U

University of Miami

Research university in Coral Gables, FL

Assistant Scientist

Quantitative Biology & BiostatisticsConfirmed live in the last 24 hours
Full-timeMiami, FL, USANo salary listedIn-person

About the Job

Requirements

  • A Ph.D., M.D., or other doctoral-level degree is required in Statistics, Biostatistics, or Bioinformatics.
  • At least 1 year of full-time experience in biostatistical analysis, bioinformatics, or statistical research methodologies is required, including expertise applying advanced statistical techniques to real-world datasets.
  • Skill in collecting, organizing, and analyzing data.
  • Ability to recognize, analyze, and solve a variety of problems.
  • Ability to exercise sound judgment in making critical decisions.
  • Demonstrated expertise and experience working with clinical trials, observational studies, and animal studies.
  • Experience with omics data, such as genomics, proteomics, and metabolomics, and bioinformatics tools.
  • Proficiency in R programming, including extensive use of R for statistical analysis, data processing, and visualization.
  • A publication record demonstrating contributions to applied statistics and biomedical research.
  • Extensive experience with descriptive statistics, univariate testing, regression models, propensity score matching, meta-analysis, and machine learning methods.
  • Expertise handling large-scale, high-dimensional datasets, including omics data and electronic health records, and skill in data acquisition, integration, and quality assurance for large datasets.
  • Extensive R coding experience, including proficiency in RStudio, RMarkdown, and common Bioconductor packages.
  • Ability to communicate complex statistical concepts to interdisciplinary teams.
  • Ability to mentor junior biostatisticians and support statistical components of collaborative projects.

Responsibilities

  • Contribute to basic and applied research activities and author scientific publications, technical and agency reports, and patent preparations.
  • Collaborate with senior staff to publish findings in refereed journals.
  • Create and conduct experiments and analyze results.
  • Work with other researchers to use and develop end products.
  • Support the Biostatistics component of BBSR on statistical aspects of Cancer Center research related to clinical trials, epidemiologic studies, and laboratory-based investigation.
  • Assist in designing research projects, including specifying hypotheses, calculating sample size and power, planning randomization, and developing statistical analysis plans.
  • Perform data management tasks, including dataset creation, cleaning, verification, and database management.
  • Conduct complex statistical analyses on observational studies and clinical trials, applying regression models, multiple imputation, nonparametric methods, Bayesian methods, and predictive-model development and validation.
  • Implement bioinformatic pipelines and analyze data for omics studies, including genotype data, bulk and single-cell RNA sequencing data, high-dimensional phenotype data, pathway and functional analysis, network analysis, and polygenic risk score derivation and validation.
  • Provide statistical expertise in data visualization, study design, and simulation studies. Develop R or Python scripts for data analysis, statistical modeling, and machine learning, ensuring reproducibility and efficiency.
  • Implement and optimize computing workflows using high-performance computing clusters.
  • Consult statistically with collaborators, present findings, and address statistical inquiries.
  • Contribute to manuscript and grant preparation and revisions by drafting statistical methods and results sections, verifying numerical results, and creating tables and figures.
  • Communicate with the supervisor and collaborators; present analysis results during meetings; contribute to written reports, oral presentations, grant applications and renewals, and publications of research projects.
  • Remain current with statistical methodology applicable to cancer studies and incorporate useful advances into practice.
  • Serve as a member of the Cancer Center's Protocol Review Committee and Data Safety and Monitoring Committee.
  • Adhere to University and unit-level policies and procedures and safeguard University assets.

Desired Qualifications

  • Experience in gene differential expression analysis, bulk and single-cell RNA sequencing data analysis, genome-wide association studies, phenome-wide association studies, and metabolome-wide association studies.
  • Experience with Linux servers and computing clusters.

About the Company

University of Miami

Research university in Coral Gables, FL

The University of Miami is a private research university focused on education, discovery, and service, with undergraduate, graduate, and professional programs.

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