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Wave Life Sciences USA

Clinical-stage biotech developing stereopure oligonucleotides

Oligo Chemistry and Biochemistry Co-op

Bioprocess & BiomanufacturingConfirmed live in the last 24 hours
Internship · Spring 2027Cambridge, MA, USAIn-person

About the Job

Requirements

  • Be a co-op student.
  • Have strong organizational skills and attention to detail.
  • Organic chemistry or biochemistry laboratory experience is preferred.
  • Follow laboratory safety protocols, including use of personal protective equipment.

Responsibilities

  • Assist with upstream and downstream biochemical, bioanalytical, and biological analysis of oligonucleotides.
  • Prepare reagents and buffers for biochemical, bioanalytical, and biological experiments by measuring organic compounds and solution volumes.
  • Prepare buffer solutions of specified molarity for liquid chromatography analysis of oligonucleotides.
  • Assist in operating the liquid chromatography-mass spectrometry system and learn to work on it.
  • Assist with physicochemical experiments on oligonucleotides, including thermal denaturing experiments.
  • Maintain a detailed report of experimental procedures and findings in electronic lab notebooks.
  • Use a pH meter and NanoDrop to record data.
  • Present experimental data in team meetings.

Desired Qualifications

  • Use of Microsoft Excel is preferred.

About the Company

Wave Life Sciences USA

Clinical-stage biotech developing stereopure oligonucleotides

Wave Life Sciences develops stereopure nucleic acid therapies for genetically defined diseases. Its PRISM platform designs stereopure oligonucleotides that enable RNA interference, antisense silencing, splicing modulation, and RNA editing, including AIMers that recruit ADAR enzymes to edit RNA without changing the DNA. The company funds R&D mainly through partnerships and licensing (notably with GSK) and has programs in conditions like Alpha-1 antitrypsin deficiency, Duchenne muscular dystrophy, Huntington’s disease, and obesity. Its goal is to bring approved RNA medicines to patients by advancing a diversified pipeline and sustaining long-term collaborations that fund development.

Company size
201-500
Company stage
IPO
Headquarters
Cambridge, MA
Founded
2012

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