Nurse Practitioner
About the job
- A Master of Science in Nursing, Post-Master's Certificate, or Doctor of Nursing Practice from an accredited Nurse Practitioner program is required.
- Current national board certification as a Nurse Practitioner through ANCC, AANPCB, or another recognized certifying body is required.
- An active, unrestricted registered nurse and advanced practice registered nurse license in at least five U.S. states is required.
- The candidate must be able to maintain licensure and eligibility for credentialing as required by applicable state laws and organizational policies.
- The candidate must commit to a minimum of 30 hours per week.
- Experience working collaboratively within a multidisciplinary care team is required.
- Experience supporting patients with chronic disease management, behavior change, and longitudinal care is required.
- Familiarity with evidence-based communication strategies, including Motivational Interviewing and other behavior change techniques, is required.
- The candidate must have access to a professional, Health Insurance Portability and Accountability Act-compliant workspace with reliable high-speed internet and a personal computer equipped with a functioning webcam and microphone capable of supporting telehealth visits and virtual collaboration.
- The candidate must be comfortable using telehealth platforms, electronic health records, and digital collaboration tools.
- Demonstrated empathy, strong communication skills, and a patient-centered approach to care are required.
- The candidate must successfully pass background, credentialing, and reference checks.
- Collaborate with a multidisciplinary team of care providers to deliver coordinated, whole-person care.
- Develop individualized care plans that may incorporate nutrition, behavioral health, supplementation, lifestyle modification, medication management, and other evidence-based interventions.
- Evaluate patient symptoms and clinical progress, order and interpret laboratory testing when appropriate, and collaborate with supervising physicians on treatment planning and escalation of care.
- Provide longitudinal support to patients through telehealth visits and asynchronous communication, helping patients implement care plans and achieve their health goals.
- Utilize evidence-based communication and behavior change strategies to promote patient engagement, adherence, and self-management.
- Adhere to evidence-based clinical guidelines and best practices, including those established by the American Gastroenterological Association and American College of Gastroenterology.
- Coordinate care with patients' existing healthcare providers, including sharing clinical information and facilitating referrals or escalation of care when appropriate.
- Deliver care virtually through Ayble's telehealth platform while maintaining high standards of clinical quality, patient engagement, and documentation.
- Contribute to the ongoing development and improvement of clinical workflows, patient education resources, and care protocols.
- Experience caring for patients with chronic gastrointestinal conditions, including IBS, IBD, GERD, Functional Dyspepsia, SIBO, and related disorders.
- Familiarity with evidence-based dietary interventions, such as elimination diets and low FODMAP approaches, and mind-gut therapies or behavioral interventions commonly used in managing chronic gastrointestinal conditions.
- Experience supporting patients through lifestyle modification, habit formation, and sustainable behavior change.
- Telehealth experience.
- Active, unrestricted advanced practice registered nurse licensure in ten or more U.S. states.
- Experience working within a collaborative care model alongside physicians, nurse practitioners, pharmacists, registered dietitians, and behavioral health providers.
- National Society of Health Coaches certification or other formal health coaching training is strongly preferred.
- Educational or professional background in population health, epidemiology, behavioral science, sociology, economics, public health, or related disciplines.
- Experience contributing to clinical protocols, care pathways, quality improvement initiatives, patient education programs, or provider training initiatives.
- Leadership, mentorship, or supervisory experience.
About the company
Ayble Health runs an AI-enabled virtual multidisciplinary clinic for chronic digestive and autoimmune diseases. It unites GI doctors, dietitians, behavioral health specialists, pharmacists, coaches, and care coordinators who use proprietary AI tools built on a large GI dataset to guide care. Patients access care through payer, employer, and health-system partnerships with in-network plans, and the team coordinates virtual visits, nutrition plans, behavioral support, and medication management. The company aims to expand AI-guided precision care from GI into adjacent autoimmune areas and grow access and outcomes through data-driven care and expanded provider networks.
Company Size
11-50
Company Stage
Series A
Total Funding
$20.6M
Headquarters
Boston, Massachusetts
Founded
2020
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Simplify's Take
What believers are saying
- The September 16, 2026 Series A added $16 million from Neon and strategics.
- Amazon access can funnel covered members with under-$10 out-of-pocket costs into enrollment.
- Ayble reports 47% symptom improvement within four weeks, supporting employer renewal conversations.
What critics are saying
- Oshi Health already markets itself as the only nationwide multidisciplinary GI clinic.
- If payers stop reimbursing digital GI in 2027, Ayble loses its distribution engine.
- Autoimmune expansion dilutes focus; failure there traps Ayble in narrower GI economics.
What makes Ayble Health unique
- Sam Jactel’s IBD-founder credibility anchors Ayble’s product around lived chronic-disease pain.
