Full-Time

Senior Product Manager

Platform & Integrations

Updated on 8/20/2026

Lirio

Lirio

51-200 employees

Behavioral-AI health engagement personalisation engine

Compensation Overview

$150k - $180k/yr

No H1B Sponsorship

Remote in USA

Remote

Remote within the US; first week onsite at a Tennessee office, with travel expenses paid.

Category
Product (1)
Required Skills
Data Science
Product Management
Machine Learning
CRM
Data Engineering
Electronic Health Records (EHR)
Observability
REST APIs
HIPAA
Data Analysis

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Requirements
  • 7+ years of progressive product management experience, including ownership of complex enterprise platforms, integrations, or other technically sophisticated products, with demonstrated success setting strategy, influencing senior stakeholders, navigating product and architectural trade-offs, and delivering scalable capabilities across clients or markets.
  • A proven track record of leading complex platform initiatives from discovery through delivery with measurable impact on adoption, scalability, and business outcomes.
  • Strong product fundamentals, including discovery, requirements definition, outcomes-driven prioritization, success metrics, and using data to validate assumptions and demonstrate impact.
  • Strong systems thinking and decision-making rigor, with the ability to reason across interconnected platforms, data, and integrations, weigh trade-offs against evidence, and make sound calls in ambiguous, high-stakes situations.
  • Proven ability to set technical product direction that is adopted across multiple teams, influencing without direct authority.
  • Strong communication skills for distilling complex technical ideas for technical and non-technical audiences, including senior executives.
  • Comfort understanding system architecture, integration patterns, data models, event-driven workflows, identity resolution, analytics, and technical constraints.
  • Skilled negotiation, including challenging assumptions and pushing back on competing demands while keeping stakeholders aligned around the best product decision.
  • All applicants must be authorized to work in the United States without sponsorship.
Responsibilities
  • Envision, articulate, and deliver the platform strategy and product bets that shape the company's position in the healthcare market.
  • Develop an understanding of customer and business challenges, market dynamics, and emerging opportunities by engaging customers and stakeholders, monitoring regulatory and policy developments, and participating in industry forums, then use those insights to shape product strategy.
  • Evaluate information from multiple sources and apply systems thinking to prioritize across competing demands and make evidence-based trade-offs.
  • Own decisioning and orchestration capabilities as products, defining how behavioral and artificial-intelligence-driven intelligence becomes coordinated, personalized interventions across clients' existing channels.
  • Own the healthcare integration layer, including integrations with electronic health records, health information exchanges, customer relationship management systems, digital experience platforms, and content management systems, using standards-based interoperability such as Fast Healthcare Interoperability Resources, Health Level Seven International, and IAL2.
  • Lead the build-out of partner-platform integrations, assess technical fit, define and prioritize integration requirements, and drive them through delivery.
  • Define product requirements for data flows, event-driven workflows, identity, consent, and analytics, and make product and architectural trade-offs with engineering.
  • Keep the platform reliable, interoperable, extensible, and scalable across healthcare verticals and enterprise environments.
  • Build cross-functional partnerships with Engineering, Architecture, Data Science, Artificial Intelligence/Machine Learning, Behavioral Science, Design, Analytics, Security, and Client Success to align teams and translate opportunities into requirements and scalable platform capabilities.
  • Lead through influence across organizational boundaries, build consensus among senior stakeholders, align competing priorities around platform outcomes, and guide complex product, technical, and business trade-offs.
  • Serve as a senior product voice with clients, partners, and executives by shaping understanding of platform strategy, making recommendations, surfacing risks and dependencies, and challenging requests and assumptions when evidence or long-term product value requires it.
  • Define, monitor, and ensure product metrics tie platform investment to company-level outcomes across product adoption, operational, engagement, and health-outcome measures, while unlocking scalable revenue opportunities.
  • Embed healthcare compliance, security, and responsible artificial intelligence into every stage of the product lifecycle.
Desired Qualifications
  • Understanding of the healthcare market and buyers, including payers, providers, employers, and retail health.
  • Experience defining or delivering partner, third-party, or platform integrations.
  • Demonstrated thought leadership in healthcare platforms, interoperability, or applied artificial intelligence.
  • Experience with REST APIs, Model Context Protocols, and other integration patterns.
  • Experience with healthcare data and interoperability, including Fast Healthcare Interoperability Resources, Health Level Seven International, electronic health records, pharmacy data, or claims data.
  • Experience with cloud-based and event-driven platforms.
  • Experience with data pipelines, reporting, experimentation, and measurement.
  • Experience with identity, consent, privacy, and preference management.
  • Experience with enterprise scalability, reliability, observability, and security.
  • Familiarity with healthcare data and regulatory requirements.
  • Experience in healthcare, digital health, payer/provider, retail health, or life sciences.
  • Experience with artificial-intelligence/machine-learning-enabled or intelligence products.
  • Familiarity with the Health Insurance Portability and Accountability Act, protected health information/electronic protected health information, or regulated environments.
  • Startup or high-growth company experience.

