Full-Time

Principal Engineer

Systems Architecture and Engineering

Confirmed live in the last 24 hours

Flagship Pioneering

Flagship Pioneering

201-500 employees

Biotechnology firm creating health and sustainability solutions

Food & Agriculture
Biotechnology
Healthcare

Senior, Expert

Cambridge, MA, USA

Category
Embedded Engineering
Software Engineering

You match the following Flagship Pioneering's candidate preferences

Employers are more likely to interview you if you match these preferences:

Degree
Experience
Requirements
  • Bachelor’s or Master’s degree in Systems Engineering, Electrical Engineering, Mechanical Engineering, or a related field. A Ph.D. is an advantage.
  • Minimum of 8 years of experience in systems engineering
  • Familiarity with quality management systems such as ISO:9001 is required
  • Proven experience in managing and delivering complex engineering projects successfully.
  • Strong expertise in systems architecture, design, integration, and testing.
  • Exceptional problem-solving skills and the ability to think strategically and creatively.
  • Experience driving technical requirements with vendors, subcontractors, and manufacturers, with excellent communication and documentation skills. (OEM/ODM/JDM/CM)
  • Excellent communication, leadership, and interpersonal skills.
  • Be an independent, solution-driven mindset, adaptable to a fast-changing environment.
Responsibilities
  • Technical project lead responsible for all design and development activities.
  • Build and manage high-performing teams, including hiring, mentoring, and developing talent to foster professional growth and ensure team success.
  • Designing, creating and realizing next-generation platform for FL110’s proteomics solution.
  • Provide systems engineering leadership through a products full development lifecycle, from early stage research to beta testing and product release.
  • Understand and translate customer requirements to design requirements and developing a verification and validation strategy for the platform.
  • Contribute to early stage rapid concept development, prototype and test iterations with cross-functional teams.
  • Work with cross-functional teams to ideate, develop and test subsystem concepts, and develop subsystem architectures.
  • Create, maintain, and update documents for all aspects of the development process as well as contributing to generating intellectual property.
Desired Qualifications
  • A Ph.D. is an advantage.

Flagship Pioneering fosters a culture of groundbreaking advancements in biotechnology, emphasizing an ecosystem approach that synergizes human health and sustainability. Their business model not only focuses on creating transformative products but also incubates leading companies like Moderna and Indigo Agriculture, positioning them at the forefront of scientific innovation and industry leadership. This approach offers employees a unique opportunity to be part of a pioneering team that drives real-world impacts across multiple sectors.

Company Size

201-500

Company Stage

N/A

Total Funding

$10.2B

Headquarters

Cambridge, Maryland

Founded

2000

Simplify Jobs

Simplify's Take

What believers are saying

  • Flagship's collaboration with Cambridge institutes accelerates biotech research and innovation.
  • Strategic partnerships with Pfizer enhance Flagship's capabilities in cardiometabolic and cancer treatments.
  • Flagship's focus on AI-driven platforms aligns with growing trends in drug discovery.

What critics are saying

  • Over-reliance on strategic partners like Pfizer could impact Flagship's projects.
  • Rapid valuation increases may pressure Flagship to deliver similar results across its portfolio.
  • High-profile executive appointments could lead to internal power dynamics and strategic disagreements.

What makes Flagship Pioneering unique

  • Flagship Pioneering creates first-in-category ventures transforming health and sustainability.
  • The company combines science, entrepreneurialism, and capital management for systematic innovation.
  • Flagship's evolutionary methodology navigates from unreasonable propositions to transformational outcomes.

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Benefits

Professional Development Budget

Flexible Work Hours

Company News

CityBiz
Oct 23rd, 2024
Flagship Pioneering Appoints Junaid Bajwa as Senior Partner, Head of United Kingdom,

Flagship Pioneering, the bioplatform innovation company, today announced that Junaid Bajwa, M.D., has joined its London office as Senior Partner and Head of United Kingdom.

