Full-Time

Postdoctoral Appointee

AI for Biomedical Discovery

Argonne National Laboratory

Argonne National Laboratory

5,001-10,000 employees

Advanced scientific research and computing facilities

Compensation Overview

$72.9k - $121.5k/yr

Company Does Not Provide H1B Sponsorship

Woodridge, IL, USA

In Person

PhD

Category
Biology & Biotech (1)
Required Skills
LLM
Python
TensorFlow
PyTorch

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Requirements
  • Ph.D. completed within the last 0–5 years in computer science, data science, biomedical informatics, computational biology, bioengineering, applied mathematics, electrical engineering, or a related field
  • Strong programming skills in Python and experience developing research or production-quality machine learning software
  • Experience with machine learning or deep learning frameworks such as PyTorch, TensorFlow, JAX, or similar tools
  • Knowledge of federated learning, distributed machine learning, privacy-preserving AI, foundation models, multimodal learning, continual learning, or related areas
  • Ability to design and conduct computational experiments, analyze model performance, and communicate results clearly
  • Experience working with large-scale or complex datasets, including structured, unstructured, multimodal, biomedical, scientific, or high-dimensional data
  • Ability to work independently while contributing effectively to a multidisciplinary research team
  • Strong written and oral communication skills, including the ability to prepare manuscripts, technical reports, presentations, and documentation
  • Ability to model Argonne's core values of impact, safety, respect, integrity, and teamwork
Responsibilities
  • Conduct research and development in federated learning, privacy-preserving machine learning, multimodal AI, and foundation model adaptation for biomedical and related scientific applications
  • Develop new methods for multimodal federated learning that can integrate information across distributed datasets, including imaging, omics, clinical, text, sensor, and other structured or unstructured data modalities
  • Design and implement continuous learning approaches that allow models to improve over time as new data, validation results, or experimental feedback become available
  • Explore agentic AI approaches for federated learning, including AI agents that can assist with task orchestration, experiment planning, model evaluation, workflow automation, and decision support across distributed environments
  • Build and extend software capabilities in federated learning frameworks, with emphasis on scalable, reproducible, secure, and extensible research software
  • Evaluate model performance, robustness, generalizability, fairness, privacy, and data readiness across heterogeneous sites and datasets
  • Contribute to the design of secure AI workflows that may involve trusted research environments, secure enclaves, privacy-preserving computation, differential privacy, secure aggregation, or related techniques
  • Collaborate with interdisciplinary teams, including AI researchers, biomedical scientists, software engineers, security experts, and high-performance computing specialists
  • Prepare research results for publication in peer-reviewed conferences and journals, and communicate findings through presentations, technical reports, project meetings, and software documentation
  • Support project milestones, demonstrations, and deliverables by developing working prototypes, experimental benchmarks, and reusable software components
Desired Qualifications
  • Experience developing or extending federated learning frameworks such as APPFL, Flower, FedML, NVIDIA FLARE, or similar systems
  • Experience with multimodal biomedical data, including combinations of clinical records, medical imaging, pathology, genomics, transcriptomics, proteomics, wearable/sensor data, or scientific text
  • Familiarity with foundation models, large language models, vision-language models, biomedical AI models, or model fine-tuning methods such as LoRA, adapters, instruction tuning, or retrieval-augmented generation
  • Experience with continual learning, active learning, reinforcement learning, closed-loop learning, or human-in-the-loop AI workflows
  • Experience with agentic AI frameworks, tool-using LLMs, workflow orchestration, AI planning systems, or multi-agent systems
  • Familiarity with privacy and security techniques such as differential privacy, secure aggregation, secure multiparty computation, homomorphic encryption, trusted execution environments, or secure enclaves
  • Experience with distributed computing, cloud computing, containers, Kubernetes, Docker, Apptainer/Singularity, or high-performance computing environments
  • Experience with MLOps, reproducible workflows, experiment tracking, CI/CD, software testing, benchmarking, or open-source software development
  • Familiarity with biomedical AI validation, data readiness assessment, model evaluation, regulatory-grade evidence generation, or independent verification and validation workflows
  • Demonstrated ability to publish research, contribute to collaborative software projects, or present technical work to interdisciplinary audiences
Argonne National Laboratory

Argonne National Laboratory

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Argonne National Laboratory advances scientific discovery and sustainability by providing access to large-scale research facilities and high-performance computing for government, academia, and industry partners. Researchers use the Advanced Photon Source for atomic-level materials studies and the Argonne Leadership Computing Facility for complex simulations and data analysis. The lab differentiates itself through its shared-use, multi-institution partnerships and a focus on eco-innovation, net-zero goals, and AI accelerator development. Its aim is to address real-world energy, materials, and data science challenges by combining cutting-edge infrastructure with collaborative research efforts.

