R

Roche

Global pharmaceuticals and diagnostics company

ERP Product Lifecycle Management Business Partner - Solution Architect BP

Full-TimeUpdated on 10/23/2026Deadline 11/6/26
$108.7k - $201.9k+ Discretionary annual bonus
Expert
Bachelor's, Master's
Indianapolis, IN, USA
In PersonMust work onsite in Indianapolis; relocation benefits are not available.
IT OperationsEnterprise Applications

About the job

Requirements
  • A Bachelor's or Master's degree in Information Technology, Computer Science, Engineering, Business Administration, or a related discipline is required.
  • At least 10 years of experience in ERP, PLM, or enterprise systems solution architecture, configuration, or technical business partnering roles is required.
  • Hands-on technical understanding and practical experience with PLM ecosystems, specifically PTC Windchill PLM and/or SAP PLM, alongside ERP platforms such as SAP S/4HANA, are required.
  • Strong understanding of SAP integration with MM (Materials Management), PP/PI (Production Planning and Execution), PM (Plant Maintenance), QM (Quality Management), and SD (Sales & Distribution) modules is required.
  • Strong understanding of Customer Services Area business processes and how they are captured in SAP objects, including Installed Base and Equipment Maintenance, is required.
  • Technical experience supporting manufacturing, supply chain, product development, engineering, change management, or quality processes is required.
  • Ability to work across global, matrixed organizations is required.
  • Strong analytical, solution architecture, communication, and stakeholder management skills are required.
  • Experience operating in regulated industries such as healthcare, medical devices, diagnostics, or pharmaceuticals is required.
  • Must be willing to work onsite in Indianapolis.
Responsibilities
  • Serve as the primary Informatics business partner for ERP and PLM initiatives within Roche Diagnostics and Roche Diabetes Care.
  • Build relationships with stakeholders across R&D, Manufacturing, Supply Chain, Quality, Regulatory, Commercial, and Operations teams.
  • Facilitate technical alignment between business strategy and enterprise technology roadmaps.
  • Drive communication between business users, solution architects, vendors, and delivery teams.
  • Lead and support technical ERP and PLM transformation initiatives across Diagnostics and Diabetes Care.
  • Identify opportunities for technical process optimization, data model harmonization, and digital innovation.
  • Translate business requirements into functional and technical system architecture and solution designs.
  • Support implementation, enhancement, technical integration, and lifecycle management of enterprise ERP and PLM platforms, specifically PTC Windchill and/or SAP PLM.
  • Participate in global PLM initiatives and projects, ensuring technical consistency and scalability of solutions across Roche divisions.
  • Provide technical support for system testing, validation, and compliance in accordance with regulated industry standards such as GxP.
  • Troubleshoot technical issues, provide Tier-3 end-user support, and contribute to continuous improvement efforts.
  • Collaborate with enterprise architecture and data governance teams to ensure scalable, integrated, and compliant solutions.
  • Partner with Roche Diagnostics business units to support product development, manufacturing, and quality processes.
  • Support Roche Diabetes Care initiatives involving connected devices, product traceability, regulatory compliance, and lifecycle management.
  • Ensure systems and processes support global healthcare and medical device regulations.
  • Ensure ERP and PLM solutions comply with Roche quality standards, cybersecurity policies, and regulatory requirements.
  • Support technical validation activities and documentation in regulated environments.
  • Participate in governance boards, release planning, and portfolio prioritization activities.
  • Support organizational change management activities related to ERP and PLM technology adoption.
  • Develop and deliver stakeholder engagement and training strategies.
  • Drive continuous improvement through metrics, feedback, and operational excellence practices.
Desired Qualifications
  • Experience within Diagnostics, Medical Devices, or Diabetes Care environments is preferred.
  • Hands-on knowledge of product lifecycle management processes, including design control, engineering change management, BOM management, and product master data governance, is preferred.
  • Familiarity with Agile delivery methodologies and product-centric operating models is preferred.
  • Experience with system integrations between ERP, PLM, MES, QMS, and related enterprise platforms using REST/SOAP APIs, middleware, or ETL tools is preferred.
  • Understanding of GxP, FDA 21 CFR Part 11/820, ISO 13485, and other healthcare regulatory frameworks is preferred.

About the company

Roche is a global leader in pharmaceuticals and diagnostics. It develops medicines and diagnostic tools that help detect, monitor, and treat diseases, using research and biotechnology to drive new therapies and tests. Roche combines drug development with in-house diagnostic products to support personalized medicine, where treatments are tailored to individual patients based on test results. Its approach differs from many peers by integrating drug discovery with diagnostic capabilities and by expanding its research through strategic acquisitions (like Genentech) to strengthen its biotechnology and R&D capabilities. The company’s goal is to improve patient outcomes and healthcare worldwide by delivering reliable medicines, accurate diagnostic tests, and data-driven care.

Company Size

1-10

Company Stage

IPO

Headquarters

Basel, Switzerland

Founded

1896

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Simplify's Take

What believers are saying

  • Enicepatide delivered 15.5% weight loss in September 2026 and 22.7% in June.
  • pTau217 can scale immediately through Roche's existing lab network and improve Alzheimer diagnostics.
  • Roche's June 2026 data and September 2026 filings signal multiple obesity shots on goal.

