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Arrowhead Pharmaceuticals

Develops RNAi-based gene-silencing therapies

Associate Manufacturing Scientist 1

Bioprocess & BiomanufacturingConfirmed live in the last 24 hours
Full-timeVerona, WI, USA

About the Job

Requirements

  • A Bachelor of Science or Master of Science degree in chemistry, biochemistry, engineering, or a related scientific field.
  • Entry-level to three years of experience in a similar position.
  • Good verbal and written communication skills.
  • Ability to work in a team environment.
  • Ability to pay attention to detail.

Responsibilities

  • Follow batch records, standard operating procedures, and work instructions in detail.
  • Document all operations in batch records and notebooks.
  • Comply with good manufacturing practice protocols.
  • Assist other chemists within the CMC group during synthesis and chromatography of oligonucleotides, including reagent solution preparation, column packing, mobile phase preparation, and fraction collection.
  • Operate tangential flow filtration equipment to desalt purified RNA solutions.
  • Operate a lyophilizer and package solid drug substance.
  • Execute processes as part of a team to meet production timelines and produce quality product.
  • Maintain a clean workspace.
  • Maintain safety by wearing required personal protective equipment.

Desired Qualifications

  • Experience working in a good manufacturing practice setting with controlled documentation.

About the Company

Arrowhead Pharmaceuticals

Develops RNAi-based gene-silencing therapies

Arrowhead Pharmaceuticals develops medicines using RNA interference (RNAi) to silence disease-causing genes. The company’s approach uses a library of RNA chemistries and delivery methods to trigger RNAi, enabling rapid and durable reduction of target gene expression in cells. This gene-silencing strategy aims to treat severe genetic diseases such as cystic fibrosis and hepatitis B by lowering disease-related proteins. Arrowhead’s products are advanced through discovery and development partnerships, licensing deals, and potential commercialization of approved therapies. The company differentiates itself through a broad RNAi platform, proprietary delivery tech, and collaborations with larger pharma firms to advance its pipeline. Its goal is to provide new treatment options for conditions with limited or no effective therapies by translating gene silencing into medicines that can halt or reverse disease progression.

Company size
501-1,000
Company stage
IPO
Headquarters
Pasadena, CA
Founded
2004

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