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Illumina

Develops sequencing platforms and consumables

Bioinformatics Scientist/Engineer - DRAGEN Array

Quantitative Biology & BiostatisticsUpdated on Nov 13
Full-time

About the Job

Requirements

  • A PhD in Bioinformatics, Computational Biology, Computer Science, Biostatistics, Bioengineering, or a related field is required.
  • Bring expertise in bioinformatics algorithm development, statistical modelling, and computational genomics, with experience developing production-quality software in scientific or commercial environments.
  • Have experience with array and next-generation sequencing technologies, machine-learning approaches, and scalable software development practices, including testing automation, continuous integration and continuous delivery, and software lifecycle management.
  • Have strong algorithm development and statistical modelling expertise.
  • Have experience with genomic data analysis at scale.
  • Have programming expertise in Python and/or R.
  • Have experience with production software development practices.
  • Have knowledge of testing automation, continuous integration and continuous delivery, and software lifecycle processes.

Responsibilities

  • Lead the design and development of algorithms and probabilistic models for analysis of array and next-generation sequencing data supporting genotyping and genetics applications.
  • Apply statistical, computational, and machine-learning methods to large-scale genetic and epigenetic datasets, including genotyping, sequencing, copy number, and methylation data.
  • Design and develop production-grade software that automates analytical workflows and enables robust analysis at scale.
  • Contribute to and help shape software testing automation, including unit, integration, and regression testing of bioinformatics pipelines.
  • Define and maintain continuous integration and continuous delivery workflows to support continuous integration, validation, and reliable delivery of DRAGEN Array software.
  • Implement and evolve telemetry, logging, and monitoring to improve observability, diagnostics, and operational robustness.
  • Execute and improve Software Lifecycle practices, including requirements traceability, design documentation, verification, and validation.
  • Use JAMA for requirements and traceability and JIRA for planning and execution to support structured, high-quality software development.
  • Collaborate with wet-lab scientists, product management, and engineering teams to translate scientific needs into validated computational solutions.
  • For staff-level candidates, provide mentorship and technical guidance to other scientists and engineers, and contribute to best practices in algorithm design, software engineering, and data analysis.

Desired Qualifications

  • For staff-level candidates, experience providing technical leadership, influencing scientific direction, and mentoring colleagues is valued.

About the Company

Illumina

Develops sequencing platforms and consumables

Illumina develops and sells integrated sequencing systems and the consumables needed to analyze genetic variation and biological function. Its instruments use sequencing-by-synthesis on flow-cell-based platforms, with specialized reagents and library preparation kits that are consumed per run. The company differentiates itself through a broad end-to-end ecosystem, a large installed base that drives repeat purchases, and strategic acquisitions that expand capabilities into multiomics and clinical applications. Its goal is to advance genomic analysis for research and clinical diagnostics to enable personalized medicine and early cancer detection.

Company size
5,001-10,000
Company stage
IPO
Headquarters
San Diego, CA
Founded
1998

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