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Vertex Pharmaceuticals

Develops therapies for serious genetic diseases

Functional Genomics Co-op - Functional Genomics

Translational Research & Bench BiologyConfirmed live in the last 24 hours
Internship · Winter 2027Boston, MA, USA$30 - $40 /hr

About the Job

Requirements

  • Currently pursuing a master's degree or PhD in Biology, Biochemistry, Genetics, Computational Biology, or a related scientific discipline.
  • Hands-on experience with human cell culture or tissue culture is required.
  • Familiarity with fundamental molecular biology methods, including PCR and cloning, is required.
  • A strong interest in and foundational understanding of genetics, genomics, and gene-editing technologies is required.
  • Applicants must have legal authorization to work in the United States now and in the future.
  • Applicants graduating before June 2027 must remain enrolled in an advanced degree program.
  • Applicants must be available to work full-time, 40 hours per week, from January through June 2027.

Responsibilities

  • Contribute to study planning and oversee experimental activities in accordance with established protocols.
  • Collaborate with Vertex scientists to conduct experiments of varying complexity using disease-relevant human cell models, analyze the resulting data, and summarize key findings.
  • Maintain thorough, accurate records of methods, observations, and results in an electronic laboratory notebook.
  • Present results and key conclusions clearly to the Functional Genomics team and cross-functional project partners.
  • Generate gene-edited cellular models, develop disease-relevant assays, and execute experiments that drive target validation and mechanism-of-action studies.
  • Perform cellular screening experiments, evaluate compound activity using flow cytometry and high-content imaging, and analyze data to guide project decisions.
  • Analyze and interpret experimental results and contribute to advancing therapeutic programs.

Desired Qualifications

  • Experience with flow cytometry is highly preferred.
  • Experience using CRISPR-Cas9 for gene editing is preferred.
  • Experience generating, maintaining, and characterizing mammalian cell lines, including clonal cell-line isolations and cell-line validations, is preferred.

About the Company

Vertex Pharmaceuticals

Develops therapies for serious genetic diseases

Vertex Pharmaceuticals develops medicines for serious diseases, with a focus on cystic fibrosis. It conducts extensive research and partners with other biotech firms to discover and develop new therapies, including ex vivo engineered cell treatments. Its products, such as ivacaftor, treat cystic fibrosis and other therapies undergo clinical testing to expand the pipeline. Revenue comes from selling approved drugs and from licensing and collaboration agreements. The company distinguishes itself through deep R&D investment, strategic partnerships, and a global reach aimed at addressing unmet medical needs. The overall goal is to bring effective new drugs to patients worldwide and improve outcomes and quality of life.

Company size
5,001-10,000
Company stage
IPO
Headquarters
Boston, MA
Founded
1989

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