Full-Time

Director – Cancer Immunology

Confirmed live in the last 24 hours

Revolution Medicines

Revolution Medicines

201-500 employees

Develops targeted therapies for RAS-driven cancers

Biotechnology
Healthcare

Compensation Overview

$195k - $245kAnnually

Senior

San Carlos, CA, USA

Hybrid position requiring in-office presence.

Category
Public Health
Biology Lab & Research
Biology & Biotech
Requirements
  • PhD. degree in immunology, cancer biology or a related discipline with demonstrable track record of excellence in tumor immunology and/or immunotherapy. 2-3 years of post-doctoral and at least 7 years of relevant industry experience in cancer drug discovery and translational research.
  • Proven expertise advancing preclinical and/or clinical evaluation of antibody-directed therapies such as T cell engagers, ADCs or Bispecific.
  • Excellent written and verbal communication skills.
  • Demonstrated ability to multi-task, prioritize options, anticipate challenges, and execute on goals as a member of an interdisciplinary team is extremely important.
  • Thrives in a collaborative team setting and is driven by a desire to be innovative in a high energy, small company environment.
Responsibilities
  • Identify potential novel antibody-directed combination strategies and support internal and external efforts to validate and prioritize these with preclinical proof of concept studies.
  • Scientific input into clinical strategy for RVMD combination with antibody-directed therapy studies.
  • Clinical to preclinical reverse translation: triage emergent I/O-related clinical observations, formulate hypotheses and test as appropriate to further inform clinical development plans and R and D in general.
  • Strategic involvement in external partnering and business development efforts.
  • Help manage a portfolio of research collaborations including establishment of new collaborations with clinical and academic investigators.
  • Partner with the Head of Cancer Immunology to execute on our Cancer Immunology vision and grow and develop a passionate, talented and impactful team.
  • Represent Revolution Medicines at external events including scientific conferences and investigator meetings.

Revolution Medicines develops treatments specifically for cancers caused by RAS gene mutations, which are common in difficult-to-treat cancers like pancreatic, colorectal, and lung cancers. Their main product line includes RASON Inhibitors, designed to target and inhibit RAS proteins that contribute to cancer growth. The company uses a Tri Complex Inhibitor platform to create these specialized therapies. Unlike many competitors, Revolution Medicines focuses solely on RAS-driven cancers, allowing them to carve out a niche in the oncology market. Their goal is to transform cancer treatment by providing effective targeted therapies for patients suffering from these challenging conditions.

Company Stage

IPO

Total Funding

$219.8M

Headquarters

Redwood City, California

Founded

2014

Growth & Insights
Headcount

6 month growth

15%

1 year growth

42%

2 year growth

137%
Simplify Jobs

Simplify's Take

What believers are saying

  • The acquisition of EQRx is expected to add over $1 billion in net cash, significantly bolstering Revolution Medicines' financial position.
  • Successful public offerings and underwriters' full exercise of options have brought substantial capital, indicating strong investor confidence.
  • The company's innovative RASON Inhibitors and Tri Complex Inhibitor platform have the potential to revolutionize treatment for RAS-driven cancers, offering significant clinical impact.

What critics are saying

  • The highly specialized focus on RAS-driven cancers may limit market size and revenue potential compared to broader oncology companies.
  • Integration challenges from the acquisition of EQRx could divert focus and resources, potentially impacting ongoing projects.

What makes Revolution Medicines unique

  • Revolution Medicines focuses exclusively on RAS-driven cancers, a niche but critical area in oncology, unlike broader-spectrum oncology companies.
  • Their Tri Complex Inhibitor platform allows for highly specialized treatments, setting them apart from competitors with more generalized approaches.
  • The company's revenue model, which includes licensing, co-development partnerships, and direct sales, provides multiple revenue streams, enhancing financial stability.

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