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KBI Biopharma

CDMO delivering cell line development

Manager – Operational Excellence

Business OperationsConfirmed live in the last 24 hours
Full-timeBoulder, CO, USAIn-person

About the Job

Requirements

  • A proven track record of using Operational Excellence, Lean, or Six Sigma tools to improve processes, eliminate waste, and achieve sustainable business results.
  • Demonstrated ability to lead the design and implementation of streamlined Operational Excellence tools for problem solving, 5S, Kanban, visual controls, Kaizen, standard work, mistake-proofing, value stream mapping, line balancing, just-in-time manufacturing, business process management, Six Sigma, and strategy deployment.
  • Proficiency with modern training techniques, including e-learning, case studies, and the development of in-person and virtual learning simulations.
  • Strong Kaizen facilitation skills and substantial experience in rapid problem solving and value stream mapping.
  • Ability to interpret and analyze statistical data and financial reports, resolve technical difficulties, and interface with technical experts.
  • Strong visual communication skills and ability to present complex information clearly and concisely.
  • Strong written and verbal communication, listening, and influencing skills, including communication across all organizational levels.
  • Ability to manage multiple priorities and lead complex cross-functional projects and initiatives in matrixed global organizations.
  • Ability to develop and promote creative solutions, challenge existing ways of working, and influence significant change improvements.
  • Demonstrated collaboration, trust and respect, high standards, and learning and growth behaviors.
  • Strong business and financial acumen, including ability to identify and quantify financial benefits.
  • Strong project and change management skills.
  • Ability to motivate, influence, and coach others under direct or indirect management.
  • Experience driving change in good manufacturing practice and heavily regulated environments.
  • A B.S. or B.A. degree in a science or engineering field, or an equivalent combination of education and experience.
  • At least five years of experience in Operational Excellence.

Responsibilities

  • Support establishment of the site continuous improvement framework and strategic deployment plan to meet business objectives and build a culture of Operational Excellence.
  • Identify and prioritize site and functional improvement opportunities to increase customer value and eliminate waste using value stream mapping, Kaizen, and Hoshin Kanri strategy deployment.
  • Compile and manage a transformational Operational Excellence portfolio of projects across site functions and the full value stream to support functional and site business objectives.
  • Lead and execute critical cross-functional site continuous improvement projects and capture sustained benefits using the continuous improvement framework.
  • Provide mentorship, coaching, Kaizen support, tools, training, opportunity identification support, barrier removal, and benefit capture to site Operational Excellence and Kaizen leaders; develop Operational Excellence leaders to train others and lead cross-functional improvements.
  • Lead the site community of Operational Excellence leaders and align project outcomes, recognition, reporting, and messaging among department and functional leads.
  • Support identification, definition, collection, and clear reporting of key performance indicators across the business.
  • Design, develop, and deliver streamlined Operational Excellence tools and training using modern learning approaches to optimize learning, meet varied learner needs, and increase time to competency.
  • Maintain partnerships and collaborate with functional leaders to identify improvement opportunities and ensure sustained results.
  • Drive the business process management model within the continuous improvement framework to eliminate waste, promote simplification, and improve process flow.
  • Develop clear, concise Operational Excellence reports, presentations, digital communications, and visuals to convey key messages and metrics.
  • Participate in, coordinate, provide input to, and facilitate global process improvement initiatives.
  • Provide input to ensure business changes, key decisions, capital projects, and adjacent initiatives align with the overall Operational Excellence strategy.
  • Ensure Operational Excellence alignment with company cultural objectives.
  • Support introduction of new manufacturing technology, operations modeling, and risk management activities as requested.
  • Model, promote, recognize, and influence effective Operational Excellence behaviors and tool usage, and act as a change agent for cultural adoption of continuous improvement.
  • Leverage artificial intelligence and digital technologies to identify opportunities, solve complex problems, automate processes, and develop solutions that drive continuous improvement and operational excellence.

Desired Qualifications

  • Lean or Six Sigma Green Belt, Black Belt, or Master Black Belt certification.
  • Experience mentoring others through Lean Six Sigma certification.

About the Company

KBI Biopharma

CDMO delivering cell line development

KBI Biopharma is a CDMO that accelerates the development of biological medicines by providing rapid cell line generation and process development for preclinical programs. It uses established mammalian and microbial expression systems (such as CHO K1, CHO S, CHO DG44, HEK293, and DXB11 E. coli) to create production cell lines and develop integrated manufacturing processes. Compared with competitors, it wins on speed, end-to-end capability, and flexibility across multiple platforms to move projects quickly from discovery to preclinical milestones for a diverse client base. Its goal is to reduce risk, shorten development timelines, and expand global access to life-saving biologic therapies.

Company size
1,001-5,000
Company stage
Late Stage VC
Total funding
$109.5M
Headquarters
Durham, NC
Founded
1996

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