and development company, with a proactive, resourceful, efficient, decisive, and results-oriented approach.

Responsibilities

  • Develop clinical pharmacology and pharmacometric strategies to accelerate and support the overall product development plan.
  • Serve as the clinical pharmacology lead for various programs in clinical development, represent the function in regulatory interactions, and propose strategies to advance therapies to patients.
  • Solve drug development questions and problems by performing or overseeing modeling and simulation with various tools to support decision-making.
  • Design clinical studies by providing clinical pharmacology input on study designs from Phase 1 through Phase 3, including dedicated Phase 1 clinical pharmacology studies.
  • Author and review clinical pharmacology sections for regulatory documents, including Investigator's Brochures, INDs, NDAs, and other regulatory submissions.
  • Act as the clinical pharmacology expert during interactions with health authorities.
  • Work with clinical study teams, translational teams covering DMPK, translational modeling and toxicology, preclinical teams, and due diligence teams to address clinical pharmacology considerations.
  • Collaborate with clinical development functions, including clinical science, clinical operations, regulatory affairs, and biostatistics, and discovery functions, including DMPK, biology, chemistry, and translational biomarkers.

Desired Qualifications

  • Experience in oncology is preferred but is not required.

About the Company

Recursion

Data-driven drug discovery platform leveraging datasets

Recursion uses a data-driven platform to speed up drug discovery in TechBio by combining large biological and patient datasets with wet-lab experiments. It runs tens of thousands of experiments weekly to profile genes and compounds across many cell types, and processes results on its BioHive 1 supercomputer to map billions of gene–compound relationships. This approach lets Recursion identify potential drug candidates by turning experimental data into actionable insights, and it collaborates through strategic partnerships with pharma companies, labs, and healthcare providers rather than pursuing traditional in-house discovery alone. Its goal is to decode biology at scale and translate findings into new medicines that help patients.

Company size
501-1,000
Company stage
IPO
Headquarters
Salt Lake City, UT
Founded
2013

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