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AstraZeneca

Global pharmaceutical company developing prescription medicines

Engineering Director - AI Solutions, Enabling Functions

Engineering LeadershipConfirmed live in the last 24 hours
Full-timeBarcelona, SpainNo salary listedIn-person

About the Job

Requirements

  • Significant demonstrated experience building AI applications within a large, regulated enterprise and delivering AI solutions across multiple enabling functions.
  • Significant experience in AI governance, including designing governance frameworks, building governance tooling, and operating in governance roles.
  • Significant hands-on experience in operational resilience for AI systems.
  • Ability to work across multi-jurisdictional data sovereignty, regulatory divergence, and cross-border AI governance.
  • Ability to design and ship multi-agent large language model architectures across multiple model providers.
  • Ability to build retrieval-augmented generation pipelines over enterprise data with single-purpose agents, hallucination guards, and immutable audit logging.
  • Experience with AI governance, regulatory compliance, responsible agentic architecture, human oversight, and lifecycle governance.
  • Experience with software, machine learning, data, and platform engineering leadership.
  • Knowledge of code quality, testing, documentation, peer review, and production-readiness standards.
  • Experience with model serving, data pipelines, API design, integration patterns, security, and observability.
  • Experience driving MLOps maturity, including continuous integration and continuous delivery, automated testing, performance monitoring, incident management, and capacity planning.
  • Experience with data engineering approaches, including pipelines, feature stores, data products, data quality, lineage, and governance.
  • Experience with model-drift and bias monitoring, AI red-team capability, fairness testing, explainability, audit trails, and technical risk management.
  • Ability to lead stakeholder discovery, frame measurable use cases, drive adoption through UX iteration and user feedback, and communicate technical trade-offs to business leaders.

