Full-Time

Principal Solution Architect

Updated on 8/1/2026

Deadline 7/17/27
Metagenics

Metagenics

1,001-5,000 employees

Science-backed practitioner-focused nutraceuticals and medical foods

Compensation Overview

$180k - $218k/yr

+ Annual incentive program

Jersey City, NJ, USA

Hybrid

Three days on-site per week required.

Category
Sales & Solution Engineering (1)
Required Skills
LLM
ERP
Data Engineering
RAG
Cryptography
Observability
Databricks
Snowflake

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Requirements
  • At least 15 years of experience in enterprise technology, including at least 5 years as a senior- or principal-level architect at a global company.
  • Direct hands-on architectural experience with Microsoft Dynamics 365 Finance and Operations and/or Customer Engagement at scale, including multi-country and multi-legal-entity deployments.
  • Direct experience architecting modern ecommerce platforms; Shopify is strongly preferred, while comparable modern commerce platforms are also considered.
  • Deep understanding of integration architecture, including integration platform as a service platforms, event-driven patterns, and API-first design.
  • Experience architecting modern data platforms such as Microsoft Fabric, Snowflake, Databricks, or comparable platforms.
  • Working knowledge of generative artificial intelligence architecture, including retrieval-augmented generation, agent patterns, large language model routing, evaluations, and guardrails.
Responsibilities
  • Own the enterprise reference architecture across enterprise resource planning, ecommerce, data, integration, and artificial intelligence layers.
  • Set architectural patterns, standards, and technology selection criteria for technology functions.
  • Chair the Architecture Review Board and approve architecturally significant decisions.
  • Serve as the peer-level technical advisor to leaders across enterprise resource planning, ecommerce, data and artificial intelligence, security, and information technology operations.
  • Ensure major transformation programs use consistent integration, data, identity, and observability patterns.
  • Prevent point solutions from becoming new legacy systems.
  • Own the target-state architecture for global enterprise resource planning consolidation onto a single modern platform.
  • Own the target-state architecture for global ecommerce convergence, including business-to-consumer, business-to-business and practitioner commerce, subscriptions, payments, tax, and fulfillment.
  • Own the platform architecture for generative artificial intelligence programs, including large language model routing, retrieval patterns, data pipelines, guardrails, and observability.
  • Rearchitect middleware and integrations across disparate enterprise systems by evolving point-to-point integrations into a governed, event-driven architecture.
  • Set the strategic direction for the enterprise integration platform as major systems converge.
  • Establish separation of concerns so that business logic does not reside in middleware where it does not belong.
  • Define the enterprise data architecture, including master data, event streams, warehousing, and downstream consumption for business intelligence, artificial intelligence, and operational reporting.
  • Establish clear ownership between the transactional stack and the analytical and artificial intelligence stack.
  • Partner with the Head of Security on architecture-level controls covering identity, access, data classification, encryption, and network segmentation.
  • Ensure compliance with applicable regimes, including NIS2, FSSC 22000, ISO 27001, SOC 2, and regional privacy regulations such as GDPR and CCPA.
  • Design for resilience through recovery time and recovery point targets, disaster recovery patterns, and business continuity.
Desired Qualifications
  • Experience in consumer goods, life sciences, or regulated food or manufacturing industries.
  • Direct experience with NIS2, FSSC 22000, ISO 27001, and SOC 2 compliance regimes.
  • Experience with practitioner or healthcare-professional channels and their pricing, payment, and rebate models.
  • Prior experience establishing or scaling a Center of Excellence operating model.

Metagenics develops science-backed nutritional formulas and medical foods sold through a practitioner channel to doctors, chiropractors, and other healthcare professionals who then recommend them to patients. Its products are designed to influence how a person’s genes express themselves through diet, lifestyle, and nutrition, translating scientific validation into clinically guided nutrition plans. The company differentiates itself by focusing on professional-grade products and evidence-based validation rather than consumer-facing marketing, building trust through quality and scientific grounding. Its goal is to support global growth while expanding access to clinician-guided nutrition that can help optimize health outcomes.

