VP, Client and Partner Success

Hybrid (Chicago or Boston)

Ayble Health is on a mission to make life-changing digestive health care accessible and affordable. Ayble is an AI-enabled virtual digestive health clinic providing multidisciplinary care to the 40% of Americans suffering who experience gastrointestinal conditions from occasional symptoms to chronic GI disorders. Backed by 15 peer-reviewed publications, Ayble empowers employers & payers to improve outcomes and reduce cost for GI conditions, which contribute $140B in direct healthcare expenditure.

Ayble is the fastest-growing GI company in the nation. We are building a world-class commercial team and looking for an experienced, mission-driven sales leader to help us grow.

About the role:

We are seeking an exceptional VP of Client and Partner Success to join our team. In this senior leadership role, you will own the post-sale experience and long-term outcomes for Ayble's full portfolio of employer, health plan, and channel partner relationships — driving retention, expansion, and advocacy across our book of business.

You will build and scale the Client and Partner Success function with a retention-first mindset: the team, the playbooks, the systems, and the relationships that ensure every client and partner can demonstrate the value of Ayble to their organizations. You will serve as the executive face of Ayble to our most strategic accounts — including CHROs, VP Benefits, CMOs, and medical directors — and collaborate closely with Sales, Clinical, Product, and Data to ensure we consistently deliver and demonstrate measurable impact.

This role reports directly to the CCO.

Where you will work:

This role is a hybrid role with a strong preference for location in either Chicago or Boston. We value in person collaboration time and will have set days per month to work in the Chicago or Boston offices. There will also be regular travel for client and partner meetings, broker events, and industry conferences (approximately 20–30%).

What you will do:

Build, lead, and mentor a high-performing team of Client Success Managers and Partner Success Managers; define team structure, hiring roadmap, and career development paths as Ayble scales
Own net revenue retention across the full book of business — renewals, upsells, and cross-sells — and forecast accurately against quarterly and annual targets
Own client satisfaction, aiming for “love” rather than “like”
Develop and execute a tiered service model that delivers high-touch support for strategic accounts while scaling efficiently across mid-market clients
Drive member engagement and clinical outcomes in partnership with Ayble's clinical and data teams; translate program performance into compelling client narratives and ROI cases tailored to each buyer
Oversee executive business reviews (QBRs, EBRs) with employer and health plan clients, ensuring stakeholders understand and can articulate Ayble's value & impact
Lead Ayble's relationships with channel partners — including benefits consultants and brokers, benefits navigation platforms, and health plan partners — and build scalable enablement programs so partners can confidently position, launch, and support Ayble in their client base
Serve as the internal champion for client and partner needs — synthesizing feedback, surfacing trends, and influencing product roadmap and clinical program design
Partner closely with Sales to ensure seamless handoffs, inform new business positioning, and support expansion into new verticals and segments
Build and maintain CS infrastructure in Salesforce, including playbooks, health scoring, and renewal forecasting; define the metrics and operating rhythms that drive a healthy, predictable function

The ideal candidate has:

Bachelor's degree and 12+ years of experience in client success, account management, or client services — with at least 5 years in digital health, employer benefits, or healthcare SaaS — and a demonstrated track record of owning and growing a B2B book of business
Experience operating a book of $100M+ ARR with executive accountability for P&L impact
Experience building and scaling a CS team, including hiring, coaching, and performance management
Deep familiarity with the employer benefits and/or health plan ecosystem — you understand how CHROs, benefits teams, and their consulting partners evaluate and renew point solutions
Experience managing channel partner relationships — benefits consultants, brokers, or benefits navigation platforms — and building partner enablement programs that scale
Executive presence and strong communication skills; you're credible and compelling in a boardroom, in a tough renewal conversation, and on a stage
Data fluency — you can work with utilization reports, clinical outcomes data, and ROI models to build compelling narratives and drive client decisions
A desire to be part of a high-performing, high-integrity, mission-driven team that operates with urgency, individual accountability, and a commitment to authentic feedback

Preferred Qualifications:

Experience in the digestive health or chronic condition management space
Background managing health plan channel relationships, including employer-sponsored benefit structures, ASO, and fully-insured models
Experience building CS infrastructure from an early or growth stage — playbooks, health scoring, tooling
2+ years at a venture-backed, high-growth digital health or benefits technology company

Compensation Transparency:

The base salary range is $180K to $220K. Individual compensation will depend on qualifications, skills, and experience. This role is eligible for Ayble's equity incentive program and comprehensive benefits, including flexible PTO, medical/dental/vision coverage, and 401(k) matching.