PR Newswire
Nov 20th, 2024
Flagship Pioneering Announces Two New Agreements With Ampersand Biomedicines And Montai Therapeutics Under Its Strategic Partnership With Pfizer

Ampersand's AND™ Platform will be used to identify programmed biologics for the treatment of obesity-related targets. Montai's CONECTA™ AI platform will be used to identify small molecules directed to a potential Non-Small Cell Lung Cancer-related target. Collaborations will leverage Pfizer's deep expertise in early discovery and development for cardiometabolic and cancer treatments, two priority therapeutic areas for the company

Endpoints News
Nov 20th, 2024
Exclusive: Former Pfizer commercial chief Angela Hwang to join Flagship

Former Pfizer exec Angela Hwang is joining Flagship Pioneering as a CEO-partner and chief executive of its startup Metaphore Biotechnologies on Jan. 1, the incubator...

PR Newswire
Nov 13th, 2024
Flagship Pioneering Appoints Craig Williams As Ceo-Partner And Chief Executive Officer Of Apriori Bio

Williams was promoted from Operating Partner at Flagship Pioneering and President at Apriori BioApriori Bio has made significant progress in 2024, including securing a collaboration with CEPI, assembling a world class board of directors and building out an early pipeline of prospective vaccinesCAMBRIDGE, Mass., Nov. 13, 2024 /PRNewswire/ -- Flagship Pioneering, the bioplatform innovation company, and Apriori Bio, a biotechnology company aimed at providing humanity with variant-resilient protection against rapidly-evolving viruses, today announced that Craig Williams, MBA, has been promoted to CEO-Partner at Flagship Pioneering and Chief Executive Officer of Apriori

PR Newswire
Jan 23rd, 2025
Flagship Pioneering, Cambridge University Health Partners, And Milner Therapeutics Institute Announce Collaboration To Accelerate Biotech Research And Innovation

First of its Kind Scientific Collaboration Will Engage Top Research Institutes in Cambridge, UK with Flagship PioneeringFocus on Scaling and Advancing Flagship's Breakthrough Science and Technologies through the Cambridge Life Sciences EcosystemLONDON, Jan. 23, 2025 /PRNewswire/ -- Flagship Pioneering, the bioplatform innovation company, today announced an agreement with top life science organisations Cambridge University Health Partners (CUHP) and the Milner Therapeutics Institute (MTI) to collaborate to jointly advance breakthrough scientific research and technologies

Bloomberg
Jan 7th, 2025
Ag Tech Startup Inari Gets $2.17 Billion Valuation in Latest Funding Round

Massachusetts agtech startup Inari Agriculture Inc. said it raised $144 million of new equity at a $2.17 billion valuation, a roughly 32% jump from a prior mark of $1.65 billion set last January.

Genetic Engineering & Biotechnology News
Jan 8th, 2025
Novo Nordisk, Valo Health Ink Expanded Up-to-$4.6B AI Collaboration

The following year, Flagship Pioneering formally announced the launch of privately-held Valo, joining with other undisclosed investors to bring the company's total financing to nearly $100 million.

Contract Pharma
Nov 21st, 2024
Flagship Pioneering Enters Agreements Under Strategic Pfizer Pact

Flagship Pioneering, a bioplatform company, entered agreements with Ampersand Biomedicines and Montai Therapeutics to identify targeted molecules that could be further developed as treatments for obesity and non-small cell lung cancer (NSCLC).

CityBiz
Nov 13th, 2024
Flagship Pioneering Appoints Craig Williams as CEO-Partner and Chief Executive Officer of Apriori Bio

Flagship Pioneering, the bioplatform innovation company, and Apriori Bio, a biotechnology company aimed at providing humanity with variant-resilient protection against rapidly-evolving viruses, today announced that Craig Williams, MBA, has been promoted to CEO-Partner at Flagship Pioneering and Chief Executive Officer of Apriori.