Evidence Generation Manager

ZS is a place where passion changes lives. As a management consulting and technology firm focused on improving life and how we live it, we transform ideas into impact by bringing together data, science, technology and human ingenuity to deliver better outcomes for all. Here you’ll work side-by-side with a powerful collective of thinkers and experts shaping life-changing solutions for patients, caregivers and consumers, worldwide. ZSers drive impact by bringing a client-first mentality to each and every engagement. We partner collaboratively with our clients to develop custom solutions and technology products that create value and deliver company results across critical areas of their business. Bring your curiosity for learning, bold ideas, courage and passion to drive life-changing impact to ZS.

This role will work directly within the Medical & Evidence Generation space, partnering closely with stakeholders across Drug Development, Clinical Operations, Real-World Evidence (RWE), Medical Affairs, Payers, Providers, and Biopharmaceutical organizations to design and execute high-impact strategic and operational initiatives that accelerate evidence generation and improve healthcare outcomes.

What You’ll Do 

• Lead and deliver complex cross-functional engagements across Life Sciences, Biotech, MedTech, and Digital Health clients, ensuring alignment across scientific, operational, commercial, and technology stakeholders
• Drive strategic business development activities, including identifying opportunities, building executive relationships, developing proposals, and expanding client partnerships across R&D, Clinical Development, Medical Affairs, and Evidence Generation
• Serve as a trusted advisor to VP and C-suite client stakeholders, helping shape strategic decisions through data-driven insights and operational execution excellence
• Work directly within the Evidence Generation ecosystem, collaborating with Drug Development, Clinical Operations, Medical Affairs, RWE, payer, provider, and pharmaceutical stakeholders to support evidence strategy and execution
• Manage multi-disciplinary teams across consulting, analytics, technology, operations, and delivery functions, ensuring effective collaboration, accountability, and critical path execution
• Oversee end-to-end project execution, including planning, resourcing, governance, risk mitigation, timeline management, and executive communication
• Leverage AI-enabled and digital collaboration tools to improve delivery visibility, workflow management, proposal development, knowledge sharing, and operational scalability
• Utilize modern project and team management platforms to coordinate delivery activities, monitor milestones, manage dependencies, and enhance execution efficiency across distributed teams
• Lead large-scale Real-World Data (RWD), Real-World Evidence (RWE), Clinical Development, and Prospective Evidence Generation initiatives, translating complex scientific and operational challenges into actionable solutions
• Guide the design and execution of observational studies, evidence strategies, protocol optimization initiatives, and clinical research transformation programs
• Drive innovation in delivery models and operational processes by integrating AI-assisted workflows, advanced analytics, and scalable operating models to improve speed, quality, and client impact
• Mentor and develop consulting teams by fostering a high-performance, collaborative, and growth-oriented culture
• Develop high-quality client deliverables including executive presentations, strategic roadmaps, operational plans, business cases, and thought leadership materials

What You’ll Bring

• MBA, PhD, MD, MPH, or equivalent advanced degree strongly preferred, with demonstrated academic and professional achievement
• 6–10+ years of experience in Life Sciences consulting, pharmaceutical services, clinical operations, evidence generation, healthcare strategy, or related fields
• Demonstrated track record leading cross-functional teams and managing complex client engagements from strategy through execution
• Strong business development and sales experience within Pharma, Biotech, MedTech, or Digital Health organizations, including opportunity shaping, proposal development, and executive relationship management
• Proven ability to manage large programs with multiple stakeholders, competing priorities, and aggressive timelines
• Strong project and program management capabilities, including governance, resource coordination, budget oversight, and critical path management
• Demonstrated experience leveraging AI-enabled and digital productivity tools for team management, project execution, proposal development, workflow automation, reporting, and operational efficiency
• Experience utilizing collaboration and project management platforms to manage distributed teams, streamline execution, and improve delivery transparency
• Ability to integrate AI-assisted workflows into consulting and delivery environments to accelerate decision-making, improve scalability, and enhance client outcomes
• Strong understanding of clinical development, evidence generation, healthcare data ecosystems, payer-provider dynamics, or commercial Life Sciences operations
• Ability to operate effectively within matrixed organizations and lead teams through ambiguity and organizational complexity
• Exceptional executive communication and presentation skills, with the ability to influence senior stakeholders and drive alignment
• Strong analytical and strategic problem-solving skills, balancing high-level strategic thinking with operational detail and execution rigor
• Entrepreneurial mindset with the ability to identify growth opportunities, build new capabilities, and scale client impact
• Proven ability to build trusted

• Fluency in English

• Client-first mentality

• Intense work ethic

• Collaborative spirit and problem-solving approach

How you’ll grow:

• Cross-functional skills development & custom learning pathways
• Milestone training programs aligned to career progression opportunities
• Internal mobility paths that empower growth via s-curves, individual contribution and role expansions

Perks & Benefits:

At ZS, your growth matters. We offer a comprehensive total rewards package that supports your health and well‑being, financial future, time away, and professional development. With robust skills‑building programs, multiple career progression paths, internal mobility, and a deeply collaborative culture, you’ll have the opportunity to do meaningful work, expand your capabilities, and thrive as part of a global community. For details on total rewards in United States, visit ZS US office locations | Where we work | ZS.               

Hybrid working model:

We are committed to giving our employees a flexible and connected way of working.  A flexible and connected ZS allows us to combine work from home and on-site presence at clients/ZS offices for the majority of our week. The magic of ZS culture and innovation thrives in both planned and spontaneous face-to-face connections.

Travel:

Travel is a requirement at ZS for client facing ZSers; business needs of your project and client are the priority. While some projects may be local, all client-facing ZSers should be prepared to travel as needed.  Travel provides opportunities to strengthen client relationships, gain diverse experiences, and enhance professional growth by working in different environments and cultures.

Considering applying?

At ZS, we honor the visible and invisible elements of our identities, personal experiences, and belief systems—the ones that comprise us as individuals, shape who we are, and make us unique. We believe your personal interests, identities, and desire to learn are integral to your success here. We are committed to building a team that reflects a broad variety of backgrounds, perspectives, and experiences. Learn more about our inclusion and belonging efforts and the networks ZS supports to assist our ZSers in cultivating community spaces and obtaining the resources they need to thrive.

If you’re eager to grow, contribute, and bring your unique self to our work, we encourage you to apply.

ZS is an equal opportunity employer and is committed to providing equal employment and advancement opportunities without regard to any class protected by applicable law.

Work Authorization:

This position is not eligible for visa sponsorship. Candidates must have authorization to work in the United States that does not now or in the future require employer sponsorship.

To complete your application:
An on-line application, including a full set of transcripts (official or unofficial), is required to be considered.

NO AGENCY CALLS, PLEASE.

Find Out More At:
www.zs.com