Alnylam Pharmaceuticals

Develops RNAi-based therapies for genetic diseases

Director – Global Market Access

Product MarketingConfirmed live in the last 24 hours

Full-timeCambridge, MA, USA

About the Job

Requirements

A bachelor's degree is required.
Ten or more years of commercial market access experience, including five or more years in rare disease.
Substantial experience in the United States, Europe, and emerging markets with market access strategies, launch pricing, contracting, reimbursement, and distribution concepts for specialty products.
Ability to develop solutions to unstructured strategy problems that link logically to revenue- and profit-specific business cases, including loss-of-exclusivity, launch, pricing, and clinical development strategies.
Ability to lead a high-performing cross-functional team and perform hands-on work despite conflicting priorities.
Strong written and verbal communication skills.
Experience presenting and communicating to C-suite leaders with clarity and business focus.
Strong business and scientific acumen and learning agility.
Ability to influence and build strong relationships in a matrix environment.
Ability to define, track, and analyze key access performance measures and make data-driven decisions.
Ability to prioritize, pivot, and manage multiple projects simultaneously.

Responsibilities

Lead global pricing and market access strategy for the Rare Disease portfolio and selected pipeline assets, bringing learnings across the team and representing the franchise on program development, market access, and brand leadership teams.
Analyze business cases and support decision-making for pricing requests for the Partner & Emerging Markets business unit in collaboration with Commercial Directors and external partners.
Manage the Global Pricing System, including quarterly price updates and portfolio reporting, improve the price approval process, and lead change management to prepare the system for enterprise needs.
Develop strategic access plans for in-line brands, new assets, and pipeline products in collaboration with global and regional cross-functional teams, covering access landscape development, payer segmentation and strategy, organized customer contracting and channel strategy, pricing, distribution, and value proposition development.
Communicate access-specific strategies to internal business partners for incorporation into brand planning.
Develop market access strategy from a commercial viewpoint with input from cross-functional teams.
Champion priority access initiatives with meaningful business impact to commercial leadership.
Collaborate with Global and Regional Market Access Strategy counterparts to share learnings across business units and drive franchise success.
Serve as the primary contact for pricing strategy discussions and guidance for the Partner & Emerging Markets business unit.
Build internal working partnerships with Regional Market Access, the Value & Evidence Strategy Team, Pricing, Advocacy/Policy, and Legal to drive critical decisions and ensure execution.
Lead development of the payer value story, supported by credible clinical, health economics, and patient-reported outcomes messages to justify brand value; work with the Value & Evidence Strategy team to guide evidence generation supporting payer value-story development.
Use understanding of the competitive landscape to anticipate competitor moves and develop market access strategies and tactics.
Provide input into above-brand access initiatives and incorporate learnings into branded access strategy.

Desired Qualifications

An MBA, Master of Public Health, Doctor of Pharmacy, or degree in Health Economics/Outcomes Research is preferred.

Overview:

Reporting to the VP, Global Market Access, the candidate will act as the overall lead for global pricing & market access strategy for Alnylam’s Rare Disease portfolio, as well as for selected pipeline assets, bringing key learnings across the team and representing the franchise as part of the program development, market access and brand leadership teams to ensure consistency of approach in securing access for current and future products.

In addition, the candidate will be directly responsible for analyzing business cases and support decision making for all pricing requests for Alnylam’s Partner & Emerging Markets (P&EM), collaborating directly with Commercial Directors and external partners.

Lastly, the candidate will be responsible for managing the Global Pricing System (GPS) including quarterly price updates and reporting across the portfolio, creating efficiency in price approval process and lead change management to make GPS future-ready for the enterprise.

Key Responsibilities:

In collaboration with cross-functional teams at global and regional level, lead the development of strategic access plans for all in-line brands, new assets, pipeline products inclusive of access landscape development, payer segmentation, payer strategy, organized customer contracting and channel strategy, pricing, distribution, and value proposition development.
Communicate access-specific strategies to internal business partners for incorporation into brand planning.
Develop market access strategy from commercial view point with input from cross-functional teams.
Help champion priority access initiatives with meaningful impact to the business to commercial leadership.
Collaborate with Global and Regional Market Access Strategy counterparts to share learnings across business units that will drive franchise success.
Serve as single-point-of-contact for all pricing strategy related discussions and guidance for P&EM business unit.
Develop internal working partnerships with Regional Market Access, Value & Evidence Strategy Team, Pricing, Advocacy / Policy, and Legal to drive critical decision making and ensure proper execution.
Lead the development of the payer value story, supported by credible clinical, health economics and PRO messages to justify brand value; interfaces with VESt team to guide evidence generation efforts that support payer value story development.
Leverage understanding of the competitive landscape to anticipate and pre-empt future competitor moves by developing innovative strategies and tactics across Market Access.
Provide input into above brand access initiatives and pull through learnings in branded access strategy.

Qualifications:

Bachelors Degree Required
MBA, MPH, PharmD or Health Economics/Outcomes Research preferred
10 +years of commercial market access experience; 5+ years in rare disease
Substantial US, EU & Emerging Market experience with market access strategies, launch pricing, contracting, reimbursement, and distribution concepts for specialty products
Problem Solving & Innovation - Unstructured strategy development problems that can be logically linked to revenue and profit specific business cases. Examples include LOE strategies, launch strategies, pricing strategies and clinical development strategies.
Proven ability to lead a high performing cross-functional team, and be ready to ‘roll-up-the-sleeves’ to get work done despite conflicting priorities.
Strong written and verbal communication skills
Experience in presenting and communicating to C-suite leaders with exceptional clarity and business focus.
Strong business & scientific acumen, learning agility
Ability to influence & build strong relationships in a matrix environment
Ability to define, track, analyze key access performance measures and make data-driven decisions
Ability to prioritize, pivot, and manage multiple projects simultaneously

About Alnylam

We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

Before applying, please review Alnylam's ⁠Candidate Privacy Notice regarding how Alnylam handles Personal Data you provide with your application for employment.

#LI-ST1 #LI-Hybrid

The pay range below reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).

Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together.

Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers

U.S. Pay Range

$210,000—$284,100 USD

U.S. Pay Range 210000 - 284100 USD

About the Company

Alnylam Pharmaceuticals

Develops RNAi-based therapies for genetic diseases

Alnylam Pharmaceuticals develops RNA interference (RNAi) therapeutics to silence disease-causing genes, aiming to treat rare genetic disorders. Its products work by using RNA molecules that block gene expression, reducing the impact of specific genetic diseases. The company differentiates itself by concentrating on RNAi-based drugs for rare diseases and by building a pipeline through large clinical programs and strategic partnerships, such as commercialization deals in the Gulf States and collaborations with investors. Revenue comes from approved drug sales, licensing agreements, strategic collaborations, and related services like genetic testing and counseling. The company’s goal is to advance and commercialize RNAi therapies to improve outcomes for patients with genetic disorders, expanding its portfolio through partnerships and investments.

Company size: 1,001-5,000
Company stage: IPO
Headquarters: Cambridge, MA
Founded: 2002

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