- Ayble’s September 2026 Amazon Health Benefits Connector placement expands discovery inside checkout-like workflows.
- Sixteen peer-reviewed studies and PHTI validation separate Ayble from commodity telehealth.
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Benefits
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0%Ayble Health secures $16M for virtual digestive health clinic. Ayble Health's Series A round was led by Neon, with participation from Unum Ventures, Upfront Ventures, M13, Cleveland Clinic Ventures, DigiTx and Accomplice. Ayble Health, an AI-powered virtual gastrointestinal clinic, announced on Wednesday that it raised $16 million in Series A funding. The Boston-based company treats digestive issues including abdominal pain, bloating, constipation, weight gain and more. It offers access to a care team, nutrition tools, gut-brain behavioral therapy and wellness support. The company serves employers, payers and providers. Ayble Health's Series A round was led by Neon, with participation from Unum Ventures, Upfront Ventures, M13, Cleveland Clinic Ventures, DigiTx and Accomplice. In total, it has raised more than $27 million. We are taking a look at how health insurers are using AI, defining success, and managing cybersecurity risks. Give us your opinions by completing our brief, anonymous survey. "I've been tracking the GI space closely for years, and what Ayble has built is different," said Kimmy Scotti, founding and managing partner at Neon, in a statement. "Having invested early in top digital health companies, I've seen what it takes to build a category-defining company in healthcare. Ayble has spent years building the clinical evidence before they scaled the business. That earns trust from the full ecosystem: health systems, payers, and most importantly, patients, and it's what makes a durable market leader." The financing will be deployed across three main areas, according to Sam Jactel, founder and CEO of Ayble Health. "First, we are advancing our machine learning capabilities to deliver deeper, data-driven personalization across patient enrollment, engagement, and clinical pathways," Jactel told MedCity News. "Second, we are expanding our multidisciplinary care model beyond GI into adjacent therapeutic areas, starting directly with autoimmune conditions like rheumatoid arthritis, psoriasis and autoimmune thyroid disorders. Finally, we are accelerating our commercial footprint to scale access across national health plans, jumbo employers, and key benefit platforms." Currently, GI conditions affect more than 70 million Americans and drive $136 billion in annual U.S. healthcare spending. Autoimmune conditions add about $106 billion a year in direct U.S. healthcare spend. And patients often experience wait times of up to 40 days for specialty visits. presented by What if health plans could identify member decline before an avoidable hospitalization occurs? Real-time clinical visibility into long-stay SNF members uncovers risk earlier and drives better outcomes. In addition, these conditions overlap with other diseases. A 2025 study of 141 million patients found that inflammatory bowel disease was associated with 24 distinct autoimmune conditions. "Traditional healthcare treats these conditions in isolated silos with 10-minute specialty visits," Jactel said. "But as any patient will tell you, chronic conditions don't exist in a vacuum, and they certainly don't stop when you leave the doctor's office. Ayble solves this by building an evidence-based, multidisciplinary model that treats overlapping gut and autoimmune conditions under one unified platform." Other GI companies include Oshi Health, Cylinder Health and Digbi Health.
Ayble Health, an AI-enabled virtual digestive health clinic, has closed an oversubscribed $16 million Series A round led by Neon. The funding brings the Boston-based company's total capital raised to over $27 million. The company plans to expand its services beyond gastrointestinal conditions into autoimmune health. Ayble now covers 80 million Americans through partnerships with payers, employers, and health systems, and is in-network with most commercial health plans. Ayble's multidisciplinary care model combines GI specialists, dietitians, behavioural health experts, and AI technology. The company has published 16 peer-reviewed clinical studies and reports an average 47% improvement in GI symptoms for patients within four weeks. Founder Sam Jactel, who has inflammatory bowel disease, said the funding will deepen AI precision care capabilities whilst extending services to autoimmune conditions.
