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Frontier Medicines

Develops precision oncology drugs using chemoproteomics

IT Manager/Senior IT Manager

System AdministrationPosted on Nov 12
ContractBoston, MA, USA$118k - $185k /yr

About the Job

Requirements

  • At least 5 years of hands-on experience running enterprise IT infrastructure.
  • Expert knowledge of VMware vSphere, enterprise storage, and backup and recovery.
  • Strong understanding of computer architecture, networking, virtualization, storage, and operating systems in a mixed macOS, Windows, and Linux environment, with extensive experience administering and troubleshooting Windows and Linux servers.
  • Experience managing Meraki and Palo Alto networks, including firewall rules and site-to-site virtual private networks.
  • Experience administering Okta, Intune, and Jamf.
  • Experience managing and securing AWS accounts and services.
  • Ability to troubleshoot complex issues across systems and explain the fix clearly in writing.
  • Ability to work independently on a small team, with sound judgment and attention to detail.
  • Legally authorized to work in the United States.

Responsibilities

  • Administer VMware vSphere hosts and virtual machines, patch servers and applications, and monitor capacity and performance.
  • Manage the on-site data center, including server hardware, uptime of the hosting environment, physical access, and the relationship with facility management.
  • Administer TrueNAS and Synology storage systems, and manage Rubrik backups, restore testing, and disaster recovery.
  • Manage Meraki LAN and wireless networks, Palo Alto firewall rules, DNS, remote access, and site-to-site VPNs, and troubleshoot connectivity issues.
  • Administer Okta, including single sign-on, multifactor authentication, access policies, application integrations, and user lifecycle automation.
  • Manage AWS accounts and services by configuring resources, enforcing access controls, and monitoring security posture.
  • Set Intune and Jamf policies, including configuration profiles, compliance rules, security baselines, operating system and application updates, and application deployment.
  • Detect and respond to security threats, protect endpoints, email, and the network, and manage vulnerabilities and third-party risk.
  • Lead the assigned areas from day-to-day administration through planning and vendor relationships, working closely with the rest of the IT team.

Desired Qualifications

  • Experience in a life sciences or biotech environment is strongly preferred.
  • Experience working in a regulated environment, with awareness of compliance standards such as HIPAA, GDPR, and Sarbanes-Oxley, and IT control frameworks such as NIST and ISO, is preferred.
  • Certifications in VMware, AWS, Okta, or Palo Alto are a plus.

About the Company

Frontier Medicines

Develops precision oncology drugs using chemoproteomics

Frontier Medicines develops precision medicines for genetically defined patient populations, mainly in oncology and other hard-to-treat diseases. It uses chemoproteomics, covalent drug discovery, and machine learning to identify small molecules against difficult targets and advances candidates through clinical development toward commercialization. Its lead program FMC-376 targets KRAS G12C in both active and inactive states, and it has built the AutoTAC platform for targeted protein degradation to expand potential drug modalities. The company differentiates itself by combining genetics-driven target selection with advanced proteomics and chemistry within a platform approach that supports partnerships and licensing with larger pharma to bring therapies to patients.

Company size
51-200
Company stage
Series C
Total funding
$255.5M
Headquarters
South San Francisco, CA
Founded
2018

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