Company Size

5,001-10,000

Company Stage

Grant

Total Funding

$19.7M

Headquarters

Lemont, Illinois

Founded

1946

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Simplify Jobs

Simplify's Take

What believers are saying

  • Nvidia and Oracle’s October 2025 partnership brings Solstice and Equinox to Argonne.
  • Minerva arrives in 2026 with 64 Blackwell GPUs, expanding inference capacity.
  • ChemGraph and GridMind in 2026 automate chemistry and grid operations across missions.

What critics are saying

  • DOE’s FY2027 request cuts Argonne funding by $155.8 million, pressuring 2027 programs.
  • Argonne’s $6 billion Genesis center depends on private capital by August 21, 2026.
  • Without Genesis financing, Oak Ridge and commercial clouds can outrun Argonne’s AI leadership.

What makes Argonne National Laboratory unique

  • Aurora, APS, and ALCF combine exascale computing with world-leading synchrotron science.
  • Argonne’s May 2026 inference service gives DOE scientists secure on-prem AI model access.
  • APS Upgrade completed February 2026, reinforcing Argonne’s integrated discovery infrastructure.

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Benefits

Health Insurance

Dental Insurance

Vision Insurance

Life Insurance

Disability Insurance

Paid Vacation

Paid Sick Leave

Paid Holidays

Remote Work Options

Flexible Work Hours

401(k) Retirement Plan

401(k) Company Match

Professional Development Budget

Wellness Program

Growth & Insights and Company News

Headcount

6 month growth

-2%

1 year growth

-3%

2 year growth

-2%
Associated Press
Jul 7th, 2026
Argonne's ChemGraph uses AI to automate computational chemistry workflows

Researchers at the US Department of Energy's Argonne National Laboratory have developed ChemGraph, an open-source framework that uses artificial intelligence to automate computational chemistry workflows. The tool provides a natural language interface, allowing researchers to describe scientific problems in plain language, which the system then maps onto computational tasks and analyses. ChemGraph was developed using resources at the Argonne Leadership Computing Facility, including the Aurora exascale supercomputer. The framework uses AI agents to handle different workflow tasks, from planning to execution and data aggregation. It calls appropriate scientific tools to reduce the risk of AI hallucination, using AI to run physics-based simulations rather than relying solely on existing knowledge. The framework supports applications in combustion efficiency, critical materials, and next-generation batteries, and complements DOE's Genesis Mission to accelerate science through AI.

The Register
May 27th, 2026
Argonne National Laboratory launches private AI inference service using spare supercomputer capacity

The US Department of Energy's Argonne National Laboratory has launched an AI inference service using spare supercomputing capacity to support researchers across DoE labs and the Genesis Mission. The service runs on two clusters: Sophia, with 192 Nvidia A100 GPUs, and Metis, featuring 32 SambaNova SN40L AI accelerators. The platform provides secure access to various large language models, including OpenAI's GPT-OSS, Google's Gemma, and Meta's Llama, through a chatbot-like portal. Researchers are using the service to analyse experimental data in real time, including predicting plasma disruptions in fusion energy research and processing data from particle accelerators and telescopes. Argonne plans to extend the service to its Nvidia GH200-based Tara and B200-based Minerva systems, enabling scientists to experiment with AI without building their own infrastructure.

Business Wire
Mar 26th, 2026
Argonne Lab develops GridMind AI agent to support power grid operators

Researchers at the US Department of Energy's Argonne National Laboratory have developed GridMind, an agentic AI system designed to assist power grid operators through natural language interaction. The system functions as a reasoning co-pilot for control rooms, simplifying complex grid management tasks. GridMind employs a multi-agent architecture where specialised AI agents handle different functions, such as power scheduling and weather-based contingency planning. Large language models coordinate these agents to analyse situations, reason across different tasks and provide explainable recommendations. The system transforms technical analysis into conversational support whilst maintaining rigorous accuracy. Tests on standard power grid models demonstrated that GridMind consistently produced correct results across multiple state-of-the-art language models. The technology aims to accelerate decision-making by integrating disconnected workflows into a coherent reasoning engine.

Yahoo Finance
Mar 11th, 2026
AI adviser helps Argonne's robotic lab discover advanced electronic materials in just 64 experiments

A research team led by the US Department of Energy's Argonne National Laboratory has developed an AI adviser that optimises machine learning algorithms during autonomous experiments, accelerating discovery of advanced electronic materials. The system was applied to Polybot, Argonne's AI-guided robotic laboratory, to investigate mixed ion-electron conducting polymers for wearable electronics and energy storage. The adviser evaluates algorithm performance in real time and communicates insights to scientists who refine experimental plans. It reduced the study to just 64 experiments from over 4,300 possible combinations. During testing, the adviser suggested switching AI algorithms, leading to significant performance improvements, and identified deposition speed as a key performance driver. The research was published in Nature Chemical Engineering and included collaborators from the University of Chicago, Lawrence Berkeley National Laboratory and other institutions.

Argonne National Laboratory
Jun 2nd, 2022
5 clean energy startups chosen for Argonne’s Chain Reaction Innovations - Chain Reaction Innovations

An energy and science incubator for transformative technologies