Research Postdoctoral Fellow - Pharmacokinetics Laboratory

Where You’ll Work

Hello humankindness: Join a Legacy of Healing at Saint Joseph’s Hospital and Medical Center (SJHMC) 

Ready to make a real difference? Join SJHMC in Phoenix AZ., a 571-bed nonprofit founded by the Sisters of Mercy over 125 years ago. We're more than a hospital; we're a global destination for life-changing care, embracing patients with humankindness.

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• Barrow Neurological Institute (BNI): A world-renowned center for groundbreaking neurological research and innovative treatments.
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• Culture of Excellence & Well-being: We care for our people, fostering professional and personal growth.
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• Join a Legacy, Shape a Future: Over 20% of our patients travel internationally for our specialized care.

This is an invitation to join a family of dedicated professionals at the forefront of medical innovation, united by the power of humankindness.

Job Summary and Responsibilities

As a Research Post Doctoral Fellow in Pharmacokinetics Laboratory , you will actively engage in laboratory, translational, or clinical research under faculty guidance. Your primary objective is to advance your specialized understanding and practical skills.

Every day you will contribute to ongoing research by conducting experiments, analyzing data, or participating in clinical investigations. This experience aims to build competencies for independent investigative work.

To be successful in this role, you will demonstrate strong foundational knowledge, a proactive research approach, and commitment to developing independence and critical thinking. Aspires to excellence in work quality and quantity. Shows growth technically and intellectually. Contributes to mentor-directed research. Demonstrates capabilities to produce quality original research or clinical care. Develops skills in a research and/or clinical specialty Demonstrates potential to launch an extramurally-funded research program.

The Ivy Brain Tumor Center at Barrow Neurological Institute is a non-conventional non-profit program offering state-of-the-art clinical trials for patients with the most aggressive form of brain cancer. It is home to the largest collection of Phase 0 trials for brain tumors in the world. Our multidisciplinary team of brain tumor specialists and scientists are accelerating drug discovery and precision medicine in neuro-oncology to identify the most promising first-in-class therapies for brain tumor patients.

Job Description: To develop brain targeting therapeutics via rational design and neuro-pharmacokinetic assessment through preclinical and clinical studies.

Principal Duties and Responsibilities: We are looking for an individual to join the Pharmacokinetics (PK) Lab as a postdoctoral associate. The candidate should have a strong background in chemical/pharmaceutical sciences with a reasonable working knowledge of translational research. Candidates who have experience in LC-MS/MS-based method development/validation and can demonstrate competency in pharmacokinetic data analysis will be preferred. The candidate should be able to work well in highly collaborative environment and have excellent communication skills. Potential areas of application include bioanalysis medicinal chemistry drug development drug PK organic synthesis method validation biomarker analysis and PK modeling. The candidate is encouraged to apply for internal and external grants.

Key responsibilities include:
• Development validation and implementation of analytical methods for various drugs drug candidates metabolites and biomarkers employing UHPLC
and LC-MS/MS techniques.
• Performing pharmacokinetic data analyses.
• Manuscript preparation and publishing.
• Supervision and training of laboratory supporting research staff.
• Preparation and delivery of research presentations at local meetings national and international conferences.
• General operation maintenance and troubleshooting of laboratory equipment including UHPLC and LC-MS/MS instruments.
• Preparation and maintenance of required laboratory safety documentation and adherence to the guidelines and regulations in compliance with
CAP/CLIA and HIPAA rules.

Job Requirements

Required

• Ph.D., post-baccalaureate M.D. or D.Sc. degree or equivalent in a relevant field of endeavor
• Laboratory or clinical research at the post-baccalaureate level with an interest in a faculty member's line of study

Preferred

• Doctorate Of Science in a relevant field of endeavor
• Beyond minimum required, experience writing research reports concerning own work and familiarity with a biomedical discipline
• Research experience in organic synthesis bioanalysis medicinal or pharmaceutical chemistry areas.
• Experience with UHPLC or LCMS-based assay development.
• Experience with rational drug design and development physicochemical characterization.
• Experience in biomedical research (cellular techniques and animal handling).
• Experience with maintenance and troubleshooting of LC and MS systems.
• Good organizational and analytical skills.
• Ability to work independently and cohesively as part of a team.

Additional Requirements
• Recommendation letters Education
• Ph.D. or equivalent degree (MD DVM PharmD etc.) in Pharmaceutical Sciences Chemistry Biochemistry Medical Sciences or in related disciplines.