Lirio uses behavioral science and AI to improve patient engagement and health outcomes. Its Precision Nudging personalisation engine analyzes individual behaviors, communication patterns, and social/clinical context to deliver hyper-personalized messages and interventions that encourage adherence and screenings. By moving beyond demographics, it enables real-time, one-to-one outreach to sustain engagement across care journeys, partnering with health systems, payers, and provider organizations. The goal is to reduce gaps in care and lower total cost of care by guiding patients through their evolving healthcare journey.

Company Size

51-200

Company Stage

N/A

Total Funding

$33.1M

Headquarters

Knoxville, Tennessee

Founded

2017

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Simplify Jobs

Simplify's Take

What believers are saying

  • October 2025 Precision Nudging for Life Sciences opened a larger pharma market.
  • Cone Health plans five Lirio interventions, showing repeatable enterprise adoption.
  • 2024 Nashville expansion and leadership hires signaled operational scaling beyond Knoxville.

What critics are saying

  • Lirio still lacks visible scaled revenue, despite 2026 seed filings and product launches.
  • Life-sciences messaging faces crowded competition from Salesforce, Veeva, and patient-support vendors.
  • If pharma pilots stall, Lirio's niche platform becomes a services-heavy science project.

What makes Lirio unique

  • Precision Nudging pairs behavioral science with agentic AI and omnichannel activation.
  • Lirio expanded from health systems into life sciences in October 2025.
  • Bon Secours Mercy Health remains a strategic anchor and board-level investor.

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Benefits

Health Insurance

Dental Insurance

Vision Insurance

Life Insurance

Disability Insurance

401(k) Company Match

10 paid holidays + holiday week company closure

Unlimited Paid Time Off

Hybrid Work Options

Growth & Insights and Company News

Headcount

6 month growth

0%

1 year growth

1%

2 year growth

1%
Business Wire
Feb 5th, 2026
Life sciences firms struggle with patient engagement as 70% cite adherence challenges costing $100B annually

Lirio, a behavioural science and AI platform, has released research revealing that traditional personalisation approaches in life sciences fail to improve patient engagement. The survey of over 75 life sciences executives, conducted by Sage Growth Partners, found that more than 70% identified clinical trial engagement and medication adherence as persistent challenges. The report highlights that nearly 50% of patients don't take medications as prescribed, contributing to $100 billion in annual preventable healthcare costs and 125,000 avoidable deaths. Despite growing direct-to-consumer strategies, only half of organisations use digital health technologies for patient engagement, and fewer than 3% partner with specialised vendors. The findings come as new regulations reshape pharmaceutical advertising, prompting life sciences companies to rethink patient engagement strategies beyond traditional mass messaging approaches.

Teknovation.biz
May 5th, 2025
Lirio Releases Report Titled (Re)Defining Personalization

Lirio, the Knoxville-based pioneer in the union of behavioral science and artificial intelligence to deliver better health outcomes, has released new industry findings on the significant impact that advanced health... The post Lirio releases report titled (Re)defining Personalization appeared first on Teknovation.biz.

U.S. Securities and Exchange Commission
May 2nd, 2025
SEC FORM D

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.The reader should not assume that the information is accurate and complete.

U.S. Securities and Exchange Commission
May 2nd, 2025
SEC FORM D/A

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.The reader should not assume that the information is accurate and complete.

Silverwood Partners
Feb 8th, 2024
Healthcare Private Placement and M&A Transactions Review Week Ending Feb 4, 2024 | Silverwood Partners

Strategy | Financing Transactions Private Placement / Financing Transactions Cellanome: The company raised $150 million of Series B venture funding from Premji Invest (US) and undisclosed investors on January 29, 2024, putting the company’s pre-money valuation at $375 million. The company is a developer of a unique multi-omics platform designed to measure biology at an unprecedented […]