Director, US Real-World Evidence and Health Outcomes: Non-Small Cell Lung Cancer

Director, US Real-World Evidence and Health Outcomes – Non Small Cell Lung Cancer (NSCLC)

Office-based: Philadelphia, PA or Durham, NC; travel as required (typically up to ~20%). Reports to: Sr. Director and Head, US RWE/HO Oncology

Role Summary:

The role of Director, US Real-World Evidence & Health Outcomes Research Scientist Hematology-Oncology ensures that each medicine GSK brings to market is supported by scientifically credible, high quality evidence that drives competitiveness and strong evidence-based product positioning, value propositions, and value-based pricing.  The role is accountable for developing and delivering components of the US data generation plan (including RWE and economic value evidence), ensuring strategic alignment across key internal stakeholders (US Medical, Commercial/Market Access, Global RWE & HO, Global Medical Affairs, R&D Epidemiology and Clinical Development), and driving high-quality deliverables that inform internal decision-making during product development, pre-launch readiness, and lifecycle planning. This role promises a fast-paced environment supporting a new-to-market product in a dynamic hematology space. 

Key Responsibilities:

• Evidence strategy and planning: Implementation of RWE/HO research by developing evidence generation plan and designing multiple RWE/HO studies, aligned to US medical, payer, and access needs; translate strategy into actionable workplans, timelines, and resourcing proposals. Translate needs for evidence into study concepts in alignment with strategic objectives and vision for the asset, e.g. development of study protocols and proposing innovative and cost-effective ways of developing and executing studies
• Study leadership (RWE/HEOR): Own day-to-day leadership for assigned real-world evidence and health outcomes studies (e.g., real-world evidence studies, cost-effectiveness/budget impact analyses, burden of illness, treatment patterns, patient-focused outcomes) including design and execution in partnership with internal functions and external vendors.

o   Ensure key stakeholders, including TA aligned business leaders, are regularly updated on plans through periodic reporting.

o   Develop excellent working relationships with external thought leaders to ensure appropriate methods and research agendas are applied, in

accordance with GSK policies.

• Cross-functional stakeholder management: Build strong working relationships with internal stakeholder groups across medical, market access, R&D and commercial to ensure strategic alignment and optimal cross-functional collaboration and communication.  Lead cross-functional stakeholder meetings to align on evidence generation gaps and priorities.
• Scientific communication and quality: Draft/review project specifications, protocols, statistical analysis plans, study reports, abstracts, posters, and manuscripts; ensure adherence to SOPs and high scientific/operational quality.
• Internal decision support: Provide RWE & HO input to internal decision-making during development and commercialization planning (e.g., trial design considerations, data gap assessments, value messages, evidence prioritization and sequencing).
• External insight generation: Maintain strong alignment with Field Based Payer Medical Teams and other field stakeholders to obtain customer insights; incorporate insights into evidence plans and value communication needs.
• Vendor and budget management: Manage vendors and contractors for assigned studies, including scope, timelines, budget tracking, and change control; escalate risks/issues proactively.
• Governance, compliance, and capability building: Complete required training, adhere to company/department SOPs, and contribute to continuous improvement of processes that enable efficient planning, execution, and dissemination of RWE & HO deliverables.

Basic Qualifications:

• Master’s degree or PhD in health economics and outcomes research, epidemiology, public health, biostatistics, or related discipline.
• 5+ years’ experience within the pharmaceutical industry or academia related research within US Oncology experience.
• Designing a publication plan and having a presence of RWE/HO research studies at major clinical congresses
• Experience managing multiple projects simultaneously (Basic Qualification)
• Experience in RWE and economic evaluation study designs/methods evidenced by publications and/or contributing to study concept sheets and protocols (including clear research questions, endpoints, data source selection, and bias/confounding mitigation), reviewing/authoring key sections of statistical analysis plans and study reports, and ensuring publication/disclosure readiness in accordance with internal SOPs and external requirements.

Preferred Qualifications:

• Demonstrated success developing and executing health outcomes research plans and delivering high-quality data generation outputs.
• Oncology (NSCLC) experience (US or global), including familiarity with evolving standards of care, evidence requirements, and stakeholder needs across disease areas.
• Masters + ~4–6 years or PhD with 2–4+ years of experience within the pharmaceutical industry and/or managed care, hospital, academic, or healthcare consulting environment, including experience collaborating with field-facing teams (e.g., Field Based Payer Medical, Field Medical) and/or Market Access partners.
• Experience managing real-world data sources and vendors (e.g., claims, EHR, registries) and translating findings into actionable insights and value messages.
• Demonstrated ability to influence without authority in a matrix environment, evidenced by aligning cross-functional stakeholders on objectives/trade-offs, documenting decisions, and driving actions to closure.
• Strong communication and presentation skills, demonstrated by developing and presenting clear, decision-oriented materials (e.g., evidence strategy slides, executive readouts) and summarizing outcomes/next steps for senior audiences.
• Proven ability to prioritize, pivot, and manage multiple projects simultaneously in a matrix environment.
• Strategic execution experience, demonstrated by translating evidence strategy into workplans (milestones, timelines, resourcing) and delivering outputs across 1–2 concurrent asset workstreams.
• Demonstrated project and vendor management experience, including defining scope and success criteria, tracking budgets/timelines, proactively identifying risks/issues, and implementing mitigation plans through change control.
• Experience contributing to congress strategy and publication planning (abstracts, posters, manuscripts).

#LI-GSK

Skills

Cross-Functional Leadership, Digital Fluency, Enterprise Thinking, Evidence Based Decision Making, Flexible Mindset, High Impact Communication, Launch Excellence, Patient Journey

Please visit  GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

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