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Prime Medicine

Develops Prime Editing gene therapies

Laboratory Operations Specialist

Manufacturing Quality & TestConfirmed live in the last 24 hours
Full-timeCambridge, MA, USA$92k - $103kIn-person

About the Job

Requirements

  • Associate's or bachelor's degree in a life science or technical field, or equivalent hands-on laboratory experience.
  • Experience maintaining equipment in a GMP-regulated laboratory.
  • Working knowledge of calibration and asset management systems such as Qualer.
  • Strong organizational skills and comfort managing multiple vendors and schedules at once.

Responsibilities

  • Own the master service calendar for all laboratory instruments and equipment, scheduling every qualification, preventive maintenance, calibration, and repair visit with outside vendors.
  • Arrange repair service with vendors to return instruments to working order.
  • Carry out equipment maintenance and calibration directly or through a vendor technician.
  • Confirm that records satisfy SOP requirements and specifications, escalating any deviations or excursions to QA.
  • Serve as the business owner of Qualer as the system of record for equipment and calibration, maintaining equipment records, calibration certificates, maintenance logs, and service records ready for inspection.
  • Track the calibration and maintenance status of every instrument and tag equipment that falls out of service or calibration due date.
  • Periodically reconcile the physical equipment inventory against Qualer and review upcoming or overdue activities, recurring failures, and other equipment-performance trends.
  • Serve as the business owner of Elemental Machines as the monitoring system for controlled temperature storage units.
  • Monitor Elemental Machines for alerts and alarms, acknowledging, communicating, and investigating as required by procedure.
  • Maintain vendor service contacts, scopes of work, access requirements, and performance records.
  • Provide input into the qualification or periodic evaluation of critical calibration and maintenance vendors.

About the Company

Prime Medicine

Develops Prime Editing gene therapies

Prime Medicine develops gene-editing therapies designed to treat a wide range of genetic diseases. The company utilizes a specific technology called "Prime Editing," which acts like a DNA word processor. This system can search for a specific location in the genetic code and replace a faulty segment of DNA with a corrected version, restoring normal function to the gene. Unlike earlier gene-editing methods like CRISPR-Cas9, which often create double-stranded breaks in DNA that can lead to unpredictable insertions or deletions, Prime Editing makes precise changes without breaking both strands of the DNA helix. This approach allows for more control over the final genetic sequence and reduces the risk of unintended mutations. The company’s goal is to create one-time curative treatments that can halt or prevent genetic disorders, providing lifelong health benefits to patients by addressing the root cause of their conditions at the molecular level.

Company size
51-200
Company stage
IPO
Headquarters
Cambridge, MA
Founded
2019

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