Director – HR Business Partner @ 4D Molecular Therapeutics

At 4D Molecular Therapeutics, Inc. (“4DMT”), we boldly innovate to unlock the full potential of genetic medicines for countless patients. We are committed to breaking boundaries and daring to cure as we develop new and foundational products and product components through our growing technology platforms.

4DMT is a clinical-stage biotherapeutics company harnessing the power of directed evolution for targeted genetic medicines. We seek to unlock the full potential of gene therapy using our platform, Therapeutic Vector Evolution (TVE), which combines the power of directed evolution with our approximately one billion synthetic AAV capsid-derived sequences to invent evolved vectors for use in our products. We believe key features of our targeted and evolved vectors will help us create targeted product candidates with improved therapeutic profiles. These profiles will allow us to treat a broad range of large market diseases, unlike most current genetic medicines that generally focus on rare or small market diseases.

We have built a deep portfolio of AVV-based gene therapy product candidates, with five product candidates in clinical trials: 4D-150 for the treatment of wet age-related macular degeneration (wet AMD) and diabetic macular edema (DME), 4D-710 for the treatment of cystic fibrosis lung disease, 4D-310 for the treatment of Fabry disease cardiomyopathy, 4D-125 for the treatment of X-linked retinitis pigmentosa (XLRP), and 4D-110 for the treatment of choroideremia. In addition, we have two product candidates in preclinical studies: 4D-175 for geographic atrophy (GA) and 4D-725 for alpha-1 antitrypsin deficiency.

To-date, we have demonstrated clinical proof-of-concept for three evolved vectors in three therapeutic areas and routes of administration with five products and patient populations. We believe this validates the power of our directed evolution platform for discovering superior vectors compared to wildtype viral vectors. We have built a robust and efficient product engine with 6 open Investigational New Drug Applications (INDs) in the U.S., 1 IND in Taiwan, and 1 Clinical Trial Approval (CTA) in Australia. We believe we are positioned to create, develop, manufacture and, if approved, effectively commercialize targeted genetic medicines that could transform the lives of patients suffering from debilitating diseases.

In addition to TVE, our technology includes a robust AAV manufacturing platform and onsite manufacturing facility that allows us to rapidly produce and test research grade material and scale up to GMP clinical material. This internal capability and close collaboration between our R&D and Manufacturing teams has greatly accelerated the pace of discovery at 4DMT.

Company Differentiators:

• Fully integrated clinical-phase company with internal manufacturing
• Demonstrated ability to move rapidly from idea to IND
• Five candidate products in the clinic and two declared pre-clinical programs
• Robust technology and IP foundation, including our TVE and manufacturing platforms
• Initial product safety and efficacy data substantiates the value of our platforms
• Opportunities to expand to other indications and modalities within genetic medicine

GENERAL SUMMARY:

We are excited to have an experienced Director, HR Business Partner join our amazing HR team at 4D Molecular Therapeutics! This role is critical to our continued success and will be responsible for partnering with employees and managers to execute on 4D’s people strategies in areas of organizational development, change management, employee engagement, employee relations, and performance management. In this role, you will consult, advise, coach, influence, innovate and challenge our leaders and individual contributors on people-related issues. This role will partner with the VP, HR and functional leaders to further develop and drive HR initiatives to improve the effectiveness of the organization as whole, provide recommendations that will enhance management capability, employee retention, and positively impact overall organizational performance.

RESPONSIBILITIES:

Partner with VP, HR and senior leadership to develop and implement effective HR policies and practices that will support the strategic growth of a business
Coach and consult line managers in all issues regarding people management, HR practices, policy, employment law, employment relations, change and performance management, etc.
Educate, coach, and partner with managers on performance management and employee development and career goals
Provide timely information and/or education for all levels of a company on HR issues
Lead and support management in organizational assessment, talent gap analysis, organization structure to turn business strategies into action
Develop people strategies and design approaches for diagnosing and enhancing organizational effectiveness and employee satisfaction
Participate in our talent calibration process with VP, HR and leadership
Lead all Learning & Development initiatives and strategy to work on value-added programs in areas of training, development, career mobility, and job performance for our employees
Work in partnership with VP, HR on projects related to employee engagement and retention
Consult with key organizational stakeholders to identify and diagnose organizational problems and design and help implement innovative and sustainable solutions
Consult with VP, HR and Leadership to identify strategies that support the desired organizational culture across 4D while also connecting to specific needs of individual functional areas
Collaborate with the HR team to champion and accelerate a culture of excellence in which people feel engaged and inspired to deliver top business results
Identify opportunities and help shape strategies and plans to address gaps
Design and lead the DEI efforts and strategy at the company
Help drive adoption and consistency of HR programs with special emphasis on Diversity and Inclusions initiatives
Stay current on trends in the HR field to ensure solutions are progressive and relevant
Participate and collaborate with HR team in the continual development of HR programs, such as recruiting, retention, compensation, benefits, and other programs
Perform other duties as necessary and assigned

QUALIFICATIONS:

Education:

Bachelor’s degree

Experience:

Requires 10+ years of HR experience, with at least 5 years in a Business Partner role
Requires experience working in a publicly traded company and within the Life Sciences industry.

Skills:

Sound business acumen
Required excellent skills in developing effective presentations in PowerPoint.
Excellent judgment in handling confidential, sensitive information.
Effective interpersonal skills to collaborate effectively and build strong relationships
Self-driven with the ability to prioritize and multitask
Ability to work and communicate with employees at many levels across diverse cultures
Excellent judgment in handling confidential, sensitive information
Excellent overall communication, writing and organizational skills
Extensive knowledge of Federal, California, other state and local legal regulations related to employment and HR policies.
Experience with HRIS (preferably ADP), Microsoft Suite tools (including Outlook, PowerPoint, Word, and Excel), benefits administration and compensation tools.

Base salary compensation range:

Bay Area Range: $208,000 - $251,000

Please note, the base salary compensation range and actual salary offered to the final candidate depends on various factors: candidate’s geographical location, relevant work experience, skills, and years of experience

4DMT provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, gender, sexual orientation, national origin, age, disability, genetic information, marital status, status as a covered veteran, and any other category protected under applicable federal, state, provincial and local laws.

Equal Opportunity Employer/Protected Veterans/Individuals with Disabilities

Compensation Overview

6 month growth

1 year growth

2 year growth