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Midstream Health

AI-powered platform for hospital cost optimization

Head of Finance

Full-Time
No salary listed
Expert
San Francisco, CA, USA
In Person
Finance & BankingCorporate Finance & FP&A

About the job

Requirements
  • A strong foundation in finance and an understanding of how businesses and investments are evaluated.
  • Several years of experience in private equity, growth equity, venture capital, investment banking, strategic finance, or another highly analytical environment.
  • Ability to move between detailed financial analysis and high-level company strategy.
  • Ability to reason from first principles and develop and defend a point of view with incomplete information.
  • Ability to communicate clearly with senior stakeholders and build trust over time.
  • Willingness to challenge assumptions, including those of senior leaders, and take ownership of outcomes.
Responsibilities
  • Work directly with the CEO on consequential company decisions by turning ambiguous questions into clear choices, developing an independent point of view, and moving from recommendation to decision and outcome.
  • Build and maintain the forward-looking financial and operating view used to run the company across growth, revenue, headcount, expenses, burn, runway, and capital needs; connect financial results to business activity, surface key assumptions and risks, and explain how major decisions affect the company's trajectory.
  • Prepare for and increasingly manage investor and Board interactions; develop materials and communications, anticipate stakeholder questions, and present company performance, strategy, and long-term opportunity coherently.
  • Help determine when and why the company should raise additional capital and what it should accomplish with that capital; connect operating choices to runway and future financing needs, shape fundraising strategy and projections, and maintain fundraising readiness.
  • Take responsibility for high-impact cross-functional problems, build context quickly, work with Product, Engineering, Commercial, Operations, and other teams, challenge assumptions, and follow the work through execution and outcomes.

About the company

Midstream Health builds an AI-powered financial action platform for health systems to cut costs beyond traditional revenue cycle management. It ingests and unifies financial, operational, and contract data into a single trusted source of truth, then uses domain-trained AI agents to identify and prioritize cost-saving actions such as recovering rebates, correcting invoices, preventing overpayments, and spotting payer underpayments, turning insights into real-time tasks. The platform is designed for fast deployment and promises a return on effort within four months. Midstream uses a shared-savings model, taking a portion of the savings it creates for large health systems like Mount Sinai, CommonSpirit Health, and Houston Methodist, with solutions for supply chain, managed care, and pharmacy.

Company Size

11-50

Company Stage

N/A

Total Funding

N/A

Headquarters

San Francisco, California

Founded

2023

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Simplify's Take

What believers are saying

  • CommonSpirit partnered in February 2026, then expanded Midstream into enterprise financial operations.
  • Houston Methodist expanded deployment in April 2026, starting with supply chain and broadening quickly.
  • Leadership additions in April 2026 signal hiring momentum and commercialization across live customers.

What critics are saying

  • Seed-only funding limits endurance against Oracle, Workday, and Epic entering health system finance.
  • Shared-savings pricing depends on provable savings; weak deployments kill renewals within twelve months.
  • Three flagship health systems create concentration risk; one failed rollout damages credibility across the coalition.

What makes Midstream Health unique

  • Midstream unifies fragmented hospital finance, contract, and spend data into validated action workflows.
  • Contract-aware AI agents target rebates, underpayments, and supply chain waste, not dashboards.
  • CommonSpirit, Mount Sinai, and Houston Methodist validate enterprise adoption across $80B net patient revenue.

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Benefits

  • Hybrid Work Options

Growth & Insights

Headcount

6 month growth

-3%

1 year growth

-3%

2 year growth

-3%