Research Associate II / Senior Research Associate
Biomolecular Interaction
Posted on 2/23/2024
INACTIVE
BigHat Biosciences

51-200 employees

AI-driven design of advanced antibody therapeutics
Company Overview
BigHat Biosciences stands out as a leading company in the biotechnology industry, leveraging machine learning and synthetic biology to expedite the antibody engineering process, which could lead to safer and more effective treatments for various diseases. Their unique integration of a high-speed wet lab with AI technologies provides a competitive edge, potentially accelerating the development of next-generation therapies. The company's focus on rational molecular design, as evidenced by their work on advanced antibody therapeutics, underscores their commitment to improving patient safety and treatment efficacy.
AI & Machine Learning
Data & Analytics
B2B

Company Stage

Series B

Total Funding

$99.4M

Founded

2019

Headquarters

San Mateo, California

Growth & Insights
Headcount

6 month growth

11%

1 year growth

55%

2 year growth

171%
Locations
San Mateo, CA, USA
Experience Level
Entry
Junior
Mid
Senior
Expert
CategoriesNew
Lab & Research
Life Sciences
Medical Research
Requirements
  • B.S. with 2+/4+ or M.S. with 1+/3+ years of work experience
  • Experience using label-free biophysical techniques to study antigen-antibody interactions
  • Extensive experience in developing and executing BLI experiments for kinetics, quantitation, and epitope binning
  • Experience developing SPR assays to study antigen-antibody interactions is preferred
  • Good record keeping skills using LIMS and electronic notebooks
  • Excited to work with diverse, cross functional teams to onboard new assays and disseminate results
  • Prior experience with MSD or Gyroslab for multiplexed analyte detection and automation are preferred
  • Prior experience with multi-color flow cytometry is preferred.
Responsibilities
  • Develop and perform kinetic experiments to study antigen-antibody interactions
  • Perform epitope binning and quantitation experiments
  • Develop and onboard kinetic assays for screening antibodies in a high-throughput manner
  • Run multi-analyte ELISA/MSD experiments to identify polyreactive antibodies from discovery campaigns
  • Write and transfer SOPs for used by the production team
  • Keep a detailed record of all experiments using BigHat’s documentation tools, and clearly communicate results and challenges
  • Present experimental plans and results during regular meetings with manager and science teams.