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Roche

Global pharmaceuticals and diagnostics company

Country Medical Manager - Giredestrant

Full-TimeUpdated on 10/14/2026
No salary listed
Mid
Master's, PhD
Shanghai, China
In Person
Biology & Biotech

About the job

Requirements
  • A Master's degree or above in Clinical Medicine, Pharma, or Bioscience; Clinical Medicine is preferred.
  • At least 2 years of pharmaceutical company experience in medical-related roles; candidates with a Bioscience background need at least 3 years of such experience.
  • Customer focus in prioritizing the needs of patients and customers, including healthcare professionals and therapeutic area experts.
  • Strategic acumen to think strategically, act with autonomy, and work in complex cross-functional team environments.
  • Basic artificial intelligence literacy and a learning mindset to integrate digital tools into day-to-day work, with the ability to ensure human oversight of artificial-intelligence-derived content, including large language models.
  • Ability to collaborate effectively, show leadership, self-motivation, and accountability in a multi-skilled team, and share expertise across the organization and countries.
  • Curiosity and a growth mindset, including continuous learning, self-awareness, feedback culture, comfort navigating ambiguity, collaboration, and solution finding.
  • Ability to articulate complex medical and scientific context, inform medical guidelines by contextualizing data, build trust, and communicate directly and respectfully with internal and external stakeholders at peer level.
  • An entrepreneurial mindset, including taking calculated risks, challenging the status quo, proposing pragmatic value-adding solutions, maintaining a holistic view of patient, business, and ecosystem needs, and protecting Roche's license to operate.
  • Focus on value creation, sustainability, and impact for patients, customers, and society, considering decisions through the customer and patient lens.
Responsibilities
  • Contribute scientific, medical, and therapeutic-area expertise for relevant diseases, and act as a medical expert for pipeline and portfolio products throughout the product life cycle.
  • Lead the medical component of the integrated strategy, shape a forward-looking and scientifically differentiated local value story, and communicate Roche’s contributions across key disease areas.
  • Proactively engage top-tier therapeutic area experts and other key stakeholders in alignment with other field roles, driving pre-launch strategies and post-launch engagement to support appropriate patient treatment and access to the portfolio.
  • Establish peer-to-peer relationships with external stakeholders and develop science-driven collaborations with therapeutic area experts.
  • Provide integrated medical education and scientific information to external customers, support scientific training of internal teams, and ensure continuous medical education for points-of-patient-contact roles.
  • Conduct non-promotional international and national scientific exchanges to share relevant data and support physician confidence and clinical endorsement.
  • Design and conduct insight-generation initiatives, then analyze and translate external scientific, clinical-practice, and patient insights into strategic recommendations for the franchise team; use peer discussions and medical/scientific advisory boards as insight sources.
  • Ensure medical activities, customer engagements, research projects, and material co-creation comply with company policies, ethical standards, local regulations, Good Clinical Practice, and Good Pharmacovigilance Practice.
  • Participate in global integrated evidence plan development to incorporate China local practice and meet local regulatory and payer requirements for marketing authorization, reimbursement, and value protection.
  • Develop the local integrated evidence plan, including evidence-gap analysis for value narratives across healthcare stakeholders, patients, and caregivers, and inform cross-country evidence opportunities, strategic decisions, portfolio prioritization, and resource allocation.
  • Contribute to the local evidence strategy, identify evidence gaps, and lead or support interventional studies, non-interventional studies, investigator-initiated studies, real-world evidence and data studies, scientific projects, and other tactics to address prioritized gaps and support portfolio access.
  • Identify therapeutic area experts who can provide insights on disease burden, patient pathways, patient needs and preferences, treatment landscapes, and potential changes in standards of care; use these insights to inform evidence strategies and action plans.
  • Collaborate with Clinical Operations and Legal/Regulatory teams to support Phase I–IV clinical studies, including feasibility input, strategic site selection, selected site initiation visits, and study execution with relevant internal collaborators.
  • For selected sites, participate in the OneRoche end-to-end customer-experience loop and ensure insights from investigators, study coordinators, and nurses inform strategic planning and local evidence-gap analysis.
  • Contribute medical expertise to local Health Technology Assessment submissions and interactions, critically appraise data packages, assess transferability to real-world healthcare settings, and lead evidence-generation strategy supporting market access and patient access.
  • Use early insights to inform local evidence plans and gap analyses, validate scientific integrity, and ensure Health Technology Assessment submissions are clinically relevant and credible through stakeholder exchange.
  • Build strategic external partnerships, collect insights, identify medical and customer needs, inform disease-area strategy, and contextualize artificial-intelligence information with internal and external stakeholders.
  • Drive customer advocacy and preference through proactive end-to-end strategies, shape clinical-development strategies using insights from local medical practice, and recommend actions linked to high-value propositions for affiliate pipeline products and new indications.
  • Map relevant therapeutic area experts, especially active investigators where applicable, and engage stakeholders to support and shape new therapeutic-area ecosystems in collaboration with global medical collaboration leaders and other functions.
  • Maintain custody of Roche and competitor data and evidence with internal stakeholders to support credible communication of Roche propositions.
  • Contribute medical expertise to the local Regulatory Affairs team for Health Authority submissions and interactions to obtain, maintain, and develop product licenses.
Desired Qualifications
  • Experience in the therapeutic area is strongly preferred.

