Full-Time

VP – Medical Affairs

Confirmed live in the last 24 hours

4D Molecular Therapeutics

4D Molecular Therapeutics

201-500 employees

Develops gene therapies for genetic diseases

Biotechnology
Healthcare

Compensation Overview

$336k - $394kAnnually

Senior, Expert

Oakland, CA, USA

Category
Healthcare Administration & Support
Medical, Clinical & Veterinary
Requirements
  • Advance degree (MD, PhD, or PharmD)
  • 10+ years of professional experience within Biotech/Pharma in Medical Affairs
  • 5+ years of people leadership experience
  • An understanding of government and industry guidelines, regulations, laws, etc., for appropriate scientific/medical exchange and communication with customers
  • Ability to lead by example, attract and develop talent, build interdependent partnerships, and create a culture of collaboration and teamwork that fosters open communication, constructive conflict resolution and organizational flexibility
  • Ability to prioritize and manage several complex projects simultaneously
  • Proven ability to develop internal relationships in a highly matrixed environment, as well as external relationships with Key Opinion Leaders and industry experts
  • Ability to communicate effectively at all levels and present complex and/or new ideas with clarity and simplicity
  • Ability to prioritize concurrent projects with tight deadlines and operate in a highly compliance-driven environment
  • Excellent written, verbal, and interpersonal skills, and the ability to communicate at all levels within the company
  • Travel (25-40%) may be required to represent the company at medical conferences, presentations, and other meetings
Responsibilities
  • Lead the Medical Affairs function at 4DMT
  • Develop and implement key Medical Affairs strategies and activities to support the development of our lead assets
  • Develop and present Medical Affairs operational plans to Development and Executive management
  • Represent company externally
  • Direct and oversee all aspects of Medical Affairs and pre-launch needs
  • As a member of the Development Leadership Team, run and continue to build the Medical Affairs function
  • Build and lead a best-in-class global medical affairs team to support launches of 4D-150 and other development candidates multiple indications including, but not limited to, nAMD and diabetic eye disease.
  • Develop key performance indicators and generate analytical reports related to Medical Affairs plans and External Liaison group activities
  • Develop and implement Medical Communication and Disease State Awareness strategies
  • Partner with KOLs to gather information on current focused therapeutic area issues and questions
  • Collaborate with the Commercial team to develop educational material for providers and patients that are balanced and medically accurate
  • Provide direction and input into the development and implementation of successful reimbursement and market-access strategies
  • Work closely with the members of the clinical development and commercial leadership teams to develop the overall strategic direction for 4DMT, evaluate alternative strategies, identify competitive issues, and develop and implement operating plans to achieve company objectives
  • Foster collaborative relationships with academic and clinical experts, publishers, medical and patient associations, and other relevant external and internal stakeholders
  • Develop and manage departmental budgets that effectively achieve desired goals that are balanced with the financial objectives of the broader organization Other duties as assigned, nothing in this job description restricts management’s right to assign or reassign duties and responsibilities to this job at any time
4D Molecular Therapeutics

4D Molecular Therapeutics

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4D Molecular Therapeutics develops gene therapies aimed at treating serious genetic diseases by delivering specific genetic material to patients' cells. The company utilizes a unique technology called Therapeutic Vector Evolution to create adeno-associated virus (AAV) vectors, which act as delivery vehicles for therapeutic genes targeting affected cells in the body. Unlike many competitors, 4DMT focuses on precision medicine for genetic disorders, including cystic fibrosis, and emphasizes rigorous research and clinical trials to ensure the safety and effectiveness of its therapies. The company's goal is to commercialize these gene therapies through direct sales or partnerships with larger pharmaceutical firms, while also securing funding to support its research and development efforts.

Company Stage

IPO

Total Funding

$170.2M

Headquarters

Emeryville, California

Founded

2013

Growth & Insights
Headcount

6 month growth

20%

1 year growth

42%

2 year growth

73%
Simplify Jobs

Simplify's Take

What believers are saying

  • Successful clinical trials, such as the positive interim data from the Phase 1/2 AEROW trial, bolster confidence in 4DMT's therapeutic pipeline.
  • The recent $75 million Series C financing provides substantial capital to advance R&D and clinical programs.
  • The appointment of experienced executives, like Uneek Mehra as Chief Financial and Business Officer, strengthens the company's leadership team.

What critics are saying

  • The biopharmaceutical market is highly competitive, with numerous companies vying to develop similar gene therapies.
  • Regulatory hurdles and clinical trial setbacks, such as the initial clinical hold on 4D-310, can delay product development and commercialization.

What makes 4D Molecular Therapeutics unique

  • 4DMT leverages its proprietary 'Therapeutic Vector Evolution' technology to create advanced AAV vectors, setting it apart from competitors in the gene therapy space.
  • The company's focus on aerosolized genetic medicines, such as 4D-710 for cystic fibrosis, highlights its innovative approach to gene delivery.
  • Strategic partnerships, like the $962M deal with Astellas Pharma, underscore 4DMT's ability to attract significant investment and collaboration opportunities.

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