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Xaira Therapeutics

AI-powered protein design for therapeutics

Senior Associate Scientist - High Throughput Protein Production

Translational Research & Bench BiologyConfirmed live in the last 24 hours
Full-timeSouth San Francisco, CA, USAIn-person

About the Job

Requirements

  • A BS or MS in Biochemistry, Molecular Biology, or a related field, with 5 or more years of experience in protein expression and purification.
  • A strong operational understanding of automation, work cells, and protein science principles and methodologies.
  • Experience with high-throughput mammalian expression systems.
  • Experience with protein purification techniques, including affinity chromatography and polishing steps.
  • The ability to design and optimize protein purification protocols.
  • Strong analytical and problem-solving skills.
  • Strong communication and interpersonal skills.
  • The ability to work independently and as part of a team.

Responsibilities

  • Operate and optimize high-throughput protein production workflows for antibody modalities.
  • Implement and integrate automation platforms to ensure seamless workflow.
  • Develop and validate methods for automated protein purification.
  • Troubleshoot automation issues and improve efficiency and yield.
  • Stay current with advancements in automation and protein production.
  • Collaborate across disciplines to optimize workflows.
  • Design a data management system to track protein production data.
  • Document automated protein production processes.
  • Analyze data and identify areas for improvement.
  • Prepare reports and presentations.

Desired Qualifications

  • Experience with automated liquid handling systems and robotic platforms.
  • Programming skills such as Python or R for scripting automation workflows.

About the Company

Xaira Therapeutics

AI-powered protein design for therapeutics

Xaira Therapeutics uses artificial intelligence to transform drug discovery and development. It builds a pipeline of protein- and antibody-based therapeutics by combining generative AI models from the IPD lab (notably RFdiffusion and RFantibody) with large, multidimensional biological data. The company designs novel proteins and antibodies from scratch to target difficult, previously undruggable biology, then validates and evolves these molecules through iterative data generation that improves its biological foundation models. Unlike many entrants that offer research services, Xaira aims to own and advance its own therapeutic pipeline across multiple modalities, rather than solely providing platforms. The goal is to deliver effective new medicines faster and with a lower chance of failure by integrating AI-driven design, expansive data, and expert leadership.

Company size
201-500
Company stage
Late Stage VC
Total funding
$1B
Headquarters
South San Francisco, CA
Founded
2023

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