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Treeline Biosciences

Biotech firm discovering cancer therapies.

Principal Information Systems Engineer

System AdministrationConfirmed live in the last 24 hours
Full-timeWatertown, MA, USA$180.3k - $196.8k /yrIn-person

About the Job

Requirements

  • A bachelor's degree in Information Technology or Computer Science, or equivalent work experience.
  • 8-10+ years of experience in systems administration, endpoint management, identity management, or IT operations.
  • Broad overall IT experience, including Windows, Mac, databases, storage, security, networking, and public clouds.
  • Strong hands-on experience with Microsoft 365 administration, Microsoft Intune, ManageEngine Endpoint Central, Microsoft Entra ID including Conditional Access Policies, Okta, endpoint security and device management, Multi-Factor Authentication, and PowerShell at a basic to intermediate level.
  • Strong troubleshooting, problem-solving, and analytical skills.
  • A track record of taking ownership in issue resolution.
  • Familiarity with ticketing systems and ITSM processes.
  • Experience working collaboratively with coworkers and vendors, both locally and remotely, while also being effective working independently.
  • Ability to explain technical issues clearly to non-technical users.
  • Ability to prioritize tasks and manage multiple issues simultaneously.

Responsibilities

  • Serve as the primary technical escalation point for the IT organization, including providing hands-on support to end users as needed.
  • Provide hands-on leadership for complex technical initiatives.
  • Serve as a secondary technical decision-maker for IT Operations and provide recommendations to the Director on tooling, standards, and vendor issues.
  • Administer, support, and optimize cloud-based enterprise technologies, including endpoint, identity, and security management solutions.
  • Manage modern workplace technologies and troubleshoot complex technical issues.
  • Administer and maintain Microsoft 365, Microsoft Intune, and Microsoft Entra ID environments, including Conditional Access Policies and endpoint security configurations.
  • Manage identity and access solutions, including Okta and Multi-Factor Authentication, to safeguard Treeline systems and data.
  • Develop and maintain PowerShell scripts to automate routine administrative tasks and improve operational efficiency.
  • Partner with in-house engineers and Managed Service Providers to support employees across multiple departments and countries.
  • Maintain accurate documentation, ticket updates, and knowledge base articles in accordance with established ITSM processes.
  • Collaborate with local and remote coworkers and vendors to design, implement, and continuously improve IT solutions.

Desired Qualifications

  • Previous experience working in a biotech startup or biopharmaceutical company.
  • Related certifications.

About the Company

Treeline Biosciences

Biotech firm discovering cancer therapies.

Treeline Biosciences develops proprietary therapies for cancer and other serious diseases by conducting in-depth R&D across biology, chemistry, protein sciences, and computational science. Its product work involves discovering and optimizing drug candidates, then licensing these therapies to larger pharmaceutical companies or selling them to healthcare providers, with support from CRO collaborations to speed development. The company differentiates itself through a balanced mix of in-house research and external partnerships, a robust IP strategy, and a team that blends experienced biotech veterans with new talent, all backed by funding from KKR to scale operations. Its goal is to build a sustainable, long-term pipeline of treatments that can reach patients while expanding capabilities and partnerships in the biotech ecosystem.

Company size
51-200
Company stage
Series A
Total funding
$1.1B
Headquarters
Stamford, CT
Founded
2021

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