Pioneering Medicines: Principal Scientist
Toxicology
Posted on 1/26/2024
INACTIVE
Flagship Pioneering

501-1,000 employees

Originates biotech ventures for health and sustainability
Company Overview
Flagship Pioneering stands out as a leader in the biotechnology industry, having originated and nurtured over 100 scientific ventures, including high-profile companies like Moderna and Indigo Agriculture. The company's culture is rooted in developing transformative products for human health and sustainability, as evidenced by their creation of platform companies like Generate Biomedicines and Tessera Therapeutics. Their competitive edge lies in their ability to explore new frontiers in genetics, as demonstrated by their recent unveiling of Quotient Therapeutics, a venture aimed at creating transformative medicines.
Venture Capital

Company Stage

N/A

Total Funding

$6.4B

Founded

2000

Headquarters

Cambridge, Massachusetts

Growth & Insights
Headcount

6 month growth

6%

1 year growth

15%

2 year growth

56%
Locations
Cambridge, MA, USA
Experience Level
Entry
Junior
Mid
Senior
Expert
CategoriesNew
Biology & Biotech
Requirements
  • BS, MS or PhD in toxicology, pharmacology, physiology, biology, immunology or related sciences
  • Experience in preclinical/nonclinical safety, pharmacology, and/or biology experience in the pharmaceutical/biotechnology industry
  • 10+ years required for Bachelors degree
  • 8+ years required for Masters degree
  • 5+ years required with PhD
  • Study design, planning, execution, and monitoring experience for external non-GLP and GLP toxicology studies (in vitro and in vivo) studies
  • Safety assessment experience (on- and off-target)
Responsibilities
  • Serve as the project toxicologist for projects at various stages of discovery and development
  • Conduct safety assessments (on- and off-target)
  • Contribute to study design, planning, execution, and monitoring of external non-GLP and GLP toxicology studies (in vitro and in vivo) studies
  • Contribute to the development an in silico and in vitro screening strategy to understand potential toxicological liabilities for new modalities
  • Manage contracts and coordinate activities with CROs for non-GLP and GLP toxicology studies
  • Support the preparation of study reports with external labs
  • Lead the preparation of regulatory documents, including INDs, investigator’s brochures, and NDAs/BLAs
  • Work closely with other functional areas such as biology, in vitro and in vivo pharmacology, DMPK, modeling and simulations, CMC and Clinical as well as internal and external collaborators