About the company

Roche is a global leader in pharmaceuticals and diagnostics. It develops medicines and diagnostic tools that help detect, monitor, and treat diseases, using research and biotechnology to drive new therapies and tests. Roche combines drug development with in-house diagnostic products to support personalized medicine, where treatments are tailored to individual patients based on test results. Its approach differs from many peers by integrating drug discovery with diagnostic capabilities and by expanding its research through strategic acquisitions (like Genentech) to strengthen its biotechnology and R&D capabilities. The company’s goal is to improve patient outcomes and healthcare worldwide by delivering reliable medicines, accurate diagnostic tests, and data-driven care.

Company Size

1-10

Company Stage

IPO

Headquarters

Basel, Switzerland

Founded

1896

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Simplify Jobs

Simplify's Take

What believers are saying

  • Enicepatide delivered 15.5% weight loss in September 2026 and 22.7% in June.
  • pTau217 can scale immediately through Roche's existing lab network and improve Alzheimer diagnostics.
  • Roche's June 2026 data and September 2026 filings signal multiple obesity shots on goal.

What critics are saying

  • Eli Lilly and Novo Nordisk dominate obesity pricing, distribution, and physician mindshare today.
  • Enicepatide remains Phase II-only; Roche starts late-stage glycemic and cardiovascular studies in 2027.
  • If enicepatide disappoints, Roche burns its $2.7 billion Carmot bet and loses obesity credibility.

What makes Roche unique

  • Roche combines pharma, diagnostics, and installed cobas labs across 4,500 U.S. instruments.
  • Elecsys pTau217 won FDA clearance on August 24, 2026, and CE marking September 7.
  • Roche controls obesity assets from Carmot and Zealand, spanning GLP-1/GIP and amylin.

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Benefits

Performance Bonus

Company News

Yahoo Finance
Oct 9th, 2026
FDA approves Roche's Tecentriq for stage III colon cancer, cutting recurrence risk by 50%

The US Food and Drug Administration has approved Roche's Tecentriq in combination with a fluoropyrimidine and oxaliplatin for adjuvant treatment of stage III deficient DNA mismatch repair colon cancer. This marks Tecentriq's twelfth approved indication in the US. The approval follows the phase III ATOMIC study, published in The New England Journal of Medicine, which demonstrated that Tecentriq plus chemotherapy reduced the risk of disease recurrence or death by 50% compared to chemotherapy alone. The 36-month disease-free survival rate was 86% with the combination versus 76% with chemotherapy alone. Nearly 25% of colon cancers are diagnosed at stage III, and almost one in three stage III patients experience recurrence within five years. This represents the first approved adjuvant immunotherapy regimen for this patient population. Roche is pursuing further regulatory filings, including with the European Medicines Agency.

