Full-Time

AI/ML Scientist/Developer

Axle

Axle

201-500 employees

Translational research informatics and data science

Compensation Overview

$100k - $130k/yr

Bethesda, MD, USA

In Person

On-site role at NIH in Bethesda; no remote work.

PhD

Category
AI & Machine Learning (1)
Required Skills
Scikit-learn
Python
TensorFlow
R
PyTorch
Machine Learning

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Requirements
  • PhD in computer science, engineering, applied mathematics, or a related field with demonstrated experience in AI/ML model development
  • Strong programming skills in Python, R, or similar languages are required, along with experience with machine learning frameworks such as TensorFlow, PyTorch, or scikit-learn
  • Previous experience applying computational methods in biological laboratory settings is necessary, with knowledge of experimental design principles and biological data types
Responsibilities
  • The successful candidate will design and implement machine learning models that predict organoid development outcomes based on protocol parameters, environmental conditions, and molecular characterization data
  • They will develop in silico models that can simulate organoid growth dynamics and identify optimal conditions for reproducible organoid generation
  • The role involves creating feedback loops between experimental validation and computational prediction to iteratively improve protocol standardization
  • Collaboration with experimental teams to design validation experiments and with data scientists to integrate multi-modal datasets will be essential components of this position
Desired Qualifications
  • Experience with organoid systems or tissue engineering applications is highly desirable
  • Knowledge of differential equations, systems biology modeling, and experience with deep learning approaches for biological applications will be considered strong assets
  • Familiarity with cloud computing platforms and containerization technologies is preferred

Axle Informatics provides specialized informatics solutions for translational research, health informatics, and data science to biomedical research centers and healthcare organizations. Its offerings are customized software and data management platforms that help researchers collect, integrate, analyze, and visualize large research datasets, with end-to-end tools that automate data aggregation and deliver analytics, dashboards, and decision-support features. The company differentiates itself with an integrated, scientifically informed approach that bridges data science with application development, specifically focused on translational research and clinical data work rather than generic software. Axle’s goal is to advance public health by moving biomedical discoveries from the lab to bedside, improving healthcare outcomes.

Company Size

201-500

Company Stage

N/A

Total Funding

N/A

Headquarters

Rockville, Maryland

Founded

2002

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Simplify Jobs

Simplify's Take

What believers are saying

  • NIH awarded Axle the $11.2 million N3C Dynamic Workspaces task order on September 30, 2025.
  • NCATS extended Axle through June 27, 2026, signaling trust during transition risk.
  • SK pharmteco partnered with Axle and NIH on rare-disease gene therapy programs on May 7, 2026.

What critics are saying

  • Axle depends heavily on NIH funding; one recompete failure hits revenues by 2027.
  • NCATS limited-source notices in 2025-2026 show mission-critical work gets rebid fast.
  • A larger integrator like Dovel or Leidos can underprice Axle and compress margins.

What makes Axle unique

  • Axle embeds inside NIH, winning NCATS and NIAID support work in 2025-2026.
  • Its translational-research niche blends biomedical science, software engineering, and federal program management.
  • Repeated sole-source extensions show NIH treats Axle as operational infrastructure, not a commodity vendor.

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Benefits

Health Insurance

Dental Insurance

Vision Insurance

Paid Vacation

Paid Holidays

401(k) Company Match

Educational Benefits for Career Growth

Employee Referral Bonus

Flexible Spending Accounts

Company News

TheGWW.com
Jul 25th, 2023
“Octo awarded $64.7M IT Infrastructure Call Order to support NCI’s Cancer research”

Octo, in partnership with Unissant, Axle Informatics, and TRex, has been awarded an IT Infrastructure and Operations Call Order to support the NCI’s OCIO.

GlobeNewswire
Jan 12th, 2023
Digital Pathology Market Worth $1.86 Billion by 2030 -

For instance, in May 2020, Indica Labs (U.S.), a provider of digital pathology solutions, collaborated with information technology consulting companies, Octo (U.S.) and Axle Informatics (U.S.) and the National Institutes of Health (NIH) (U.S.), to develop an online collection of high-resolution histopathology images of tissues from COVID-19 patients using Indica’s HALO Link platform.