Pharvaris

Develops oral bradykinin B2 antagonists

Medical Science Liaison

Biology & BiotechConfirmed live in the last 24 hours

Full-timeSan Francisco, CA, USA

About the Job

Requirements

A doctorate-level degree (MD, PharmD, or PhD) is preferred, or a master's degree (MPH or equivalent) with at least 3 years of relevant clinical or therapeutic experience.
3–5 years of Medical Science Liaison experience, emphasizing rare diseases, field-based scientific exchange, and/or clinical trial support.
Therapeutic-area and/or hereditary angioedema expertise is preferred.
Frequent travel is required, with availability to travel 80% of the time, including weekends and holidays.
Establish credible, long-lasting relationships and engage respectfully and professionally.
Demonstrate personal accountability, ownership, continuous performance improvement, and operational excellence for colleagues and customers.
Act on patient needs.
Exchange scientific ideas effectively with key opinion leaders and colleagues, and present scientific and medical data to small and large audiences.
Maintain in-depth therapeutic competency and expertise in the leading science for designated disease states, assigned disease areas, and products.
Manage challenging conversations and handle objections.
Focus on patient and customer needs.
Work effectively in in-person and virtual settings.
Use effective listening skills.
Build relationships and identify and responsibly advance opportunities for scientific exchange in focus disease areas.
Work effectively on multidisciplinary teams.
Partner and collaborate appropriately with research and development, commercial, and other internal functions.
Demonstrate strong written and verbal communication skills.
Demonstrate strong leadership and influencing skills.
Demonstrate motivation, self-direction, innovative and strategic thinking, resilience, flexibility, and the ability to plan, manage, and prioritize multiple projects independently.
Stay current with applicable pharmaceutical guidelines and regulations, including ICH, GCP, PhRMA, DOJ, OIG, R&D Code of Ethical Practices, and company policies.
Have above-average computer skills, including Microsoft Office and databases.
Hold a clean and valid driver's license.

Responsibilities

Serve as the field-based extension of the Medical Affairs Team, with field-based activities expected to comprise more than 80% of MSL responsibilities.
Identify scientific exchange needs of key opinion leaders, investigators, and other patient-care stakeholders; establish professional relationships; provide scientific expertise; and liaise with Medical, Clinical Development and Operations, and external partners.
Ensure compliant communication and education on the product portfolio to meet key customers’ educational and professional needs.
Respond effectively to requests for scientific exchange.
Support the design and implementation of scientific programs with external experts and Global Medical Affairs.
Support local team disease-area and product knowledge through scientific training.
Maintain expertise in relevant disease areas and MSL best practices.
Build and maintain professional relationships with external stakeholders through scientific exchange, expanding research, advisory, and educational partnership opportunities.
Develop and maintain peer-to-peer scientific relationships with thought leaders in healthcare, academia, payer, and government organizations according to territory plans and stakeholder requests, including managing strategic scientific partnerships and scientific exchange.
Provide scientific liaison support to investigators involved in interventional or observational studies and investigator-sponsored research.
Provide scientific exchange and appropriate support to payer organizations.
Serve as a liaison between healthcare professionals and Medical Affairs.
Facilitate individual and group scientific interactions with healthcare professionals.
Participate in key opinion leader and healthcare professional planning.
Maintain stakeholder plans and update the medical customer relationship management system accurately, promptly, and compliantly.
Maintain awareness of internal and external information sources that support high-quality scientific exchange, and coordinate interactions between those resources and external customers.
Respond within defined timelines and quality standards to unsolicited inquiries referred to Global Medical Affairs; forward adverse-event reports according to company policy.
Support development of appropriate responses to unique inquiries, including presentations of scientific evidence and medical education.
Present clinical and disease-state information to key opinion leaders, medical advisors, formulary decision-makers, and other healthcare professionals.
Ensure fair, balanced, and non-misleading scientific exchange with healthcare professionals.
Serve as a scientific resource at assigned medical, scientific, and patient advocacy conferences.
Conduct therapeutic training for Sales and Medical colleagues upon request.
Communicate key medical insights from stakeholders to inform medical strategy.
Gather customer insights and organize advisory boards to obtain feedback from external stakeholders.
Provide scientific input and participate in local medical and cross-functional initiatives.
Provide field-based medical support for clinical research programs, registries, and the investigator-sponsored research process.
Provide scientific support for company-sponsored meetings under Medical Affairs leadership.
Participate in internal project teams as directed by Medical Affairs leadership.
Ensure medical activities align with industry and company compliance and regulatory standards, policies, and regulations.
Develop Medical Affairs standard operating procedures and policy guidance documents, and actively support development of cross-functional policy resources.

