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Arrowhead Pharmaceuticals

Develops RNAi-based gene-silencing therapies

Information Security Analyst 2 - Information Security, Operational Technology

Security Engineering & ArchitectureConfirmed live in the last 24 hours
Full-time$80k - $110k /yrIn-person

About the Job

Requirements

  • A bachelor's degree in Information Security, Information Technology, Computer Science, Industrial Engineering, or a related field, or an equivalent combination of education and experience.
  • At least 3 years of experience in Information Security, System Administration, Help Desk, or similar roles directly supporting OT, ICS, SCADA, or manufacturing environments.
  • Working knowledge of Purdue Enterprise Reference Architecture.
  • Familiarity with ISA/IEC 62443, NIST SP 800-82, NIST CSF 2.0, and CISA guidance for the critical manufacturing sector.
  • Ability to independently manage priorities and drive initiatives to completion.
  • Experience implementing endpoint security controls, system hardening, and configuration management practices.
  • Understanding of vulnerability management, incident response, and security monitoring processes.
  • Knowledge of Windows operating systems, Active Directory, Entra ID, and enterprise networking fundamentals.

Responsibilities

  • Support cybersecurity initiatives for manufacturing and laboratory environments, including ICS, MES, DCS, SCADA, PLC, and connected operational systems.
  • Assist with OT asset inventory, vulnerability identification, risk assessment, and remediation planning.
  • Partner with Engineering and Manufacturing teams to implement security controls within production environments.
  • Participate in network segmentation, secure remote access, and industrial security architecture initiatives.
  • Support cybersecurity assessments of manufacturing technologies and third-party vendor solutions.
  • Monitor emerging threats impacting pharmaceutical manufacturing and industrial control environments.
  • Design, implement, and maintain secure baselines, hardening standards, and compliance policies.
  • Monitor endpoint security posture and coordinate remediation of identified risks and vulnerabilities.
  • Evaluate and implement security controls to improve overall security posture.
  • Support threat detection, incident response, investigation, and remediation activities.
  • Perform security assessments and risk analysis of systems, applications, and infrastructure.
  • Develop and maintain security documentation, procedures, standards, and technical guidance.

Desired Qualifications

  • Cybersecurity experience in OT, Industrial Control Systems, or a manufacturing environment.
  • Experience with Dragos OT, Claroty Platform, Nozomi Networks, Defender for IoT, Fortinet OT Security, Tenable OT, Forescout Vistaro, Armis Centrix, or similar security tools.
  • Certifications relevant to security and compliance.
  • Hands-on experience with an OT-native detection platform.
  • Knowledge of industrial networking technologies.
  • Experience with historians and batch systems.
  • Prior participation in a regulatory inspection.

About the Company

Arrowhead Pharmaceuticals

Develops RNAi-based gene-silencing therapies

Arrowhead Pharmaceuticals develops medicines using RNA interference (RNAi) to silence disease-causing genes. The company’s approach uses a library of RNA chemistries and delivery methods to trigger RNAi, enabling rapid and durable reduction of target gene expression in cells. This gene-silencing strategy aims to treat severe genetic diseases such as cystic fibrosis and hepatitis B by lowering disease-related proteins. Arrowhead’s products are advanced through discovery and development partnerships, licensing deals, and potential commercialization of approved therapies. The company differentiates itself through a broad RNAi platform, proprietary delivery tech, and collaborations with larger pharma firms to advance its pipeline. Its goal is to provide new treatment options for conditions with limited or no effective therapies by translating gene silencing into medicines that can halt or reverse disease progression.

Company size
501-1,000
Company stage
IPO
Headquarters
Pasadena, CA
Founded
2004

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