Equal Employment Opportunity:

Ayble Health is proud to be an Equal Employment Opportunity employer and values diversity in the workplace. We do not discriminate on the basis of race, religion, color, national origin, sex (including pregnancy or related conditions), sexual orientation, gender identity, gender expression, age, disability, veteran status, genetic information, or any other legally protected characteristic. We are committed to providing reasonable accommodations for qualified individuals with disabilities throughout our recruiting process. Please contact us at [email protected] if you need assistance.

About the company

Ayble Health runs an AI-enabled virtual multidisciplinary clinic for chronic digestive and autoimmune diseases. It unites GI doctors, dietitians, behavioral health specialists, pharmacists, coaches, and care coordinators who use proprietary AI tools built on a large GI dataset to guide care. Patients access care through payer, employer, and health-system partnerships with in-network plans, and the team coordinates virtual visits, nutrition plans, behavioral support, and medication management. The company aims to expand AI-guided precision care from GI into adjacent autoimmune areas and grow access and outcomes through data-driven care and expanded provider networks.

Company Size

11-50

Company Stage

Series A

Total Funding

$20.6M

Headquarters

Boston, Massachusetts

Founded

2020

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Simplify's Take

What believers are saying

The September 16, 2026 Series A added $16 million from Neon and strategics.
Amazon access can funnel covered members with under-$10 out-of-pocket costs into enrollment.
Ayble reports 47% symptom improvement within four weeks, supporting employer renewal conversations.

What critics are saying

Oshi Health already markets itself as the only nationwide multidisciplinary GI clinic.
If payers stop reimbursing digital GI in 2027, Ayble loses its distribution engine.
Autoimmune expansion dilutes focus; failure there traps Ayble in narrower GI economics.

What makes Ayble Health unique

Sam Jactel’s IBD-founder credibility anchors Ayble’s product around lived chronic-disease pain.
Ayble’s September 2026 Amazon Health Benefits Connector placement expands discovery inside checkout-like workflows.
Sixteen peer-reviewed studies and PHTI validation separate Ayble from commodity telehealth.

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Benefits

Health Insurance
Dental Insurance
Vision Insurance
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Headcount

6 month growth

1 year growth

2 year growth

MedCity News

Sep 18th, 2026

Ayble Health secures $16M for virtual digestive health clinic.

Ayble Health secures $16M for virtual digestive health clinic. Ayble Health's Series A round was led by Neon, with participation from Unum Ventures, Upfront Ventures, M13, Cleveland Clinic Ventures, DigiTx and Accomplice. Ayble Health, an AI-powered virtual gastrointestinal clinic, announced on Wednesday that it raised $16 million in Series A funding. The Boston-based company treats digestive issues including abdominal pain, bloating, constipation, weight gain and more. It offers access to a care team, nutrition tools, gut-brain behavioral therapy and wellness support. The company serves employers, payers and providers. Ayble Health's Series A round was led by Neon, with participation from Unum Ventures, Upfront Ventures, M13, Cleveland Clinic Ventures, DigiTx and Accomplice. In total, it has raised more than $27 million. We are taking a look at how health insurers are using AI, defining success, and managing cybersecurity risks. Give us your opinions by completing our brief, anonymous survey. "I've been tracking the GI space closely for years, and what Ayble has built is different," said Kimmy Scotti, founding and managing partner at Neon, in a statement. "Having invested early in top digital health companies, I've seen what it takes to build a category-defining company in healthcare. Ayble has spent years building the clinical evidence before they scaled the business. That earns trust from the full ecosystem: health systems, payers, and most importantly, patients, and it's what makes a durable market leader." The financing will be deployed across three main areas, according to Sam Jactel, founder and CEO of Ayble Health. "First, we are advancing our machine learning capabilities to deliver deeper, data-driven personalization across patient enrollment, engagement, and clinical pathways," Jactel told MedCity News. "Second, we are expanding our multidisciplinary care model beyond GI into adjacent therapeutic areas, starting directly with autoimmune conditions like rheumatoid arthritis, psoriasis and autoimmune thyroid disorders. Finally, we are accelerating our commercial footprint to scale access across national health plans, jumbo employers, and key benefit platforms." Currently, GI conditions affect more than 70 million Americans and drive $136 billion in annual U.S. healthcare spending. Autoimmune conditions add about $106 billion a year in direct U.S. healthcare spend. And patients often experience wait times of up to 40 days for specialty visits. presented by What if health plans could identify member decline before an avoidable hospitalization occurs? Real-time clinical visibility into long-stay SNF members uncovers risk earlier and drives better outcomes. In addition, these conditions overlap with other diseases. A 2025 study of 141 million patients found that inflammatory bowel disease was associated with 24 distinct autoimmune conditions. "Traditional healthcare treats these conditions in isolated silos with 10-minute specialty visits," Jactel said. "But as any patient will tell you, chronic conditions don't exist in a vacuum, and they certainly don't stop when you leave the doctor's office. Ayble solves this by building an evidence-based, multidisciplinary model that treats overlapping gut and autoimmune conditions under one unified platform." Other GI companies include Oshi Health, Cylinder Health and Digbi Health.

