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Hovione

CDMO for complex drug APIs manufacturing

Modelling & PAT Scientist

Bioprocess & BiomanufacturingConfirmed live in the last 24 hours
Full-timeLisbon, PortugalNo salary listedIn-person

About the Job

Requirements

  • A university or equivalent qualification in an Engineering or scientific field is mandatory.
  • Typically, 3–5 years of relevant experience in a production environment, preferably within the pharmaceutical industry, or a PhD degree in a relevant scientific field is required.
  • Strong understanding and knowledge of process modelling, simulation principles, Process Analytical Technology (PAT), and statistical tools, including chemometrics.
  • Fluency in English is required.
  • Computer literacy and good working knowledge of Microsoft Office and relevant modelling software, including Python, MATLAB, SIMCA, and JMP, are required.
  • The candidate must have the knowledge, experience, and skills to conduct tasks in accordance with established rules and procedures.

Responsibilities

  • Suggest, develop, and implement process analytical tools to improve company efficiency in Drug Substance, Drug Product Intermediate, and Drug Product.
  • Oversee and qualify implementation of these tools in manufacturing assets in compliance with legislation and Quality, Health, Safety, and Environment (HSE) and current Good Manufacturing Practice (cGMP) policies.
  • Ensure modelling practices and methodologies align with the state of the art.
  • Promote scientific excellence and innovation in Modelling and PAT, and contribute technical expertise to expand intellectual property, product, and technology portfolios.
  • Provide process analytical and statistical technical support in projects, ensuring execution, customer satisfaction, and achievement of established objectives.
  • Increase process knowledge of unit operations through mechanistic modelling during process development and provide mechanistic modelling support for unit operations during development projects.
  • Successfully implement PAT tools and practices.
  • Participate in technology transfer and scale-up of projects to the Pilot Plant and manufacturing areas.
  • Participate in the design and development of batch and continuous manufacturing processes.
  • Write reports from research and development campaigns and cGMP manufacturing.
  • Promote best practices, innovation, and knowledge sharing within the company.
  • Promote the company through presentations at conferences and to customers, and identify patent and publication opportunities.
  • Plan and deliver assigned tasks on time, safely, efficiently, reliably, and cost-effectively.
  • Propose improvements to the area and solve problems.
  • Make quality and timely decisions within assigned Modelling and PAT tasks.
  • Gather relevant data to inform decision-makers regarding complex issues.
  • Perform professional activities in compliance with cGMP and HSE guidelines and internal and external requirements, and promote implementation and maintenance of company policies, systems, and procedures, including COPs, HBR, and SOPs.
  • Carry out assigned tasks safely, in accordance with instructions, and in compliance with environmental, health, and safety rules, procedures, regulations, and codes of practice.

Desired Qualifications

  • A PhD degree is preferred.

About the Company

Hovione

CDMO for complex drug APIs manufacturing

Hovione is a contract development and manufacturing organization that creates and scales active pharmaceutical ingredients (APIs) for medicines. It handles complex chemistry and specializes in processes like particle engineering and spray drying to improve drug absorption. It differentiates itself through a long history of tackling difficult compounds, deep manufacturing expertise, and an FDA-inspected global footprint across Portugal, Ireland, China, and the US. Its goal is to help drug developers bring new medicines to market efficiently by providing high-quality, scalable manufacturing and expanding capacity, especially in the U.S.

Company size
1,001-5,000
Company stage
Not listed
Total funding
Not listed
Headquarters
Loures, Portugal
Founded
1959

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