Senior/Research Associate
Metabolism
Confirmed live in the last 24 hours
NewLimit

11-50 employees

Develops medicines to extend healthspan by reprogramming epigenome
Company Overview
NewLimit is a biotechnology company that stands out for its pioneering work in extending human healthspan by developing medicines to treat age-related diseases through epigenome reprogramming. The company's competitive edge lies in its unique use of functional genomics, pooled perturbation screening, and machine learning models to explore the biology of epigenetic aging and disease on a scale that surpasses its competitors. With a clear 20-year ambition to significantly extend human healthspan and a current focus on restoring function in the aging immune system, NewLimit demonstrates industry leadership and a strong commitment to improving human health.
AI & Machine Learning
Biotechnology

Company Stage

Series A

Total Funding

$40M

Founded

2022

Headquarters

South San Francisco, California

Growth & Insights
Headcount

6 month growth

38%

1 year growth

56%

2 year growth

733%
Locations
San Bruno, CA, USA
Experience Level
Entry
Junior
Mid
Senior
Expert
CategoriesNew
Lab & Research
AI & Machine Learning
Biology & Biotech
Requirements
  • BS in cell biology, endocrinology, molecular biology, or a related natural science
  • 2+ years of work experience in a cell/molecular biology laboratory (academic or industry setting) or PhD in cell biology, endocrinology, molecular biology, or a related field
  • Proficiency in animal handling and husbandry techniques for rodent models (mice or rats)
  • Proficiency with mammalian cell culture
  • Exceptional organizational skills, as demonstrated by detailed record-keeping in lab notebook and an ability to effectively carry out multiple ongoing projects or experiments
Responsibilities
  • Collaborate with our Single Cell Technology, Epigenetic Editing, and Predictive Modeling teams to design, build, and test epigenetic reprogramming interventions for aged and diseased hepatocytes
  • Isolate murine and human hepatocytes using perfusion, FACS, and gradient based approaches
  • Reprogram hepatocytes ex vivo and in vivo
  • Perform experiments in pre-clinical liver disease animal models
  • Perform functional and phenotypic assays to evaluate the effects of reprogramming on hepatocyte biology
Desired Qualifications
  • Proficiency in molecular biology and molecular cloning methods
  • Experience working with mouse models of liver dysfunction
  • Experience with ex vivo culture and manipulation of hepatocytes
  • Experience with single cell genomics methods