PR Newswire

Sep 16th, 2026

Ayble Health raises $16M Series A to expand AI-enabled virtual digestive and autoimmune care

Ayble Health, an AI-enabled virtual digestive health clinic, has closed an oversubscribed $16 million Series A round led by Neon. The funding brings the Boston-based company's total capital raised to over $27 million. The company plans to expand its services beyond gastrointestinal conditions into autoimmune health. Ayble now covers 80 million Americans through partnerships with payers, employers, and health systems, and is in-network with most commercial health plans. Ayble's multidisciplinary care model combines GI specialists, dietitians, behavioural health experts, and AI technology. The company has published 16 peer-reviewed clinical studies and reports an average 47% improvement in GI symptoms for patients within four weeks. Founder Sam Jactel, who has inflammatory bowel disease, said the funding will deepen AI precision care capabilities whilst extending services to autoimmune conditions.

PR Newswire

Sep 3rd, 2026

Ayble Health joins Amazon's Health Benefits Connector to expand virtual GI Care Access to millions of Americans.

Ayble Health joins Amazon's Health Benefits Connector to expand virtual GI Care Access to millions of Americans. Sep 03, 2026, 08:30 ET As the first gastrointestinal care provider on Amazon's Health Benefits Connector, Ayble makes it easier for covered customers to discover and enroll with $0 or low out-of-pocket costs* BOSTON, Sept. 3, 2026 /PRNewswire/ - Ayble Health, a leading AI-supported virtual multidisciplinary GI care platform, today announced it has joined Amazon's Health Benefits Connector. The collaboration gives millions of Americans a direct path to discover, verify coverage for, and enroll in specialized digestive healthcare already covered by their health plans[*]. Ayble is the first digestive health provider to be included in Amazon's Health Benefits Connector. In-network for more than 80 million Americans across most major health plans, Ayble delivers expert care leaving most patients with out-of-pocket costs under $10, and even $0*. Through the Health Benefits Connector, individuals can now find out if they're covered - and start care - without navigating complex insurance portals, calling member services, or waiting weeks for an appointment. "We built Health Benefits Connector to help customers discover and use quality health services that may be covered by their insurer," said John Singerling, Head of Strategic Growth and Network Development for Amazon Health Services. "Adding Ayble as our first digestive health provider means customers now have a simple path to specialized, clinician-led GI care, an area where access can be a real challenge." The Access Problem: Gastrointestinal conditions affect more than 70 million Americans, with prevalence ranging from 25% in commercially insured populations to upwards of 50% among Medicare beneficiaries[1]. Despite advances in care, prevalence continues to rise: between 2007 and 2019, the claims-based prevalence of digestive disorders among private insurance enrollees rose 45% and by 9% from 2015 to 2019 for Medicare beneficiaries[1]. Access to specialty digestive care, on the other hand, is constrained and getting tighter: close to 70% of US counties, do not have a single local practicing gastroenterologist[2], and based on GI workforce projections from the Health Resources and Services Administration National Center for Health Workforce Analysis, there is an aggregate shortage of 1,630 full-time GI physicians today[3]. For many patients, that wait means months of unmanaged symptoms, unnecessary ER visits, and avoidable procedures. At the same time, a significant number of Americans already have GI benefits they don't know about or don't know how to use. Amazon's Health Benefits Connector aims to solve this knowledge gap. "One of the biggest barriers to GI care isn't clinical - it's logistical," said Sam