U

University of Kansas Medical Center

Health sciences campus in Kansas City, KS

Technical Director - Preclinical Imaging Core

Full-Time
$103k - $164.8k
Mid
PhD
Kansas City, MO, USA
In Person
Academic & Institutional ResearchLife Sciences Research

About the job

Requirements
  • A Ph.D. or equivalent in Biomedical Engineering, Medical Physics, Imaging Science, Physics, Chemistry, Chemical Engineering, Bioengineering, Neuroscience, Cancer Biology, or a closely related discipline.
  • Three years of experience in preclinical biomedical imaging and research, including expertise in at least one advanced imaging modality; designing, conducting, and analyzing preclinical imaging studies; operating and troubleshooting sophisticated biomedical imaging instrumentation; and working with small-animal models, including animal preparation, anesthesia, physiological monitoring, and longitudinal imaging studies.
  • Maintain awareness of advances in preclinical imaging, image analysis, and related technologies.
  • Conduct activities professionally and ethically, in accordance with institutional policies and applicable local, state, and federal laws and regulations.
  • Perform job responsibilities safely and securely.
  • Develop and maintain job-specific knowledge and skills to keep pace with industry changes.
Responsibilities
  • Direct the day-to-day scientific and technical operations of the Preclinical Imaging Shared Resource under the supervision of its Director.
  • Develop, optimize, validate, and maintain advanced preclinical imaging protocols.
  • Consult with investigators on imaging modality selection, experimental design, longitudinal study design, quantitative endpoints, and image analysis.
  • Develop reproducible quantitative imaging workflows and imaging biomarkers.
  • Promote integration of MRI, micro-CT, optical imaging, photoacoustic imaging, and other complementary imaging technologies.
  • Evaluate emerging imaging technologies and recommend strategic implementation within the Shared Resource.
  • Supervise postdoctoral fellows and other scientific or technical personnel as assigned by the Shared Resource Director.
  • Coordinate day-to-day scientific activities and establish priorities for Shared Resource staff.
  • Train graduate students, postdoctoral fellows, research staff, faculty investigators, and authorized users in imaging methodologies and appropriate instrument operation.
  • Ensure users demonstrate appropriate competency before independent instrument use where applicable.
  • Oversee scientific operation, performance monitoring, and routine quality assurance of imaging instrumentation.
  • Develop and maintain standard operating procedures for imaging systems and experimental workflows.
  • Troubleshoot technical problems and coordinate with institutional personnel, manufacturers, and service engineers when necessary.
  • Maintain documentation of instrument performance, maintenance, calibration, and quality-control procedures.
  • Participate in planning for equipment upgrades, new instrumentation, software implementation, and facility expansion.
  • Assist the Shared Resource Director with strategic planning for future imaging capabilities.
  • Lead technical implementation and validation of next-generation MRI capabilities, including the forthcoming 18.8 Tesla MRI platform.
  • Develop and optimize high-field and ultra-high-field MRI protocols for preclinical applications.
  • Establish reproducible workflows for quantitative and longitudinal MRI.
  • Facilitate integration of MRI and NMR spectroscopy with optical imaging, micro-CT, photoacoustic imaging, and other complementary technologies.
  • Support development of advanced image reconstruction, quantitative analysis, and AI-assisted imaging pipelines.
  • Meet with investigators to define imaging objectives and develop technically rigorous experimental plans.
  • Support interdisciplinary cancer research involving tumor biology, therapeutic response, immunotherapy, drug delivery, pharmacokinetics, and related areas.
  • Participate in collaborative NIH-, DoD-, NSF-, foundation-, and industry-funded research projects.
  • Assist investigators in developing imaging components of grant applications, including experimental design, feasibility assessment, methodology, and resource descriptions.
  • Contribute scientific expertise to manuscripts, abstracts, presentations, and other scholarly products arising from Shared Resource-supported research.
  • Participate in collaborative research leading to development of new imaging technologies and methodologies.
  • Oversee and participate in imaging studies involving murine and other approved preclinical disease models.
  • Ensure appropriate procedures for animal preparation, anesthesia, physiological monitoring, recovery, and longitudinal imaging.
  • Ensure imaging activities comply with approved IACUC protocols, institutional biosafety requirements, and applicable University and Cancer Center policies.
  • Maintain required institutional training and ensure supervised personnel maintain appropriate training and compliance.
  • Assist the Shared Resource Director in developing and implementing operational policies for the Shared Resource.
  • Help coordinate instrument access, project prioritization, training, and efficient utilization of Shared Resource resources.
  • Monitor technical aspects of ongoing projects and identify potential operational or scientific barriers.
  • Participate in preparation of Shared Resource reports, Cancer Center Support Grant documentation, instrumentation proposals, and other institutional reporting as requested by the Director.
  • Participate in Shared Resource advisory activities and interactions with institutional leadership, collaborators, donors, and external stakeholders as appropriate.
  • Represent the Shared Resource at scientific meetings, institutional committees, seminars, and other professional activities when requested by the Director.
  • Contribute to maintaining the Shared Resource as a state-of-the-art, scientifically rigorous, collaborative imaging resource supporting the research mission of the University of Kansas Cancer Center.
  • Participate in departmental seminars, Shared Resource meetings, and relevant Cancer Center activities.
  • Perform other duties as assigned by the Shared Resource Director.
  • Coordinate work with other University areas to ensure integration and support of the University mission.
  • Participate in relevant committees, task forces, or similar activities.
Desired Qualifications
  • Preclinical MRI experience, particularly high-field or ultra-high-field MRI.
  • Experience with Bruker MRI systems and ParaVision.
  • Experience with MRI pulse sequence development, optimization, and troubleshooting.
  • Experience with quantitative MRI and development of imaging biomarkers.
  • Experience with micro-CT.
  • Experience in optical imaging.
  • Experience in photoacoustic imaging.
  • Experience with PET or SPECT.
  • Experience with multimodal image registration and quantitative image analysis.
  • Experience with artificial intelligence or machine learning for biomedical imaging.
  • Experience using Python, MATLAB, C++, or related scientific programming environments.
  • Experience with cancer biology, immunology, drug development, or neuroscience applications of imaging.
  • Experience in management or operation of a shared research resource or biomedical imaging facility.
  • Experience developing standard operating procedures, quality assurance programs, and reproducible imaging workflows.
  • Experience with collaborative NIH-, DoD-, NSF-, or other federally funded research.
  • Experience preparing instrumentation or research grant applications.

About the company

U

University of Kansas Medical Center

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University of Kansas Medical Center is the University of Kansas academic health sciences campus in Kansas City, Kansas. Its schools provide degree-granting education in health professions, medicine, and nursing.

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