Natera
Genetic testing for cancer, transplant, pregnancy
Clinical Data Operator
On-site position in Austin, Texas.
About the job
- A high school diploma or equivalent is required.
- Zero to one year of industry-related experience is required.
- Previous computer experience is required.
- Training on all product types and the ability to accession samples with accuracy and efficiency are required.
- A typing speed of at least 45 words per minute with high accuracy is required.
- The ability to perform required duties with a high degree of accuracy and attention to detail is required.
- Training relating to HIPAA and protected health information privacy, general policies and procedure compliance, and security must be completed within the first 30 days of hire.
- Current status on Natera training requirements must be maintained.
- Create new orders in the Laboratory Inventory Management System and perform necessary checks to ensure proper accessioning.
- Accession patient samples with high accuracy and efficiency.
- Accurately enter patient data into the Laboratory Inventory Management System.
- Ensure that information in the Laboratory Inventory Management System is up to date.
- Scan test requisition forms and attached paperwork, verify that all paperwork belongs to the patient, and upload it to the case.
- Protect patient health information at all times in compliance with HIPAA and privacy policies.
- Handle blood, buccal, and tissue samples safely and properly.
- Maintain tidy workstations and laboratory areas.
- Maintain familiarity with standard operating procedures and quality standards established by the clinical laboratory.
- Safely and properly handle tools used to open packages and kit boxes.
- Sort packages at the dock when they arrive and bring them to the laboratory.
- Access protected health information in paper and electronic form using the technologies required to perform the job.
- Perform other duties as assigned.
- Previous data entry experience is preferred.
About the company
Natera provides genetic testing and diagnostics using cell-free DNA (cfDNA) from a patient’s blood to guide medical decisions. Its tests include MRD and ctDNA profiling for cancer, the personalized Signatera test, organ transplant health assessment, and Panorama NIPT for prenatal screening. The company combines cfDNA-based results with remote access and genetic counseling to support clinicians and patients. Its goal is to deliver accurate, noninvasive tests that improve treatment decisions and patient outcomes at scale.
Company Size
5,001-10,000
Company Stage
IPO
Headquarters
Austin, Texas
Founded
2004
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Simplify's Take
What believers are saying
- Q2 2026 revenue hit $752.8 million, up 37.7%, and guidance rose to $2.85-2.91 billion.
- Signatera volumes reached 283,000 units in Q2 2026, proving commercial pull across tumor types.
- Japan bladder-cancer launch in 2027 plus EU IVDR access extends Signatera’s addressable market sharply.
What critics are saying
- August 2026 class-action settlement over Panorama closes one reputation wound, not the litigation burden.
- Schneider securities suit, Copley billing claims, and Klein PGT-A litigation keep legal overhang alive.
- ArcherDX’s September 2026 Federal Circuit appeal threatens Natera’s patent moat and future MRD pricing.
What makes Natera unique
- Natera’s Signatera owns tumor-informed MRD with PMDA and FDA bladder-cancer approvals, August 2026.
- June 2026 PMDA approval made Signatera Japan’s first approved MRD test in colorectal cancer.
- Natera combines oncology, prenatal, and transplant testing on one cfDNA platform, widening physician penetration.
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Benefits
Flexible medical plans
Investment options
Time off
Workplace perks
Growth & Insights and Company News
6 month growth
↑ 0%1 year growth
↑ 0%2 year growth
↑ 1%Natera's Signatera test has received regulatory approval from Japan's Pharmaceuticals and Medical Devices Agency as a companion diagnostic for muscle-invasive bladder cancer. The approval supports Signatera-guided decisions for adjuvant atezolizumab treatment and marks the company's second PMDA authorisation for Signatera in three months. Natera plans to commercially launch Signatera for MIBC in Japan in the first half of 2027. The regulatory approval was supported by data from the IMvigor011 Phase III clinical trial, which included more than 20 participating sites in Japan. Bladder cancer affects more than 34,000 people annually in Japan, with approximately 20-25% of newly diagnosed cases classified as MIBC. Following the announcement, Natera stock gained 5.5%.
Natera presents largest MRD dataset in lung cancer at IASLC 2026 world conference. Published on 09/18/2026 at 07:05 am EDT S&P Capital IQ Natera and its collaborators presented four abstracts, including two oral presentations. A mini-oral presentation featured the largest molecular residual disease (MRD) dataset ever presented in lung cancer. This analysis of 1,129 patients with resected stage 1-3 non-small cell lung cancer (NSCLC) spanned an observation period from 2016 to 2025. Signatera MRD detection was evaluated in the early post-surgical window and throughout surveillance, with the following key findings: Early post-surgical Signatera-status was strongly prognostic of recurrence-free survival. Signatera-positivity in the early post-surgical window (7?90 days after surgery) was associated with significantly worse recurrence-free survival (RFS), with a 25% higher absolute 3-year RFS for Signatera-negative patients. Signatera-positive patients had approximately 5X the risk of recurrence or death during surveillance. Findings were consistent across both the primary surgical and perioperative cohorts, supporting broad applicability of Signatera monitoring across resected stage 1-3 NSCLC. Full list of presentations at WCLC 2026 included: Abstract P2.192 Poster: ctDNA After Definitive Therapy +/- Immunotherapy and Association with Survival Outcomes in Locally Advanced Unresectable NSCLC. Abstract P2.200 Poster: ctDNA-based Molecular Residual Disease as a Predictive Biomarker for Treatment Stratification in Unresectable Stage 3 NSCLC. Abstract MO05.07 Mini Oral: KRAS G12C Predicts Superior Outcomes with 1L Cemiplimab for Non-Squamous aNSCLC With PD-L1 = 50%: Data From EMPOWER-Lung 1. Abstract MO11.09 Mini Oral: Post-Surgical Molecular Residual Disease Detection, Adjuvant Treatment Patterns, and Overall Survival in Resected Stage 1-3 NSCLC. (C) S&P Capital IQ - 2026
Natera teams with Angiex on cancer drug trial monitoring. * August 31, 2026 Natera inked a collaboration deal with biotech Angiex to assess the use of its Signatera blood test, which looks for small traces of cancer DNA in patients who have been diagnosed and treated for the disease.
Natera has partnered with Kupando Therapeutics to supply its Latitude tissue-free minimal residual disease (MRD) assay for a Phase 1 immunotherapy trial in multiple skin cancers. The assay will monitor disease and treatment response in patients receiving Kupando's investigational therapy. The collaboration extends Natera's MRD technology into early-stage drug development settings. Natera is a US-based molecular diagnostics company that develops and commercialises testing services. The partnership expands Natera's presence in oncology clinical trials and supports use of its MRD technology across different tumour types. However, the revenue impact from these early-stage trial deployments is likely modest at this stage. Investors will watch whether additional oncology trials adopt Natera's platforms and if the company begins disclosing trial counts or patient volumes linked to MRD collaborations.
Natera reported second-quarter results that beat analyst expectations, driven by strong test volume growth and momentum across its product portfolio. Revenue reached $752.8 million, exceeding estimates by 13.6%, whilst adjusted EPS of -$0.47 beat forecasts. CEO Steven Chapman attributed the performance to record test volumes, particularly for Signatera in oncology, and the launch of an enhanced Panorama prenatal test. The company secured FDA and Japanese regulatory approvals for Signatera during the quarter. Operating margin improved to -10.1% from -20.2% year on year. Sales volumes rose 22.4% compared to the prior year. During the earnings call, analysts questioned the sustainability of Signatera's growth trajectory and future pricing potential. Chapman acknowledged emerging competition in MRD testing but noted that low market penetration leaves substantial room for expansion.