Senior Manager - Program Management

The Role:

Joining Moderna means advancing mRNA science to transform medicine. Work with exceptional global teams on a broad pipeline and build a career that makes a real difference for patients.

Moderna is strengthening its presence in Cambridge, Massachusetts, home to our global headquarters and a center of mRNA innovation. Working closely with leading universities and research institutions, our Cambridge team advances groundbreaking science that shapes the future of medicine. We welcome talent driven by innovation and committed to improving global health.

As Senior Manager, Program Management within Portfolio Development, you will be an individual contributor based at Binney, partnering with Lead Program Managers, Program Leaders, and cross-functional leaders to advance Moderna’s medicines and vaccines.

You will serve as a key thought partner and integrator, aligning program strategy, development plans, evidence generation, regulatory strategy, launch readiness, and execution priorities across the asset lifecycle.
This role calls for strong motivation, demonstrated experience working across complex cross-functional teams, strategic and operational leadership capabilities, and the ability to manage multiple programs or priorities in parallel.

Here's What You'll Do:

• Collaborate with Program Leaders, Lead Program Managers, and cross-functional leaders to drive integrated program strategy and execution across assigned programs that may span multiple products, indications, development stages, and therapeutic areas, including infectious disease, rare disease, oncology, and immunology. Depending on program stage and assignment, your responsibilities may extend from early development and pivotal readiness through filing, approval, launch preparation, and post-approval lifecycle planning and management.
• Lead the development and maintenance of integrated program plans that connect Research, CMC, Development, Medical Affairs, Commercial, and other relevant enabling functions. Bring together key activities, dependencies, timelines, milestones, critical paths, and decision points to support coordinated decision-making, integrated planning, and successful program progression.
• Drive cross-functional alignment by proactively identifying and managing risks, issues, and interdependencies. Coordinate mitigation, escalation, and resolution so teams understand how decisions and changes affect program priorities, development plans, and execution.
• Lead or support preparation for key stage-gate, regulatory, filing, approval, launch-readiness, and governance decisions, based on program stage and assignment. Ensure program materials clearly communicate progress, dependencies, risks, and decisions requiring leadership input.
• Facilitate effective program team meetings and working sessions, ensuring clear decisions, ownership, accountability, and follow-through. Translate cross-functional discussions into coordinated actions and ensure execution against critical program milestones.
• Integrate Medical Affairs and Commercial priorities into program planning, including evidence generation, medical and commercial readiness, launch planning, and lifecycle activities, as appropriate to program stage. Maintain alignment between these priorities, development plans, regulatory strategy, and overall program objectives.
• Develop scenario analyses, recommendations, and program materials to support strategic and operational decision-making. Help teams evaluate options, understand trade-offs, and determine how alternative approaches affect timelines, dependencies, and execution priorities.
• Monitor program progress against key milestones, budgets, and objectives. Provide clear visibility into program performance and areas requiring leadership attention, supporting timely decisions and appropriate course corrections.
• Lead assigned programs, indications, workstreams, or cross-functional initiatives with an appropriate level of independence. Balance multiple programs or priorities in parallel while contributing to broader Program Management capabilities and best practices.
• Explore opportunities to use generative AI tools to support information synthesis, integrated planning, and program communications, where appropriate, with human review and safeguards for confidential information.

The key Moderna Mindsets you’ll need to succeed in the role:

• “We act with dynamic range, driving strategy and execution at the same time at every step.” You will connect asset-level strategy with integrated plans, governance decisions, and milestone delivery, moving between strategic thinking and operational detail as programs progress.
• “We remove viscosity to encourage collective action.” You will bring functions together, clarify interdependencies, and establish clear ownership and follow-through so complex program teams can make coordinated decisions and move forward.

Here’s What You’ll Need:

• BS degree in a scientific field with a minimum of 6 years of experience or MS degree in a scientific field at least 4 years of experience in a biotechnology or pharmaceutical setting.
• Proven track record of successful project management experience in drug development across multiple phases (pre-clinical and clinical Phase 1-3).
• Prior experience managing or working within cross-functional project teams with timeline management and budgetary responsibility.
• Strong knowledge of project management tools and software (e.g., Smartsheet, MS Project, and timeline visualization software).
• Must be adept at working in a fluid environment and foster a strong collaborative spirit internally and externally.
• Strong personal skills to influence without authority, motivate others and manage conflict.
• Strong written and oral communication skills as well as demonstrated organizational aptitude.

Here’s What You’ll Bring to the Table:

• Project/program management training.
• Ph.D. or PharmD and 2+ years of experience in a biotechnology or pharmaceutical setting.
• Experience leading or coordinating regulatory filings.
• Laboratory experience in an academic or biotechnology setting.

Our Working Model 

As we build our company, we have always believed an in-person culture is critical to our success.

Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact.

Moderna is a smoke-free, alcohol-free, and drug-free work environment.

Pay & Benefits

At Moderna, we believe that when you feel your best, you can do your best work. That’s why our benefits and well-being resources are designed to support you—at work, at home, and everywhere in between.

• Competitive healthcare, plus voluntary benefit programs to support your unique needs
• A holistic approach to well-being, with access to fitness, mindfulness, and mental health support
• Family planning benefits, including fertility, adoption, and surrogacy support
• Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown
• Savings and investments to help you plan for the future
• Location-specific perks and extras

The salary range for this role is $130,800.00 - $209,400.00. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An individual’s position within the salary range will be based on several factors including, but not limited to, specific competencies, relevant education, qualifications, certifications, experience, skills, performance, and business or organizational needs.

The successful candidate may be eligible for an annual discretionary bonus, other incentive compensation, or equity award, subject to company plan eligibility criteria and individual performance.

About Moderna

Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.  

By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities. 

We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. 

If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities. 

Equal Opportunities

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law.  Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!

Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements. 

Accommodations

We’re focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best. 

Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at [email protected]. 

Export Control Notice
This position may involve access to technology or data that is subject to U.S. export control laws, including the Export Administration Regulations (EAR). As such, employment is contingent upon the applicant’s ability to access export-controlled information in accordance with U.S. law. Due to the nature of the work and regulatory requirements, only individuals who qualify as U.S. persons (citizens, permanent residents, asylees, or refugees) are eligible for this position. For this role Moderna is unable to sponsor non-U.S. persons to apply for an export control license.


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