Responsibilities

  • Lead the engineering roadmap for AI across enabling functions, aligning architecture, delivery sequencing, and capability development to business priorities.
  • Set architectural direction for scalable, governed AI platforms designed for modularity, cross-functional reuse, and compliance from the outset.
  • Make high-consequence technical decisions about architecture, build-versus-buy, model strategy, and integration patterns.
  • Build shared components, reusable agent patterns, and common governance instrumentation to accelerate portfolio delivery.
  • Ensure architecture addresses data sovereignty through model routing, data residency, hosting decisions, and cross-border transfer requirements.
  • Shape investment cases for senior stakeholders, explaining engineering decisions in terms of scalability, risk, regulatory defensibility, and value creation.
  • Design and ship multi-agent large language model architectures across model providers, selecting models according to product requirements and compliance constraints.
  • Build retrieval-augmented generation pipelines over enterprise corpora with single-purpose agents, hallucination safeguards, and immutable audit logging.
  • Use AI-assisted development tools to accelerate delivery while keeping architecture decisions, model routing, and guardrails under human control.
  • Lead technical design of solutions across enabling functions, including policy automation, contract risk scoring, procurement analytics, compliance monitoring, financial forecasting, audit analytics, and document intelligence.
  • Establish engineering gates between proof of concept, pilot, and production, measuring against real data and success criteria.
  • Design and operate AI governance structures, including classification and tiering, risk assessment, model registration, approval workflows, monitoring obligations, and decommissioning criteria.
  • Ensure systems meet applicable data protection laws, AI regulations, and sector-specific operational resilience expectations across jurisdictions.
  • Design data-residency and model-routing approaches that respect adequacy arrangements, data-transfer mechanisms, and sovereignty constraints.
  • Design agent systems that gate consequential actions through human oversight and record model decisions, evidence, and audit trails.
  • Embed deterministic classification and routing, human-in-the-loop oversight, model and data cards, and audit trails into engineering practice.
  • Ensure governance tooling supports independent review and separation between building teams and assessment functions.
  • Ensure systems handling financially material, legally privileged, employee-sensitive, supplier-confidential, and audit data meet applicable governance and evidential standards.
  • Own ongoing governance obligations for live AI systems, including periodic reassessment, performance review, change-impact assessment, and documented model-update or retirement decisions.
  • Engineer resilience into AI applications using circuit breakers, provider fallbacks, graceful degradation, fail-safe defaults, and dependency-aware architecture.
  • Design for failures in model providers, data sources, and integration points so user-facing services degrade safely.
  • Map AI systems against the important business services framework, defining impact tolerances, recovery objectives, and tested failover paths.
  • Lead a multidisciplinary engineering team comprising software, machine learning, data, and platform engineers, and recruit, develop, and retain technical talent.
  • Set engineering culture and standards for code quality, testing, documentation, peer review, and production readiness.
  • Develop senior technical contributors and engineering leads, building team depth and succession.
  • Mentor and enable non-technical colleagues across enabling functions to build and ship AI applications and improve AI literacy.
  • Manage team capacity and topology, including structure, specialisation, and balance across discovery, delivery, and sustainment.
  • Drive end-to-end engineering delivery from architecture through production deployment, scaling, monitoring, and lifecycle management.
  • Partner with enterprise technology teams to use shared platforms, infrastructure, and services, and contribute to enterprise capabilities.
  • Establish and enforce standards for model serving, data pipelines, API design, integration patterns, security, and observability.
  • Drive MLOps maturity through continuous integration and delivery, automated testing, performance monitoring, incident management, and capacity planning.
  • Own data engineering approaches for AI across enabling functions, including pipelines, feature stores, and reusable data products.
  • Establish data quality, lineage, and governance standards for sensitive and regulated data.
  • Establish portfolio-wide model-drift and bias monitoring and provide targeted refinement recommendations.
  • Design and operate AI red-team capability to probe and refine model outputs before release and continuously thereafter.
  • Build automated fairness testing, explainability pipelines, and decision audit trails into standard workflows.
  • Own technical risk management across model degradation, data quality drift, dependency risk, and integration risk.
  • Ensure model assurance reporting meets internal audit, technology governance, and regulator expectations.
  • Partner with enterprise technology on shared infrastructure, platform services, tooling, and engineering standards.
  • Identify and scale opportunities to adapt proven solutions across enabling functions.
  • Engage external technology partners to co-develop or integrate capabilities that accelerate delivery or provide specialist functionality.
  • Shape joint partner programs by defining technical scope, integration architecture, and quality standards.
  • Build a scaling model using shared services, external partners, and cross-functional reuse to multiply impact without proportional headcount growth.
  • Serve as a technical partner to functional leaders, advising on AI opportunities, risk, regulatory posture, and investment.
  • Run discovery with business units, identify real problems, define concrete use cases and measurable success criteria, and drive adoption through UX iteration and user feedback.
  • Translate engineering complexity into business strategy by communicating trade-offs, timelines, and constraints.
  • Develop KPI and KRI frameworks that give leaders visibility into usage, quality, and value.
  • Represent enabling functions in enterprise AI leadership forums and architecture governance.
  • Contribute to enterprise AI governance through architecture review boards, AI policy development, and standards evolution.
  • Drive reuse and knowledge sharing by applying governance and resilience patterns across the enterprise.
  • Advocate for enabling-function requirements in enterprise technology planning and platform prioritisation.

About the Company

AstraZeneca

Global pharmaceutical company developing prescription medicines

AstraZeneca develops and markets prescription medicines and vaccines worldwide, with a focus on oncology, cardiovascular/metabolic, respiratory, and infectious diseases. Its products work by targeting specific biological pathways or cells, using small-molecule therapies, biologics, and vaccines to treat diseases or prevent infections. It differentiates itself through its dual heritage from Sweden and the UK, a broad pipeline, and strong R&D and collaborations that move from discovery to patient access. Its goal is to improve people’s health by discovering, developing, and delivering medicines and vaccines to patients worldwide.

Company size
10,001+
Company stage
IPO
Headquarters
Cambridge, United Kingdom
Founded
1913

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