Desired Qualifications

Therapeutic-area and/or hereditary angioedema expertise.
A doctorate-level degree (MD, PharmD, or PhD).

Pharvaris is a late-stage biopharmaceutical company developing novel, oral bradykinin B2 receptor antagonists to potentially address all types of bradykinin-mediated angioedema. By targeting this clinically proven therapeutic target with novel, oral small molecules, the Pharvaris team is advancing new alternatives to injected therapies for the prevention and treatment of hereditary angioedema (HAE) attacks, and other bradykinin B2-receptor-mediated indications. HAE is a rare and potentially life-threatening genetic disease and people living with HAE can suffer sudden and prolonged attacks of swelling in multiple areas of the body, including the airway, which can be life-threatening.

We are expanding our U.S. Medical Affairs team and are looking for a Medical Science Liaison to join our team and report to our Head of MSLs North America

We have a culture built on the core values of considering others carefully, leading with trust, ensuring rigor and diversity of thought, and contributing freely.

Our company is driven by individuals committed to developing breakthrough therapies which can have a real impact on people’s lives. If you are looking for a place where your work can have meaning, and you can make a difference – Pharvaris is the place for you!

Location
This is a field based medical affairs role

Responsibilities:

Serve as the field-based extension of the Pharvaris’ Medical Affairs Team
Field-based activities expected to comprise >80% of MSL responsibilities.
Systematically identify the scientific exchange needs of Key Opinion Leaders (KOLs), investigators and other stakeholders in patient care, establish strong professional relationships, provide credible scientific expertise and serve as a liaison to Pharvaris North America’s Medical, Clinical Development/Operations and external partners.
Ensure compliant communication and education of Pharvaris’ product portfolio to meet the educational and professional needs of Pharvaris’ key customers.
Responds effectively to requests for scientific exchange.
Support design and implementation of scientific programs with external experts and Global Medical Affairs
Support local team disease area and product knowledge through scientific training.
Maintain personal expertise in relevant disease areas and MSL best practices

KOL/HCP Relationship Management:

Through appropriate scientific exchange, builds and maintains professional relationship with external stakeholders to expand Pharvaris’ research, advisory and educational partnership opportunities.
Ensures high standard of professionalism to develop and maintain “peer-to-peer” scientific relationships with key thought leaders in healthcare, academia, payer, and government organizations per strategic territory plans and as requested by KOLs/HCPs, including the management of strategic scientific partnerships and scientific exchange.
Provide scientific liaison support to Investigators currently involved in Pharvaris’ interventional or observational studies and investigator-sponsored research
Provide scientific exchange and appropriate support to payer organizations.
Serve as a liaison between HCPs and Pharvaris medical affairs.
Facilitate 1:1 and group scientific interactions with healthcare professionals.
Participate in KOL/HCP planning.
Maintain KOL/HCP plans and update medical customer relationship management system in a timely, accurate and compliant manner.
Maintain awareness of and access to internal and external information sources available to support high-quality scientific exchange, and coordinate high-quality interactions between these resources and external customers

Effective and Compliant Dissemination of Data

Respond within defined timeline and quality standards to unsolicited inquiries from HCPs and other stakeholders received by Medical Affairs and referred to Global Medical Affairs by other Pharvaris functions, forwards reports of adverse events according to Pharvaris’ policy.
Support development of appropriate responses to unique inquiries as required, such as the presentation of scientific evidence and medical education.
Presents clinical and disease state information to a variety of audiences, including KOLs, Medical advisors, formulary/decision makers and other HCPs.
Ensures appropriate scientific exchange with HCPs by fostering fair and balanced medical and scientific communications that are not misleading.
Serves as scientific resource at key medical, scientific, and patient advocacy conferences as assigned.
Conducts therapeutic training for Sales and Medical colleagues upon request