Jactel, Founder and CEO of Ayble Health and an Inflammatory Bowel Disease patient himself. "People suffer with digestive symptoms for years, often not knowing that high-quality, multidisciplinary GI care is already a covered benefit under their insurance plans. Joining Health Benefits Connector helps remove that friction and connects people directly to the care they need, at the moment they're looking for help." How It Works: With Amazon's Health Benefits Connector, customers can now: * Discover: Find Ayble through Amazon's Health Benefits Connector when exploring covered health services. * Verify Coverage: Check eligibility instantly to see if their health plan provides digestive health benefits. * Enroll: Register in a few clicks and get matched with a dedicated Ayble care team, available in all 50 states. * Start Comprehensive Care: Access personalized nutrition counseling, medication management, diagnostic testing, and more - powered by Ayble's AI platform and supported by a national network of doctors, nurses, dietitians, behavioral health specialists, and pharmacists. Most patients are matched with a dedicated care team within 48 hours of enrollment. Ayble achieves an average 47% improvement in GI symptoms for its patients, typically within four weeks and sustained for at least a year... About Amazon's Health Benefits Connector: Amazon's Health Benefits Connector helps customers discover and access health programs and services that may be covered by their employer or health plan. Through Health Benefits Connector, customers can check their eligibility, learn about available programs, and connect with care. For more information, visit health.amazon.com. About Ayble Health Ayble Health is a leading clinically-validated GI care platform, delivering personalized, multidisciplinary care to patients with chronic digestive conditions. Recognized by TIME as one of the Best Solutions for GI, Ayble offers ongoing access to specialized care teams - including doctors, dietitians, and behavioral health experts - alongside proprietary technology designed to drive rapid, lasting symptom relief. Backed by 16 peer-reviewed publications and independently evaluated by the Peterson Health Technology Institute and the Validation Institute, Ayble partners with leading employers, health insurance plans, health systems, and community GI practices to scale access to specialty care, reduce healthcare costs, and improve the lives of millions of Americans with chronic digestive diseases. Visit www.ayblehealth.com to learn more. *Coverage, eligibility and out-of-pocket costs vary by insurance plan, state and employer. [1] Unalp-Arida, A., & Ruhl, C. E. (2024). Burden of Digestive Diseases in the United States Population: Rates and Trends. American Journal of Gastroenterology, 120(9), 1987-1997. https://doi.org/10.14309/ajg.0000000000003241[2] Ying X, Yao L, Mathis W, Geographic Disparities in Access to Gastroenterologists in the United States, Gastroenterology, 2025; 168, 1189-1191.e1 [3] Silvestre, J., Singh, G., Kibreab, A. et al. Geographic Disparities in the Supply and Demand of Gastroenterologists Across the United States: Forecasting a National Shortage. Dig Dis Sci 71, 1705-1710 (2026). https://doi.org/10.1007/s10620-025-09558-y; https://bhw.hrsa.gov/data-research/projecting-health-workforce-supply-demand SOURCE Ayble Health, Inc.

JNews

May 9th, 2025

Priority Health Taps Ayble Health to Address GI Disorders

Priority Health, a nonprofit health plan, is teaming up with Ayble Health to provide digestive health support to its members, the companies announced on Wednesday.

Healthcare IT Today

Dec 24th, 2023

Bonus Features - December 24, 2023 - 74% of orgs automating RCM operations, per-physician revenue exceeding expenses at U.S. hospitals, plus 19 more stories

GI care platform Ayble Health is integrating with Commure Engage to make Ayble referrals available through EHRs.

Ayble Health

Vice President of Client and Partner Success

About the job