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Moderna

Develops mRNA-based medicines for health

Global Medical Affairs Lead - Oncology

Biology & BiotechConfirmed live in the last 24 hours
Full-time

About the Job

Requirements

  • MD or non-US equivalent, PharmD, or PhD with extensive oncology medical affairs leadership experience.
  • Minimum of 15 years of experience in Medical Affairs, with a strong track record in global roles.
  • Demonstrated leadership of global launch planning and execution in oncology or immuno-oncology settings.
  • Deep expertise in the oncology therapeutic area.
  • Experience in regulatory affairs, scientific communication, and external stakeholder engagement.
  • Global and/or local launch experience.

Responsibilities

  • Own and lead the global medical strategy across the oncology portfolio, integrating work from early development through lifecycle management.
  • Serve as final medical accountability holder for assigned oncology programs, including delivery of the integrated medical plan.
  • Lead medical participation in governance bodies and cross-functional decision-making forums, aligning development, regulatory, and commercial functions.
  • Lead the Development Integrated Evidence Team to build comprehensive data packages for regulators, payers, and other stakeholders.
  • Act as global medical lead in interactions with health authorities and payers, providing strategic input and medical representation.
  • Direct a cross-functional global medical matrix team covering Scientific Communications, Field Medical, and Patient Advocacy, ensuring timely execution of deliverables.
  • Lead global launch readiness for oncology assets, including medical training, evidence generation, scientific engagement, and narrative development.
  • Build partnerships with global, regional, and national thought leaders to shape best practices and influence health policy.
  • Develop and execute publication strategies, medical education initiatives, and real-world evidence programs to strengthen knowledge exchange.
  • Manage medical affairs budgets and resource planning for assigned programs, aligning with broader franchise objectives.
  • Partner with the VP, Oncology, and cross-functional stakeholders to shape the long-term medical direction and investment strategy for the franchise.
  • Take ownership of medical strategy for oncology assets and drive execution and accountability across cross-functional teams.
  • Leverage AI-powered data tools and Moderna’s digitally integrated ecosystem to support evidence generation, decision-making, and medical excellence.

Desired Qualifications

  • Melanoma and immunotherapy experience.
  • A strong track record of key opinion leader engagement, scientific communication, and external representation.
  • Experience navigating strategic external collaborations and cross-company governance.
  • Expertise in cross-functional team leadership, including pharmacovigilance, biostatistics, clinical operations, and regulatory affairs.
  • A strategic and operational mindset with project leadership capabilities.
  • Ability to manage cross-functional deliverables and own timelines and outputs at a program level.
  • Ability to translate complex science into clear, impactful messaging.
  • Ability to balance strategic leadership with hands-on execution in a fast-paced environment.

About the Company

Moderna

Develops mRNA-based medicines for health

Moderna develops medicines built on messenger RNA (mRNA). Its products use mRNA delivered into cells to instruct them to produce specific proteins that can prevent or treat disease, with vaccines being a primary example. In practice, a dose delivers engineered mRNA into the body, cells translate it into a target protein, and the immune system responds or the protein modulates biology to combat disease. Moderna differentiates itself through its focus on building a whole mRNA medicines platform and in-house capabilities for designing, manufacturing, and scaling mRNA therapies, including rapid development and large-scale production. Its goal is to create a new category of medicines based on mRNA that can improve how diseases are discovered, developed, and treated, ultimately improving patient outcomes.

Company size
5,001-10,000
Company stage
IPO
Headquarters
Cambridge, MA
Founded
2010

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