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Becoming

AI-guided closed-loop mammalian development systems

Machinist / Prototype Fabrication Engineer

Full-TimePosted on 10/22/2026
$90k - $140k+ Equity
Mid
San Francisco, CA, USA
In PersonOn-site in San Francisco.
Manufacturing & Production OperationsPrecision Machining & Toolmaking

About the job

Requirements
  • Have substantial hands-on machining experience.
  • Be highly capable with CNC milling and/or turning.
  • Be comfortable with manual mills and lathes.
  • Be able to independently take a component from drawing or computer-aided design through fabrication.
  • Understand geometric dimensioning and tolerancing, tolerancing, fits, surface finishes, and inspection.
  • Have strong intuition for manufacturability.
  • Be comfortable working across metals and engineering polymers.
  • Enjoy working directly with engineers in a fast-moving research and development environment.
  • Take pride in the quality of physical items built.
Responsibilities
  • Machine precision components for experimental hardware.
  • Operate CNC mills, lathes, and manual machining equipment.
  • Build custom fixtures, jigs, adapters, enclosures, and experimental components.
  • Work from computer-aided design, engineering drawings, sketches, and early-stage concepts.
  • Advise engineers on manufacturability, tolerances, materials, and fabrication approaches.
  • Rapidly modify components in response to experimental results.
  • Develop machining strategies for unusual geometries and low-volume parts.
  • Inspect components and verify critical dimensions.
  • Support assembly, troubleshooting, repair, and modification of experimental hardware.
  • Help build an internal rapid-prototyping capability.
Desired Qualifications
  • CAM programming.
  • Multi-axis machining.
  • Precision fabrication.
  • Scientific instrumentation.
  • Medical-device hardware.
  • Prototype development.
  • Metrology and inspection.
  • Welding or other fabrication techniques.
  • Experience working in an internal research and development machine shop.

About the company

Becoming.ai builds robotic systems with closed-loop metabolic control to sustain mammalian development outside the body, paired with AI models that learn how development unfolds under different interventions. Its core hardware delivers nutrients, removes waste, and controls gas exchange in real time, creating a controllable environment for long-running developmental data. The AI analyzes this data to predict developmental trajectories and identify interventions that shift outcomes, enabling virtual organism models. The company differentiates itself by combining hardware-enabled metabolic exchange with dynamical AI models to generate and study controlled developmental data over extended periods, rather than just analyzing static biological samples. Its goal is to enable long-term, predictable developmental studies that can inform regenerative medicine, drug discovery, and fundamental developmental biology.

Company Size

11-50

Company Stage

N/A

Total Funding

N/A

Headquarters

N/A

Founded

2023

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Simplify's Take

What believers are saying

  • February 2026 EF coverage and August 2026 job posts show active technical hiring.
  • Becoming is recruiting applied AI, robotics, and dynamical-systems talent, signaling platform expansion.
  • Its 2026 story fits pharma demand for longer-horizon developmental data and intervention testing.

What critics are saying

  • Development depends on unproven lab-grown placenta hardware; Core Memory said no literature precedent in March 2026.
  • Colossal and Nexaborn are entering artificial-womb territory, compressing Becoming’s technical lead.
  • Ethical and regulatory scrutiny around mammalian development outside bodies can trigger shutdowns within 12 months.

What makes Becoming unique

  • Becoming’s 2026 white paper pairs ex utero mammalian development with predictive AI models.
  • Its closed-loop robotic metabolic exchange regulates nutrients, waste, and gas exchange in real time.
  • EF reported Becoming grew a mouse embryo with a beating heart and lab-grown placenta.

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Benefits

  • Company Equity

Growth & Insights

6 month growth

-5%

1 year growth

-14%

2 year growth

-14%