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Dana-Farber Cancer Institute

Cancer treatment and research institute

Postdoctoral Research Fellow - Valurupalli Lab

Life Sciences ResearchConfirmed live in the last 24 hours
Full-timeBoston, MA, USA$72k - $76.4k

About the Job

Requirements

  • A PhD, MD, or MD/PhD in immunology, cancer biology, molecular biology, chemical biology, biochemistry, cell biology, or a related field is required.
  • A record of productive, rigorous research, including at least one first-author publication or preprint, is required.
  • Strong hands-on experience in mammalian cell culture and molecular biology is required.
  • The candidate must be able to drive a project independently, troubleshoot, and think creatively about experimental design.
  • Excellent written and verbal communication skills are required.

Responsibilities

  • Design, execute, and interpret a program of independent wet-lab research, with mentorship from the principal investigator.
  • Develop and optimize experimental systems, including CRISPR screening platforms, glycoengineered cell models, and immune co-culture assays.
  • Analyze complex, high-dimensional datasets in collaboration with computational scientists, and develop sufficient computational fluency to interrogate personal data.
  • Present results at lab meetings, institutional forums, and national and international conferences.
  • Prepare first-author manuscripts for publication and contribute to collaborative projects.
  • Contribute to fellowship and grant applications and receive support in applying for independent funding, including F32, K99/R00, and foundation awards.
  • Mentor research associates, graduate students, and summer scholars, and contribute to a supportive lab culture.

Desired Qualifications

  • Experience with primary human immune cell culture and functional immune assays, including T cell, NK cell, or macrophage assays.
  • Experience with CRISPR screening, including library design, screen execution, and analysis.
  • Experience with glycobiology, carbohydrate chemistry, or lectin-based methods.
  • Experience with cell surface or proximity-labeling proteomics and mass spectrometry.
  • Experience with antibody engineering, protein engineering, or CAR design.
  • Experience with advanced microscopy, including live-cell or super-resolution imaging.
  • Programming in R or Python for analysis of genomics or proteomics data.

About the Company

Dana-Farber Cancer Institute

Cancer treatment and research institute

Dana-Farber Cancer Institute provides cancer treatment and research services in Boston, serving both adult and pediatric patients. It combines patient care with a broad program of clinical trials and basic, translational, and collaborative research to advance cancer treatments. Treatments include personalized care and access to more than 700 clinical trials, aiming to tailor therapies to the patient’s tumor profile and disease type, often through targeted therapies, immunotherapy, chemotherapy, radiation, and surgical options offered at multiple treatment centers and satellite sites. The Institute differentiates itself through its affiliation with Harvard Medical School and Brigham and Women’s Hospital, its long history of cancer research breakthroughs, nationwide and international reach, and the Jimmy Fund to support patients and research. Its goal is to defeat cancer by delivering expert care while rapidly translating research discoveries into new treatments for patients everywhere.

Company size
5,001-10,000
Company stage
Grant
Total funding
$54.9M
Headquarters
Boston, MA
Founded
1947

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