Ayble Health joins Amazon's Health Benefits Connector to expand virtual GI Care Access to millions of Americans. Sep 03, 2026, 08:30 ET As the first gastrointestinal care provider on Amazon's Health Benefits Connector, Ayble makes it easier for covered customers to discover and enroll with $0 or low out-of-pocket costs* BOSTON, Sept. 3, 2026 /PRNewswire/ - Ayble Health, a leading AI-supported virtual multidisciplinary GI care platform, today announced it has joined Amazon's Health Benefits Connector. The collaboration gives millions of Americans a direct path to discover, verify coverage for, and enroll in specialized digestive healthcare already covered by their health plans[*]. Ayble is the first digestive health provider to be included in Amazon's Health Benefits Connector. In-network for more than 80 million Americans across most major health plans, Ayble delivers expert care leaving most patients with out-of-pocket costs under $10, and even $0*. Through the Health Benefits Connector, individuals can now find out if they're covered - and start care - without navigating complex insurance portals, calling member services, or waiting weeks for an appointment. "We built Health Benefits Connector to help customers discover and use quality health services that may be covered by their insurer," said John Singerling, Head of Strategic Growth and Network Development for Amazon Health Services. "Adding Ayble as our first digestive health provider means customers now have a simple path to specialized, clinician-led GI care, an area where access can be a real challenge." The Access Problem: Gastrointestinal conditions affect more than 70 million Americans, with prevalence ranging from 25% in commercially insured populations to upwards of 50% among Medicare beneficiaries[1]. Despite advances in care, prevalence continues to rise: between 2007 and 2019, the claims-based prevalence of digestive disorders among private insurance enrollees rose 45% and by 9% from 2015 to 2019 for Medicare beneficiaries[1]. Access to specialty digestive care, on the other hand, is constrained and getting tighter: close to 70% of US counties, do not have a single local practicing gastroenterologist[2], and based on GI workforce projections from the Health Resources and Services Administration National Center for Health Workforce Analysis, there is an aggregate shortage of 1,630 full-time GI physicians today[3]. For many patients, that wait means months of unmanaged symptoms, unnecessary ER visits, and avoidable procedures. At the same time, a significant number of Americans already have GI benefits they don't know about or don't know how to use. Amazon's Health Benefits Connector aims to solve this knowledge gap. "One of the biggest barriers to GI care isn't clinical - it's logistical," said Sam Jactel, Founder and CEO of Ayble Health and an Inflammatory Bowel Disease patient himself. "People suffer with digestive symptoms for years, often not knowing that high-quality, multidisciplinary GI care is already a covered benefit under their insurance plans. Joining Health Benefits Connector helps remove that friction and connects people directly to the care they need, at the moment they're looking for help." How It Works: With Amazon's Health Benefits Connector, customers can now: * Discover: Find Ayble through Amazon's Health Benefits Connector when exploring covered health services. * Verify Coverage: Check eligibility instantly to see if their health plan provides digestive health benefits. * Enroll: Register in a few clicks and get matched with a dedicated Ayble care team, available in all 50 states. * Start Comprehensive Care: Access personalized nutrition counseling, medication management, diagnostic testing, and more - powered by Ayble's AI platform and supported by a national network of doctors, nurses, dietitians, behavioral health specialists, and pharmacists. Most patients are matched with a dedicated care team within 48 hours of enrollment. Ayble achieves an average 47% improvement in GI symptoms for its patients, typically within four weeks and sustained for at least a year... About Amazon's Health Benefits Connector: Amazon's Health Benefits Connector helps customers discover and access health programs and services that may be covered by their employer or health plan. Through Health Benefits Connector, customers can check their eligibility, learn about available programs, and connect with care. For more information, visit health.amazon.com. About Ayble Health Ayble Health is a leading clinically-validated GI care platform, delivering personalized, multidisciplinary care to patients with chronic digestive conditions. Recognized by TIME as one of the Best Solutions for GI, Ayble offers ongoing access to specialized care teams - including doctors, dietitians, and behavioral health experts - alongside proprietary technology designed to drive rapid, lasting symptom relief. Backed by 16 peer-reviewed publications and independently evaluated by the Peterson Health Technology Institute and the Validation Institute, Ayble partners with leading employers, health insurance plans, health systems, and community GI practices to scale access to specialty care, reduce healthcare costs, and improve the lives of millions of Americans with chronic digestive diseases. Visit www.ayblehealth.com to learn more. *Coverage, eligibility and out-of-pocket costs vary by insurance plan, state and employer. [1] Unalp-Arida, A., & Ruhl, C. E. (2024). Burden of Digestive Diseases in the United States Population: Rates and Trends. American Journal of Gastroenterology, 120(9), 1987-1997. https://doi.org/10.14309/ajg.0000000000003241[2] Ying X, Yao L, Mathis W, Geographic Disparities in Access to Gastroenterologists in the United States, Gastroenterology, 2025; 168, 1189-1191.e1 [3] Silvestre, J., Singh, G., Kibreab, A. et al. Geographic Disparities in the Supply and Demand of Gastroenterologists Across the United States: Forecasting a National Shortage. Dig Dis Sci 71, 1705-1710 (2026). https://doi.org/10.1007/s10620-025-09558-y; https://bhw.hrsa.gov/data-research/projecting-health-workforce-supply-demand SOURCE Ayble Health, Inc.
Priority Health, a nonprofit health plan, is teaming up with Ayble Health to provide digestive health support to its members, the companies announced on Wednesday.
GI care platform Ayble Health is integrating with Commure Engage to make Ayble referrals available through EHRs.