Contribute to Pharvaris Strategic Medical Strategy

Communicate key medical insights from KOLs/HCPs to inform refinement of medical strategy.
Gain customer insights, opinions and organization of advisory boards to gain invaluable feedback from external stakeholders
Provide scientific input and participate in local medical and cross-functional initiatives.
Provide field-based medical support to Pharvaris’ clinical research programs, registries, and facilitation of Investigator-sponsored Research process.
Under the guidance of Medical Affairs leadership, provide scientific support for company-sponsored meetings.
Participate on internal project teams as directed by Medical Affairs leadership
- Ensure alignment of medical activities with industry and Pharvaris Compliance and Regulatory standards, policies, and regulations.
- Develop medical affairs standard operating procedures and other policy guidance documents and provide active medical support to development of cross-functional policy resources

Requirements

Doctorate level (MD, PharmD, PhD) preferred or master’s degree (MPH or equivalent) with at least 3 years of relevant experience clinical or therapeutic experience.
3- 5 years of MSL experience with primary emphasis on rare diseases and field-based scientific exchange and/or clinical trial support
Therapeutic area and/ or hereditary angioedema expertise preferred.
Frequent travel is required. Availability to travel 80% of the time, including weekends and holidays
Establishes credible and long-lasting relationships and has personal impact through engaging respectfully and professionally.
Focus on personal accountability and ownership – constantly challenging oneself to take responsibility for continuous performance improvement and operational excellence, reliable and predictable for colleagues and customers.
Act on the needs of patients
Able to exchange scientific ideas and information openly and effectively with key opinion leaders and with colleagues, excellent presentation skills of scientific and medical data to small and large audiences.
Demonstrates in-depth therapeutic competency and expertise of the leading science in designated disease state; maintain knowledge base and scientific expertise on all assigned Pharvaris disease areas and products.
Able to manage challenging conversations and handle objections.
Focus on patient and customer needs.
Able to work effectively in various settings: In-person and/or virtual.
Effective listening skills
Capable of building relationships and focused on identifying and responsibly advancing opportunities for scientific exchange within focus disease areas.
Ability to work effectively on multi-disciplinary teams.
Ability to partner and collaborate appropriately with R&D, Commercial, and other internal functions.
Superior written and verbal communication skills
Strong leadership and influencing skills.
Has a winning attitude and demonstrates a commitment to goals and to Medical/MSL team with a positive approach to problems, even in the face of adversity.
Highly motivated and self-directed with ability to think innovatively & strategically, skillfully plan, manage and prioritize multiple projects independently; demonstrates resilience and flexibility.
Stay current and knowledgeable of applicable pharmaceutical guidelines and regulations, including, but not limited to, ICH, GCP, PhRMA, DOJ, OIG, R&D Code of Ethical Practices and company policies.
Above average computer skills (MS Office, databases, etc)
Clean and valid driver’s license

Pharvaris is committed to fair and equitable compensation practices. The base salary range for this role is $210,000-$230,000 per year. Actual compensation will depend on various factors, including but not limited to depth of experience, skill set, overall performance, and education. Pharvaris believes in providing a competitive compensation and benefits package. Base salary is just one component of our competitive total rewards strategy. In addition to compensation, this role offers the unique opportunity to help build and shape an early‑stage commercial organization, meaningful ownership through equity, annual performance incentives, and flexible paid time off. We encourage candidates who are motivated by the full opportunity and alignment with our mission to apply.

About the Company

Pharvaris

Develops oral bradykinin B2 antagonists

Pharvaris develops oral medications aimed at treating hereditary angioedema (HAE) and other bradykinin B2 receptor–mediated conditions. Its main focus is discovery and development of novel oral bradykinin B2 receptor antagonists that patients can take by mouth rather than by injection. The products work by blocking the bradykinin B2 receptor, which helps reduce or prevent swelling associated with these rare disorders. This approach sets Pharvaris apart from many current therapies that require injections, offering a convenient alternative for patients. The company operates in the clinical-stage biopharmaceutical space, pursuing regulatory approval and eventual commercialization of its oral therapies. Pharvaris’ goal is to provide effective, easier-to-use treatments that improve patient choice and quality of life for people with rare disease conditions.

Company size: 51-200
Company stage: IPO
Headquarters: Leiden, Netherlands
Founded: 2015

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