Yahoo Finance
Sep 30th, 2026
Roche's enicepatide shows 22.5% weight loss in 48 weeks, challenging Eli Lilly and Novo Nordisk

Roche posted strong Phase 2 results for its weight loss drug enicepatide, showing 22.5% mean weight loss over 48 weeks. This compares favourably to Eli Lilly's Zepbound, which achieved 20.2% weight loss over 72 weeks in a separate trial. In another Phase 2 study, enicepatide demonstrated HbA1c reductions of up to 2.65 percentage points in diabetic patients after 48 weeks, compared to tirzepatide's 2.37 percentage points after 52 weeks. Despite promising results, Roche faces stiff competition from Novo Nordisk and Eli Lilly, which both have deep pipelines in development. Novo Nordisk's CagriSema is nearing approval, whilst Eli Lilly's retatrutide has posted strong Phase 3 results. Roche's revenue grew 6% year over year in the first half of the year to 30.4 billion Swiss francs.

PR Newswire
Sep 30th, 2026
Roche launches newborn screening test for SMA, SCID and sickle cell disease

Roche has launched a newborn screening test that simultaneously detects three severe genetic conditions: Spinal Muscular Atrophy, Severe Combined Immunodeficiency Disease, and Sickle Cell Disease. TIB MOLBIOL, a Roche subsidiary, developed the LightMix Newborn TREC/SMN1/HBB kit for use in countries accepting the CE mark. The test enables early detection before symptoms appear, allowing clinicians to initiate life-changing treatments sooner. Early intervention can prevent severe nerve damage in SMA, enable lifesaving bone marrow transplants for SCID, and drastically lower infant mortality in SCD through preventive measures. The IVDR-approved test provides a ready-to-use solution that integrates into existing laboratory workflows. It runs on established LightCycler systems, making it accessible for private and academic hospital laboratories across Europe.

Yahoo Finance
Sep 13th, 2026
Roche's Tam-Peli cuts death risk by 54% in Chinese SCLC trial, global phase III studies planned

Roche's collaborator MediLink has announced positive phase III results for tambotatug pelitecan (Tam-Peli) in Chinese patients with relapsed small-cell lung cancer. The TAISHAN-302 trial showed Tam-Peli reduced the risk of death by 54% compared to topotecan, with median overall survival of 13.3 versus 9.4 months. The antibody-drug conjugate also demonstrated superior progression-free survival (7.4 versus 2.8 months) and objective response rates (59.1% versus 9.7%). China's National Medical Products Administration has accepted the New Drug Application for filing. Roche is developing and commercialising Tam-Peli outside mainland China, Hong Kong and Macau, with plans to rapidly initiate global trials. The therapy has received Breakthrough Therapy Designations from both the US FDA and China CDE for relapsed small-cell lung cancer.

World Today News
Sep 8th, 2026
Tempus AI raises $600M to scale AI-enhanced liquid biopsy platform for cancer recurrence detection

Tempus AI has raised $600 million in Series C funding to scale its machine learning platform for cancer recurrence detection through liquid biopsies. The investment was led by SoftBank Vision Fund 2, with participation from Roche and Merck. Phase II trial data showed the AI-enhanced liquid biopsy analysis reduced false-negative results by 37% compared to conventional methods. The platform uses deep learning algorithms trained on over 12,000 genomic profiles to identify circulating tumour DNA fragments shed by residual cancer cells. A 2025 Nature Medicine study reported the system achieved 92% specificity in detecting minimal residual disease across breast, lung, and colorectal cancers. According to SEC filings, 45% of funds will support FDA pre-market approval trials, whilst 30% will fund global expansion into EU and APAC markets.