Full-Time

Principal Engineer

Systems Architecture and Engineering

Updated on 3/13/2025

Flagship Pioneering

Flagship Pioneering

201-500 employees

Biotechnology firm creating health and sustainability solutions

No salary listed

Senior, Expert

Cambridge, MA, USA

Category
Embedded Engineering
Software Engineering
Requirements
  • Bachelor’s or Master’s degree in Systems Engineering, Electrical Engineering, Mechanical Engineering, or a related field. A Ph.D. is an advantage.
  • Minimum of 8 years of experience in systems engineering
  • Familiarity with quality management systems such as ISO:9001 is required
  • Proven experience in managing and delivering complex engineering projects successfully.
  • Strong expertise in systems architecture, design, integration, and testing.
  • Exceptional problem-solving skills and the ability to think strategically and creatively.
  • Experience driving technical requirements with vendors, subcontractors, and manufacturers, with excellent communication and documentation skills. (OEM/ODM/JDM/CM)
  • Excellent communication, leadership, and interpersonal skills.
  • Be an independent, solution-driven mindset, adaptable to a fast-changing environment.
Responsibilities
  • Technical project lead responsible for all design and development activities.
  • Build and manage high-performing teams, including hiring, mentoring, and developing talent to foster professional growth and ensure team success.
  • Designing, creating and realizing next-generation platform for FL110’s proteomics solution.
  • Provide systems engineering leadership through a products full development lifecycle, from early stage research to beta testing and product release.
  • Understand and translate customer requirements to design requirements and developing a verification and validation strategy for the platform.
  • Contribute to early stage rapid concept development, prototype and test iterations with cross-functional teams.
  • Work with cross-functional teams to ideate, develop and test subsystem concepts, and develop subsystem architectures.
  • Create, maintain, and update documents for all aspects of the development process as well as contributing to generating intellectual property.
Desired Qualifications
  • A Ph.D. is an advantage.

Flagship Pioneering fosters a culture of groundbreaking advancements in biotechnology, emphasizing an ecosystem approach that synergizes human health and sustainability. Their business model not only focuses on creating transformative products but also incubates leading companies like Moderna and Indigo Agriculture, positioning them at the forefront of scientific innovation and industry leadership. This approach offers employees a unique opportunity to be part of a pioneering team that drives real-world impacts across multiple sectors.

Company Size

201-500

Company Stage

N/A

Total Funding

$10.4B

Headquarters

Cambridge, Maryland

Founded

2000

Simplify Jobs

Simplify's Take

What believers are saying

  • Flagship's collaboration with Cambridge institutions accelerates biotech research and innovation.
  • AI-driven drug discovery complements Flagship's ventures in AI and biotechnology.
  • Flagship's focus on sustainability aligns with the growing importance of sustainable bioengineering.

What critics are saying

  • Increased competition from Trinity Capital may attract talent away from Flagship.
  • Strategic shifts at YourBio Health could impact Flagship's focus or resource allocation.
  • Dependency on Pfizer's expertise may limit Flagship's autonomy in decision-making.

What makes Flagship Pioneering unique

  • Flagship Pioneering systematically creates first-in-category companies in health and sustainability.
  • The company employs an evolutionary methodology to achieve transformational outcomes.
  • Flagship combines innovative capacity, leadership, and capital management in a single enterprise.

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Benefits

Professional Development Budget

Flexible Work Hours

Company News

PR Newswire
Mar 10th, 2025
Flagship Pioneering Unveils Lila Sciences to Build Superintelligence in Science

/PRNewswire/ -- Flagship Pioneering, the bioplatform innovation company, today unveiled Lila Sciences, a company building the world's first scientific...

ABL Advisor
Mar 3rd, 2025
Trinity Capital Expands Life Sciences Presence to East Coast, Appoints Orlando as Managing Director

Trinity Capital announced the appointment of John Orlando as Managing Director of Life Sciences, based in Boston.

Contract Pharma
Feb 19th, 2025
YourBio Health Taps Paul Owen as CEO

Paul Owen has been appointed as Chief Executive Officer of YourBio Health, a pioneer in remote blood collection technology, and CEO-Partner of Flagship Pioneering, a bioplatform innovation company.

PR Newswire
Jan 23rd, 2025
Flagship Pioneering, Cambridge University Health Partners, And Milner Therapeutics Institute Announce Collaboration To Accelerate Biotech Research And Innovation

First of its Kind Scientific Collaboration Will Engage Top Research Institutes in Cambridge, UK with Flagship PioneeringFocus on Scaling and Advancing Flagship's Breakthrough Science and Technologies through the Cambridge Life Sciences EcosystemLONDON, Jan. 23, 2025 /PRNewswire/ -- Flagship Pioneering, the bioplatform innovation company, today announced an agreement with top life science organisations Cambridge University Health Partners (CUHP) and the Milner Therapeutics Institute (MTI) to collaborate to jointly advance breakthrough scientific research and technologies

Genetic Engineering & Biotechnology News
Jan 8th, 2025
Novo Nordisk, Valo Health Ink Expanded Up-to-$4.6B AI Collaboration

The following year, Flagship Pioneering formally announced the launch of privately-held Valo, joining with other undisclosed investors to bring the company's total financing to nearly $100 million.