What critics are saying

  • Eli Lilly and Novo Nordisk dominate obesity pricing, distribution, and physician mindshare today.
  • Enicepatide remains Phase II-only; Roche starts late-stage glycemic and cardiovascular studies in 2027.
  • If enicepatide disappoints, Roche burns its $2.7 billion Carmot bet and loses obesity credibility.

What makes Roche unique

  • Roche combines pharma, diagnostics, and installed cobas labs across 4,500 U.S. instruments.
  • Elecsys pTau217 won FDA clearance on August 24, 2026, and CE marking September 7.
  • Roche controls obesity assets from Carmot and Zealand, spanning GLP-1/GIP and amylin.

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Benefits

  • Performance Bonus

Company News

Yahoo Finance
Oct 22nd, 2026
Roche reaffirms outlook as Q3 sales rise 7% to $19.6B, but growth doubts linger

Roche reaffirmed its 2025 outlook on Thursday and beat third-quarter sales expectations, but questions about its long-term growth remain. Group sales rose 7% to 16.1 billion Swiss francs (about $19.6 billion), ahead of the 15.8 billion franc consensus estimate. Jefferies analyst Michael Leuchten said a new resource planning system boosted revenue, making the results "cosmetically ahead." Roche still expects group sales growth in the "mid single digit range" and did not raise guidance. Sales of allergy and asthma drug Xolair reached only 848 million francs, well below estimates. A copycat version launched in the US this month, and Ocrevus and Tecentriq face generic competition by 2030. Roche is counting on its breast cancer pill giredestrant, which awaits a US Food and Drug Administration decision by December 18, and on obesity drugs. It says the products could together reach $9 billion in peak annual sales.

CNBC
Oct 22nd, 2026
Roche CEO presses Germany on growth strategy as drugmaker pauses investment there

Roche chief executive officer Thomas Schinecker has challenged Germany over its growth strategy, saying pharmaceutical firms are "the industry they need to bet on." Schinecker discussed the company's third-quarter earnings and its recent expansion in China. He also outlined recent pharmaceutical developments at the business. He explained why Roche has paused investment in Germany.

Yahoo Finance
Oct 16th, 2026
FDA approves Roche's Enspryng as first at-home injection for thyroid eye disease

Roche said the US Food and Drug Administration (FDA) has approved Enspryng (satralizumab) for adults with thyroid eye disease (TED). It is the first and only at-home subcutaneous treatment for the condition, and a patient or caregiver can administer it after training. In the Phase III SatraGO-2 trial, 52.9% of active TED patients on Enspryng had a proptosis (eye bulging) response, against 23.4% on placebo. Double vision fell in 60.7% of patients, against 25.8%. The SatraGO-1 trial missed its primary endpoint at Week 24. No new safety signals emerged. TED affects about 155 in every 100,000 people in the US. This is Enspryng's second approval, after neuromyelitis optica spectrum disorder in 2020. The FDA is also reviewing it for myelin oligodendrocyte glycoprotein antibody-associated disease, with a decision expected in January 2027.

Yahoo Finance
Oct 9th, 2026
FDA approves Roche's Tecentriq for stage III colon cancer, cutting recurrence risk by 50%

The US Food and Drug Administration has approved Roche's Tecentriq in combination with a fluoropyrimidine and oxaliplatin for adjuvant treatment of stage III deficient DNA mismatch repair colon cancer. This marks Tecentriq's twelfth approved indication in the US. The approval follows the phase III ATOMIC study, published in The New England Journal of Medicine, which demonstrated that Tecentriq plus chemotherapy reduced the risk of disease recurrence or death by 50% compared to chemotherapy alone. The 36-month disease-free survival rate was 86% with the combination versus 76% with chemotherapy alone. Nearly 25% of colon cancers are diagnosed at stage III, and almost one in three stage III patients experience recurrence within five years. This represents the first approved adjuvant immunotherapy regimen for this patient population. Roche is pursuing further regulatory filings, including with the European Medicines Agency.

Yahoo Finance
Sep 30th, 2026
Roche's enicepatide shows 22.5% weight loss in 48 weeks, challenging Eli Lilly and Novo Nordisk

Roche posted strong Phase 2 results for its weight loss drug enicepatide, showing 22.5% mean weight loss over 48 weeks. This compares favourably to Eli Lilly's Zepbound, which achieved 20.2% weight loss over 72 weeks in a separate trial. In another Phase 2 study, enicepatide demonstrated HbA1c reductions of up to 2.65 percentage points in diabetic patients after 48 weeks, compared to tirzepatide's 2.37 percentage points after 52 weeks. Despite promising results, Roche faces stiff competition from Novo Nordisk and Eli Lilly, which both have deep pipelines in development. Novo Nordisk's CagriSema is nearing approval, whilst Eli Lilly's retatrutide has posted strong Phase 3 results. Roche's revenue grew 6% year over year in the first half of the year to 30.4 billion Swiss francs.