Full-Time

Principal Mechanical Engineer

Consumables

Confirmed live in the last 24 hours

Cellares

Cellares

201-500 employees

Develops and manufactures cell therapies efficiently

Industrial & Manufacturing
Biotechnology

Compensation Overview

$150k - $240kAnnually

Expert

San Bruno, CA, USA

Category
Manufacturing Engineering
Mechanical Engineering
Required Skills
SolidWorks

You match the following Cellares's candidate preferences

Employers are more likely to interview you if you match these preferences:

Degree
Experience
Requirements
  • 15+ years of hands-on experience with plastic injection molding, including but not limited to component design, design optimization, mold design
  • 5+ years of experience designing and building one-time-use tubing sets or consumables for the medical or biotech industry
  • In-depth knowledge of materials science/plastics properties and metrology techniques
  • Experience with drafting engineering drawings, BOMs, and product specifications
  • Good understanding of DFM and lean manufacturing
  • Excellent verbal, written, presentation, and interpersonal skills. Strong analytical and problem-solving skills
  • Prior experience with FDA regulations and ISO, cGMP, QMS standards & with USP class VI materials
  • Knowledge and hands-on experience with machine shop tools
  • Strong proficiency with SolidWorks CAD tools
  • Work history with several successful iterations of molded components transferred successfully to volume manufacturing
  • Working knowledge of manufacturing techniques, including machining, injection molding, and bonding of consumables (ultrasonic welding, laser welding) for biotech components
  • Desire to be part of a rapidly evolving organization with compelling technology, and ready to take products and processes to the next level
  • Self-awareness, integrity, authenticity, and a growth mindset
Responsibilities
  • Responsible for the design, development, prototyping, and volume manufacturing of complex injection molded assemblies and high-precision mechanical components & assemblies
  • Specifying injection molding tooling with state-of-the-art capabilities: Variotherm, vacuum assist, hot runners, etc
  • Design and development of manufacturing test fixtures as required
  • Identify & interface with key component vendors (suppliers of tubing, valves, etc, that may be integrated into our consumable design)
  • Interface with R&D systems & mechanical engineering teams to negotiate designs that meet product requirements & are feasible to manufacture economically
  • Conduct design reviews and present fresh ideas, new technologies, and creative solutions to design problems
  • Show proof of concept through rapid prototyping
  • Work closely with the scientific team through the creation of verification/validation protocols (IQ, OQ, PQ) as well as successful execution, data generation, reporting, and documentation
  • Work with external companies as needed to outsource injection molding activities and manage the vendors through all phases of the projects, including user requirements, RFQ, vendor selection, and concept & design, followed by verification/validation
  • Work with external companies as needed to outsource consumable assembly and sterilization activities through all phases of the project(s)
  • Create comprehensive work instructions and manufacturing SOPs as needed
Desired Qualifications
  • Desire to be part of a rapidly evolving organization with compelling technology, and ready to take products and processes to the next level
  • Self-awareness, integrity, authenticity, and a growth mindset

Cellares develops and manufactures cell therapies in the biotechnology sector, operating as an Integrated Development and Manufacturing Organization (IDMO). Its proprietary "Smart Factory" technology uses an automated single-use cartridge system, which increases productivity and reduces costs and failure rates compared to traditional methods. The company serves a range of clients, including pharmaceutical companies, and aims to provide efficient and cost-effective manufacturing services for cell therapies. This unique approach sets Cellares apart from competitors that separate development and manufacturing processes.

Company Stage

Series C

Total Funding

$345.3M

Headquarters

South San Francisco, California

Founded

2019

Growth & Insights
Headcount

6 month growth

-1%

1 year growth

0%

2 year growth

0%
Simplify Jobs

Simplify's Take

What believers are saying

  • Partnership with Sony enhances precision in cell therapy manufacturing processes.
  • Strategic partnership with Bristol Myers Squibb provides financial boost and validation.
  • Ossama Eissa's appointment as COO accelerates global expansion and operational capabilities.

What critics are saying

  • Emerging biotech startups threaten Cellares' market share with similar solutions.
  • Potential regulatory delays could impact scaling of new automated systems like Cell Q.
  • Supply chain vulnerabilities may disrupt production timelines for Cell Shuttle and Cell Q.

What makes Cellares unique

  • Cellares' Cell Shuttle offers 10x scalability over manual cell therapy manufacturing.
  • The Smart Factory technology integrates development and manufacturing, unlike traditional CDMOs.
  • Cell Q automates QC processes, addressing bottlenecks in cell therapy quality control.

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