Company Size

1,001-5,000

Company Stage

Late Stage VC

Total Funding

$39.1M

Headquarters

Aliso Viejo, California

Founded

1983

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Simplify Jobs

Simplify's Take

What believers are saying

  • HerWellness™ line launched May 2025 addresses hormonal balance across all women's life stages.
  • Symprove acquisition in 2024 expands gut health portfolio leveraging patented water-based delivery system.
  • Patrick Sly named CEO in 2024 brings profit-driven experience from Reckitt's $8B consumer health division.

What critics are saying

  • Symprove outperforms Metagenics in European trust metrics, eroding practitioner gut health dominance within 6-12 months.
  • Undisclosed $310M valuation and debt recapitalization strain capital, hindering future EMEA M&A funding within 12-18 months.
  • Water-based delivery system enables gut colonization preferred by 30% UK clinicians, directly competing with core probiotic efficacy claims in 3-9 months.

What makes Metagenics unique

  • Practitioner channel focus builds trusted brand grounded in scientific validation and quality.
  • Science-backed nutritional formulas and medical foods target doctors, chiropractors, and healthcare professionals.
  • Founded in 1983 by Katke brothers with early premise ahead of consumer supplement trends.

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Benefits

Health Insurance

Dental Insurance

Vision Insurance

Life Insurance

Disability Insurance

Health Savings Account/Flexible Spending Account

401(k) Company Match

Mental Health Support

Paid Vacation

Paid Sick Leave

Paid Holidays

Employee Discounts

Growth & Insights and Company News

Headcount

6 month growth

12%

1 year growth

12%

2 year growth

12%
HormoneSynergy® Clinic, LLC
Feb 21st, 2026
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Natural Practitioner Magazine
Dec 2nd, 2025
Patrick Sly Named Metagenics CEO

Patrick Sly named Metagenics CEO. Metagenics (Aliso Viejo, CA) has named Patrick Sly as CEO, effective immediately. A highly regarded executive in the health and wellness industry, Sly brings a wealth of relevant leadership experience to Metagenics. Current President and CEO Pat Smallcombe, who has led Metagenics through a period of tremendous growth since 2023, will transition to the role of Co-chair of the Board. Metagenics is backed by Gryphon Investors, a leading middle-market private investment firm. "With Patrick's deep experience in medical nutrition, partnerships with health care professionals, and leadership of global businesses, I couldn't imagine a stronger candidate to succeed Pat Smallcombe's successful tenure," said Ryan Fagan, deal partner in Gryphon's Consumer Group. "Patrick's leadership style focuses on integrity, innovation and collaboration, an ideal fit for Metagenics' culture." Sly most recently served as global president of Reckitt's $8 billion consumer health division, where he led the portfolio to industry-leading profitability, renewed market share momentum, and durable growth. He previously served as global president of Reckitt's $3 billion nutrition business, delivering a major global turnaround that strengthened margins, accelerated growth and restored competitiveness. Sly earned his MBA from Washington University in St. Louis' Olin Business School and his Bachelor of Science in Business from Indiana University's Kelley School of Business. "I'm thrilled to be joining Metagenics at such an exciting time," said Sly. "The professional segment of the supplements category has tremendous growth potential, and Metagenics' outstanding brand and clinically tested product line position the company for continued success. I'm especially impressed by the very strong team and solid foundation that Pat Smallcombe has built, and I look forward to working with the organization to drive the next phase of growth."

Rittenhouse Square Chiropractic
Feb 6th, 2024
Metagenics Supplements up to 30% off with an Exclusive Limited Time Offer!Save on Highest-Quality Supplements Available!

That's why Rittenhousechiro has partnered with Metagenics, a trusted brand known for effective products.

Stocks.com.au
Nov 29th, 2023
Calmer Co announces MetaSleep launch using Kavaton extract

Health and wellness specialist The Calmer Co (ASX:CCO) announces US practitioner supplements brand Metagenics has launched MetaSleep: a new product that uses the company's Kavaton extract.

Purety Clinic
Sep 4th, 2023
Metagenics PhytoMulti: Health Benefits and Its Phytonutrient-Rich Blend

Puretyclinic has been working with Metagenics for the past decade and have been highly impressed with their products.