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Heartflow reported second quarter 2026 revenue of $64.1 million, up 48% year-over-year, driven by increased US case volumes for its FFRCT and Plaque products. The AI-powered coronary artery disease diagnostics company posted a gross margin of 83.0% and a net operating loss of $17.9 million. The company raised its full-year revenue guidance to $246 million to $250 million, representing approximately 40% to 42% growth, up from previous guidance of $228 million to $232 million. It also increased its non-GAAP gross margin outlook to approximately 82% from 81%. CEO John Farquhar said the Plaque product is emerging as a "meaningful second growth engine" alongside the core FFRCT business, helping win new accounts and deepen physician utilisation.

HeartFlow reported second quarter 2026 revenue of $64.1 million, up 48% year over year. US revenue grew 51% to $59.6 million, marking the company's fastest growth in eight quarters. The medical technology firm's Plaque product generated $7.8 million in revenue, exceeding expectations. Total global revenue cases reached 84,491, up 74% year over year. Gross margin expanded to 83.3% from 75.6% in the prior year period, driven by AI efficiencies and higher-margin Plaque mix. HeartFlow raised its full-year 2026 revenue guidance to $246 million to $250 million, representing 40% to 42% growth. The company also increased its Plaque revenue outlook to $29 million to $31 million. The non-GAAP operating loss narrowed to $7.9 million from $11.5 million last year. HeartFlow ended the quarter with $246.8 million in cash and investments.

Heartflow (NASDAQ:HTFL) shares gap up following better-than-expected earnings. August 14, 2026 Key points. * Heartflow shares surged after the company reported adjusted EPS of $(0.07), beating estimates of $(0.22), while quarterly revenue reached $64.08 million, up 47.7% year over year. * The stock opened at $39.06 versus a prior close of $31.01 and last traded near $41.07, above the analyst consensus target of $38.86. * Analysts maintain a generally positive outlook, with MarketBeat reporting a "Moderate Buy" consensus, although insiders have sold 115,805 shares worth approximately $3.53 million over the past three months. * Interested in Heartflow? Here are five stocks we like better. Heartflow, Inc. (NASDAQ:HTFL - Get Free Report) shares gapped up prior to trading on Friday following a stronger than expected earnings report. The stock had previously closed at $31.01, but opened at $39.06. Heartflow shares last traded at $41.0730, with a volume of 1,793,589 shares changing hands. The company reported ($0.07) EPS for the quarter, beating analysts' consensus estimates of ($0.22) by $0.15. The company had revenue of $64.08 million for the quarter. The company's revenue for the quarter was up 47.7% on a year-over-year basis. Wall Street analyst weigh in. A number of research firms have recently commented on HTFL. Piper Sandler reissued an "overweight" rating on shares of Heartflow in a research note on Friday. Canaccord Genuity Group decreased their target price on Heartflow from $43.00 to $37.00 and set a "buy" rating for the company in a research note on Friday, May 15th. Freedom Capital upgraded shares of Heartflow to a "strong-buy" rating in a research report on Tuesday, June 30th. William Blair started coverage on shares of Heartflow in a report on Monday, May 4th. They issued an "outperform" rating for the company. Finally, Weiss Ratings raised shares of Heartflow from a "sell (e+)" rating to a "sell (d-)" rating in a research note on Friday, August 7th. One analyst has rated the stock with a Strong Buy rating, eight have given a Buy rating, two have assigned a Hold rating and one has issued a Sell rating to the stock. According to data from MarketBeat, Heartflow presently has an average rating of "Moderate Buy" and an average target price of $38.86. Insider buying and selling at Heartflow. In other news, CEO John C.M. Farquhar sold 22,562 shares of the company's stock in a transaction on Monday, August 10th. The stock was sold at an average price of $28.31, for a total transaction of $638,730.22. Following the completion of the sale, the chief executive officer directly owned 436,280 shares of the company's stock, valued at $12,351,086.80. This represents a 4.92% decrease in their ownership of the stock. The sale was disclosed in a document filed with the SEC, which is available at the SEC website. The transaction was executed under a pre-arranged Rule 10b5-1 trading plan. Also, insider Campbell Rogers sold 9,219 shares of the stock in a transaction on Monday, May 18th. The shares were sold at an average price of $28.34, for a total value of $261,266.46. Following the completion of the transaction, the insider owned 78,731 shares of the company's stock, valued at $2,231,236.54. This trade represents a 10.48% decrease in their position. The disclosure for this sale is available in the SEC filing. The transaction was executed under a pre-arranged Rule 10b5-1 trading plan. Over the last three months, insiders have sold 115,805 shares of company stock valued at $3,530,609. Corporate insiders own 7.70% of the company's stock. Institutional trading of Heartflow. A number of hedge funds have recently bought and sold shares of HTFL. TrueMark Investments LLC raised its holdings in shares of Heartflow by 1.4% during the first quarter. TrueMark Investments LLC now owns 26,885 shares of the company's stock valued at $654,000 after acquiring an additional 379 shares during the period. Caitong International Asset Management Co. Ltd purchased a new position in Heartflow during the 4th quarter worth approximately $27,000. Strs Ohio grew its position in Heartflow by 35.3% during the 1st quarter. Strs Ohio now owns 4,600 shares of the company's stock worth $112,000 after purchasing an additional 1,200 shares in the last quarter. Russell Investments Group Ltd. acquired a new stake in Heartflow during the 4th quarter valued at $45,000. Finally, Legal & General Group Plc purchased a new stake in shares of Heartflow in the third quarter valued at $59,000. Heartflow price performance. The company has a market cap of $3.52 billion and a PE ratio of -13.18. The stock has a fifty day moving average price of $28.80 and a 200-day moving average price of $27.70. Heartflow company profile. HeartFlow, Inc NASDAQ: HTFL is a medical technology company that develops non-invasive diagnostic solutions for coronary artery disease. The company's core offering translates coronary CT angiography (CTA) data into a patient-specific, three-dimensional physiological model of the coronary arteries. Using advanced image processing and computational modeling, HeartFlow's analysis estimates fractional flow reserve (FFR) values throughout the coronary tree to identify ischemia-producing lesions without the need for invasive pressure-wire measurements. HeartFlow's cloud-based service integrates with clinical workflows: clinicians submit coronary CTA images and receive a detailed, color-coded 3D map and report that highlights lesion-specific FFR values and physiological impact. This instant news alert was generated by narrative science technology and financial data from MarketBeat in order to provide readers with the fastest reporting and unbiased coverage. 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