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Amgen

Makes biotech medicines for serious illnesses

GenAI Engineer

AI Application EngineeringConfirmed live in the last 24 hours
Full-timeLisbon, Portugal€40k - €54.1k

About the Job

Requirements

  • A master's degree with at least 4 years of relevant experience in Computer Science, Information Technology, Engineering, Data Science, or a related field, or a bachelor's degree with at least 6 years of relevant experience in those fields.
  • At least 4 years of professional experience in software development, application engineering, systems integration, or system design.
  • At least 2 years of hands-on experience building, deploying, or supporting production GenAI applications, assistants, agents, Custom GPTs, RAG solutions, or comparable AI-enabled software.
  • Strong hands-on proficiency in Python and experience developing, testing, debugging, and maintaining production applications, APIs, data services, or integration components.
  • Hands-on experience with prompt and context design, embeddings, vector databases or search, retrieval pipelines, structured outputs, tool integration, agent orchestration, evaluation, guardrails, and observability.
  • Experience designing and building cloud-native solutions, preferably on AWS, using services such as Amazon Bedrock, AWS Lambda, Amazon EKS or ECS, API Gateway, IAM, networking, monitoring, and event-driven integration.
  • Experience designing secure RESTful or GraphQL integrations using API gateways, OAuth, service identities, enterprise authentication, role-based access, secrets management, and least-privilege principles.
  • Experience with automated testing, source control, code review, Git-based workflows, CI/CD, and responsible use of AI-assisted software development tools.
  • Experience building modern web applications using TypeScript, React, Next.js, component-driven architecture, state management, design systems, and API integration.
  • Working knowledge of SQL, files, databases, and governed data-access patterns, with troubleshooting and analytical skills across application, model, data, integration, and infrastructure layers.
  • Strong verbal and written communication skills and the ability to produce clear technical documentation.
  • Ability to collaborate effectively with global, distributed, cross-functional teams using agile or scaled agile ways of working.
  • Ability to demonstrate initiative, adaptability, ownership, and self-motivation while delivering high-quality outcomes with appropriate guidance.
  • Ability to manage multiple priorities, assess gaps and fit, communicate technical risks and tradeoffs, and support shared team outcomes.

Responsibilities

  • Design, develop, test, and deploy LLM-powered assistants, agents, Custom GPTs, RAG solutions, APIs, and AI-enabled applications on ChatGPT Enterprise and other approved platforms.
  • Implement prompt and context strategies, structured outputs, embeddings, vector or hybrid retrieval, tool calling, workflow orchestration, and human-in-the-loop controls.
  • Build scalable RAG pipelines that ground responses in trusted enterprise data.
  • Contribute to the GenAI capability roadmap through implementation of MCP-based Apps, ChatGPT Skills, plugins, Workspace Agents, and reusable integration patterns.
  • Develop integration layers and event-driven workflows using APIs, RPA, n8n, and approved orchestration tools to connect systems and trigger agent workflows.
  • Develop reusable Python services, libraries, templates, and evaluation utilities, and contribute TypeScript, React, or Next.js components when required by the solution.
  • Implement automated unit, integration evaluation, and end-to-end tests, along with tracing and monitoring for retrieval quality, response consistency, and reliability.
  • Implement safeguards for prompt injection, data leakage, unauthorized retrieval, insecure tool execution, secrets exposure, excessive agency, and inappropriate model outputs.
  • Apply secure integration and identity patterns using API gateways, OAuth, service identities, delegated authorization, role-based access control, secrets management, least privilege, and user-level auditability.
  • Build and maintain CI/CD pipelines and approved cloud deployment configurations using AWS services, containers, serverless compute, or managed platform capabilities.
  • Troubleshoot defects across application, model, retrieval, data, integration, and infrastructure layers; support incident investigation, remediation, rollback, patching, and performance tuning.
  • Create and maintain technical designs, test evidence, runbooks, deployment instructions, and handover materials that support sustainable operations.
  • Partner with functional teams, product owners, architects, business SMEs, data engineers, platform teams, DevOps, cybersecurity, privacy, and responsible AI stakeholders to translate requirements into reliable solutions.
  • Participate in agile planning, backlog refinement, estimation, demonstrations, retrospectives, release activities, and technical design reviews.
  • Review code and technical designs, apply software engineering standards, and use AI-assisted development tools such as OpenAI Codex or GitHub Copilot with appropriate review, security, and quality controls.
  • Support office hours, technical enablement sessions, junior engineers, and knowledge-sharing through reusable examples, engineering patterns, and lessons learned.
  • Communicate delivery status, technical risks, dependencies, defects, and recommendations to technical and non-technical stakeholders.

Desired Qualifications

  • Experience with OpenAI APIs and SDKs, MCP servers and Apps, ChatGPT Skills, plugins, Workspace Agents, LangChain, LangGraph, n8n, or comparable agent technologies.
  • Experience with Amazon Bedrock and related agent capabilities, AWS Lambda, Amazon EKS or ECS, Amazon EC2, API Gateway, IAM, VPC networking, or event-driven services.
  • Experience with Databricks, Unity Catalog, Vector Search, SQL Warehouses, semantic layers, or governed natural-language-to-SQL solutions.
  • Experience with Power Automate, UiPath, Tableau, Jira, Smartsheet, or comparable automation and delivery tools.
  • Experience with model and application evaluation, red teaming, responsible AI, AI security, GxP, computer-system validation, regulated technology environments, or relevant technical certifications.

About the Company

Amgen

Makes biotech medicines for serious illnesses

Amgen develops and makes biologic medicines, which are drugs built from proteins and antibodies grown in living cells, for serious conditions such as heart disease, cancer, and bone loss. Its anemia drug Epogen, approved in 1989, became one of the biotechnology industry's first blockbuster medicines. Amgen grows these drugs in large tanks called bioreactors, and its products include the cholesterol drug Repatha, the bone-building drug Evenity, and the severe asthma drug Tezspire. It earns money by selling these medicines, mostly through large drug wholesalers that supply hospitals and pharmacies. Amgen was founded in 1980 and is based in Thousand Oaks, California.

Company size
10,001+
Company stage
IPO
Headquarters
Thousand Oaks, CA
Founded
1980

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