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Rhythm Pharmaceuticals

Commercializes MC4R-targeted therapies for rare obesity

Medical Science Liaison Senior Manager

Biology & BiotechConfirmed live in the last 24 hours
Full-timeLos Angeles, CA, USA

About the Job

Requirements

  • An advanced scientific or clinical degree (PharmD, PhD, MD, or DO) is strongly preferred; candidates with a Doctor of Nursing Practice degree and relevant clinical experience in obesity, endocrinology, genetics, or neurology will also be considered.
  • At least 6 years of experience in the pharmaceutical, biotechnology, healthcare, or a related industry.
  • Understanding of healthcare systems, patient care pathways, and the evolving medical landscape in the assigned territory or region.
  • Working knowledge of applicable regulations, industry guidance, and ethical standards governing Medical Affairs activities, including GCP, ICH, PhRMA Code, OIG guidance, and company policies.
  • Scientific acumen and ability to critically evaluate, interpret, and communicate complex clinical and scientific information to diverse audiences.
  • Ability to develop and maintain credible, trusted relationships with key opinion leaders, investigators, healthcare professionals, and other external stakeholders.
  • Insight-generation and strategic thinking capabilities, including translating field observations into meaningful insights, implications, and actionable recommendations for medical strategy and organizational decision-making.
  • Ability to work effectively within a cross-functional matrix environment, provide medical expertise, and foster collaboration toward shared medical and organizational objectives.
  • Adaptability and resilience to navigate change and ambiguity and adjust priorities to evolving organizational and healthcare needs.
  • Communication, presentation, and facilitation skills, including experience leading scientific discussions, educational programs, and training sessions.
  • Organizational, project management, and territory planning skills.
  • Willingness and ability to travel frequently; the role requires 50–75% travel, easy access to transportation and airports, and a Los Angeles base.

Responsibilities

  • Serve as a trusted scientific partner to key external experts by delivering timely, evidence-based, impactful scientific exchange that advances understanding of the scientific and clinical value of Rhythm’s research and therapies.
  • Develop and execute strategic engagement plans with key opinion leaders and healthcare professionals to support implementation of Rhythm’s medical strategy.
  • Gather and communicate actionable medical insights with clear implications and recommendations from key opinion leaders, healthcare professionals, and healthcare systems to inform medical strategy, evidence generation, and organizational decision-making.
  • Serve as a scientific peer-to-peer resource to disease experts and the broader medical community by providing timely, balanced, evidence-based scientific and clinical information.
  • Identify and cultivate relationships with potential investigators and provide field-based medical support for clinical trials, registries, real-world evidence initiatives, and other research programs.
  • Collaborate cross-functionally to provide scientific expertise and contribute to the development and execution of medical, scientific, and strategic initiatives at local, regional, and national levels.
  • Identify opportunities to advance patient care through research collaborations, educational initiatives, understanding care pathways and scientific or educational gaps, and other scientific partnership opportunities within key accounts and institutions.
  • Interpret and communicate complex scientific and clinical data to address the educational and research needs of healthcare professionals, investigators, and other stakeholders, aligned with Rhythm Medical Communications and medical strategy.
  • Maintain effective and appropriate communication among internal stakeholders, including Medical Affairs colleagues and Medical Information, while complying with relevant company, industry, legal, and regulatory requirements.
  • Respond to unsolicited requests for medical information in a timely, accurate, balanced, and compliant manner.
  • Contribute to North America Medical Affairs initiatives, congress activities, field medical training programs, and other strategic projects as needed.

Desired Qualifications

  • Experience in rare disease, obesity, endocrinology, neurology, genetics, pediatrics, or other specialty therapeutic areas.

About the Company

Rhythm Pharmaceuticals

Commercializes MC4R-targeted therapies for rare obesity

Rhythm Pharmaceuticals focuses on developing therapies for rare neuroendocrine genetic obesity disorders, led by IMCIVREE (setmelanotide). IMCIVREE is an MC4R agonist that restores signaling in the MC4R pathway to curb hunger and regulate energy use; it is FDA, EC, and MHRA approved for Bardet-Biedl syndrome and certain POMC/PCSK1/LEPR deficiencies in patients aged 2 and older, with revenue from global sales. The company differentiates itself by pursuing precision medicine for MC4R pathway diseases and advancing additional MC4R programs like bivamelagon and RM-718. Rhythm’s goal is to broaden access to MC4R-targeted therapies for rare patient populations and grow its pipeline toward sustainable commercialization.

Company size
501-1,000
Company stage
IPO
Headquarters
Boston, MA
Founded
2008

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