U

University of Chicago

Private research university in Chicago, IL

Principal Researcher

Full-TimeUpdated Deadline 11/20/26
$75k
Senior
Bachelor's, PhD
Chicago, IL, USA
HybridCurrently expected to work in the office at least three days per week.
AI & Machine LearningNatural Language Processing & LLMs

About the job

Requirements
  • A college or university degree in a related field is required.
  • Five to seven years of work experience in a related job discipline is required.
  • By the start date, ABD status or a PhD in a field relevant to the research, such as computer science, artificial intelligence, machine learning, computational linguistics, or a closely related field, is preferred; a PhD is required after one year of employment.
  • Demonstrated experience working with large language models and/or multimodal generative AI systems.
  • Experience designing, implementing, and evaluating applied AI systems in real-world settings.
  • Experience fine-tuning or adapting foundation models.
  • Background with human-centered AI, AI alignment, or safety and guardrail design.
  • Experience building user-facing AI systems or web-based interfaces.
  • Experience working with healthcare data or other high-stakes domains.
  • Ability to work independently with little supervision, identify opportunities for improvement, and recommend effective changes while achieving objectives.
  • Ability to handle multiple detailed tasks or projects simultaneously and meet strict deadlines amid frequent interruptions.
  • Ability to work effectively and diplomatically with colleagues, students, faculty, and corporate contacts through in-person, email, and phone communication.
  • Professional demeanor, including tact, discretion, and a customer-service-oriented approach.
  • Required application documents include a resume or CV, cover letter, two letters of reference emailed directly to the specified contact, and an academic writing sample. Documents must be uploaded through the My Experience page under Application Documents.
Responsibilities
  • Conduct collaborative research with faculty for presentation at academic forums and publication in peer-reviewed academic journals.
  • Collect data and conduct statistical analysis.
  • Conduct literature reviews and perform research.
  • Lead system architecture decisions, model selection, and fine-tuning strategies for the CLARITY AI pipeline.
  • Design and implement end-to-end integration of large-language-model-based text processing with video-generation tools.
  • Develop guardrails to ensure factual accuracy, appropriate communication of uncertainty, and clinical reliability.
  • Lead development of a secure, patient-facing interface that allows patients to access, review, and audit personalized videos.
  • Collaborate with other staff and faculty on the CLARITY project.
  • Design experiments to test prompting strategies and personalization features, and analyze experimental data.
  • Support clinical trial development alongside medical faculty.
  • Use subject matter knowledge and best practices to perform laboratory and research-related duties and tasks, and work independently to assist with project design.
  • Guide data collection, evaluation, and analysis; design and manage databases; and write reports, articles, and manuscripts.
  • Perform other related work as needed.
Desired Qualifications
  • Ability to lead collaborative technical teams.
  • Strong verbal, written, and presentation skills, as well as organizational skills.
  • Strategic planning, critical thinking, analytical, and persuasion skills.

About the company

The University of Chicago is a private research university founded in 1890 in Chicago's Hyde Park neighborhood. It comprises the College, graduate divisions, and professional schools across a broad range of disciplines.

Company Size

N/A

Company Stage

N/A

Total Funding

N/A

Headquarters

N/A

Founded

N/A

Get referred to University of Chicago

See people who can refer or advise you